Marie Mooney, PhD

Assistant Professor, University of North Florida specializing in Genetics, Neuroscience, and Bioinformatics

Research Expertise

translational medicine

bioinformatics

neuro-oncology

oncology

neurodevelopmental disorders

Behavioral Neuroscience

Experimental and Cognitive Psychology

Physiology (medical)

Physiology

Genetics (clinical)

Genetics

Cell Biology

Molecular Biology

Biochemistry

Pharmacology

Molecular Medicine

Cancer Research

Plant Science

About

Marie Mooney, PhD is an Assistant Professor of Bioinformatics at the University of North Florida. She holds a PhD in Cell and Molecular Genetics from the Van Andel Research Institute, a MS in Biomedical Engineering from the University of Cincinnati, and a BS in Bioinformatics, from Michigan Technological University. Prior to her current role, she served as a Senior Postdoctoral Associate at Lurie Children's Hospital, A T32 Postdoctoral Scholar In Applied Genomics and Precision Medicine at Duke University, a Research Associate at Michigan State University. Her research focuses on integrative and translational approaches to repurpose therapeutics for use in rare congenital disorders. Her laboratory uses zebrafish as a genetic model organism to generate and test bioinformatics-driven hypotheses.

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Publications

Acute exposure to a high-fat diet alters meal patterns and body composition

Physiology & Behavior

2010

Comparative RNA-Seq and Microarray Analysis of Gene Expression Changes in B-Cell Lymphomas of Canis familiaris

PLoS ONE

2013

Meal patterns and hypothalamic NPY expression during chronic social stress and recovery

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

2010

Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations

American Journal of Medical Genetics Part A

2015

Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma

Biochemical Journal

2018

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

Nature Communications

2020

Anti-tumor effect of sulfasalazine in neuroblastoma

Biochemical Pharmacology

2019

Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia

Genetics in Medicine

2019

A multi-site feasibility study for personalized medicine in canines with Osteosarcoma

Journal of Translational Medicine

2013

Analysis of Single Nucleotide Variants in CRISPR-Cas9 Edited Zebrafish Exomes Shows No Evidence of Off-Target Inflation

Frontiers in Genetics

2019

Analysis of single nucleotide variants in CRISPR-Cas9 edited zebrafish embryos shows no evidence of off-target inflation

Unknown Venue

2019

Abstract 4027: Regulation of p16INK4A and TGF-beta by DNA hydroxymethylation in glioblastoma multiforme

Cancer Research

2012

Elucidating Metastatic Behavior Through Nanopatterned Membranes

Unknown Venue

2010

The CIMS (Cyanobacterial ITS motif slicer) for molecular systematics

Fottea

2023

Education

Duke University

Postdoctoral Associate/Scholar, School of medicine / June, 2020

Durham , North Carolina, United States of America

Michigan State University

Postdoctoral Fellow, Pediatrics and Human Development / October, 2017

Grand Rapids, Michigan, United States of America

Van Andel Research Institute

Cell and Molecular Genetics, PhD, Graduate School / March, 2016

Grand Rapids, Michigan, United States of America

University of Cincinnati

Biomedical Engineering, MS, Biomedical Engineering / July, 2010

Cincinnati, Ohio, United States of America

Michigan Technological University

Bioinformatics, BS, suma cum laude, Biology / December, 2006

Houghton, Michigan, United States of America

Experience

University of North Florida

Assisstant Professor of Bioinformatics / August, 2021 — Present

Lurie Children's Hospital

Postdoctoral Associate / July, 2020 — June, 2021

Duke University

Postdoctoral Associate / February, 2018 — June, 2020

Michigan State University

Postdoctoral Fellow/Research Associate / April, 2016 — October, 2017

Links & Social Media

Research Web Site

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