Frank Scannapieco

Dr. Scannapieco is an expert in oral microbiology and periodontology, and a pioneer in studies connecting oral and systemic diseases, including respiratory diseases such as pneumonia and COPD, diabetes and oral cancer.

Research Expertise

Oral Microbiology
Saliva
Periodontal Medicine
Periodontology

About

Dr. Scannapieco is a pioneer in studies connecting oral and systemic diseases, including respiratory diseases such as pneumonia and COPD, diabetes and oral cancer. Dr. Scannapieco has served on the UB faculty since 1991 and served as the Chair of the Department of Oral Biology from 2004 through 2022. Over the course of his career, he has edited several books and journal supplements and published more than 190 research articles and book chapters. He has received several awards, among these, promotion to SUNY Distinguished Professor, Distinguished Scientist Award in Oral Biology from the International Association for Dental Research, and Distinguished Scientist Awards in Oral Biology and Geriatric Oral Research from the International Association for Dental Research, the Irwin D. Mandel Distinguished Mentoring Award from the American Association for Dental Research, the Dean’s Award and Commencement Speaker from the University at Buffalo School of Dental Medicine, and the Doctor Honoris Causa from the Faculty of Dental Medicine, Carol Davila University of Medicine, Bucharest, Romania.

Publications

Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies
The Lancet Infectious Diseases
2013
Role of Oral Bacteria in Respiratory Infection
Journal of Periodontology
1999
Periodontal systemic associations: review of the evidence
Journal of Periodontology
2013
Associations Between Periodontal Disease and Risk for Atherosclerosis, Cardiovascular Disease, and Stroke. A Systematic Review
Annals of Periodontology
2003
Associations Between Periodontal Disease and Risk for Nosocomial Bacterial Pneumonia and Chronic Obstructive Pulmonary Disease. A Systematic Review
Annals of Periodontology
2003
Oral biofilms, periodontitis, and pulmonary infections
Oral Diseases
2007
Colonization of dental plaque by respiratory pathogens in medical intensive care patients
Critical Care Medicine
1992
Potential Associations Between Chronic Respiratory Disease and Periodontal Disease: Analysis of National Health and Nutrition Examination Survey III
Journal of Periodontology
2001
Saliva-Bacterium Interactions in Oral Microbial Ecology
Critical Reviews in Oral Biology & Medicine
1994
Relationships Between Periodontal Disease and Bacterial Pneumonia
Journal of Periodontology
1996
Associations Between Oral Conditions and Respiratory Disease in a National Sample Survey Population
Annals of Periodontology
1998
Salivary α-Amylase: Role in Dental Plaque and Caries Formation
Critical Reviews in Oral Biology & Medicine
1993
Periodontal Diseases' Contributions to Cardiovascular Disease: An Overview of Potential Mechanisms
Annals of Periodontology
1998
Chronic Periodontitis and the Incidence of Head and Neck Squamous Cell Carcinoma
Cancer Epidemiology, Biomarkers & Prevention
2009
Oral inflammation and infection, and chronic medical diseases: implications for the elderly
Periodontology 2000
2016
Periodontal Disease as a Risk Factor for Adverse Pregnancy Outcomes. A Systematic Review
Annals of Periodontology
2003
Respiratory pathogen colonization of the dental plaque of institutionalized elders
Special Care in Dentistry
1999
Pneumonia in nonambulatory patients
The Journal of the American Dental Association
2006
Oral hygiene and periodontal status in a group of institutionalized hearing impaired individuals in Pondicherry - A descriptive study
Journal of Indian Association of Public Health Dentistry
2002
Chronic Periodontitis and the Risk of Tongue Cancer
Archives of Otolaryngology–Head & Neck Surgery
2007
A randomized trial of chlorhexidine gluconate on oral bacterial pathogens in mechanically ventilated patients
Critical Care
2009
Genetic Relationships between Respiratory Pathogens Isolated from Dental Plaque and Bronchoalveolar Lavage Fluid from Patients in the Intensive Care Unit Undergoing Mechanical Ventilation
Clinical Infectious Diseases
2008
Periodontal Inflammation: From Gingivitis to Systemic Disease?
Gingival Diseases - Their Aetiology, Prevention and Treatment
2011
Nursing home‐associated pneumonia, hospital‐acquired pneumonia and ventilator‐associated pneumonia: the contribution of dental biofilms and periodontal inflammation
Periodontology 2000
2007
Association of periodontal infections with atherosclerotic and pulmonary diseases
Journal of Periodontal Research
1999
Periodontitis and respiratory diseases: A systematic review with meta‐analysis
Oral Diseases
2019
Global Metabolomic Analysis of Human Saliva and Plasma from Healthy and Diabetic Subjects, with and without Periodontal Disease
PLoS ONE
2014
Estimated prevalence of halitosis: a systematic review and meta-regression analysis
Clinical Oral Investigations
2017
The prevention of periodontal disease—An overview
Periodontology 2000
2020
The Epidemiology, Consequences and Management of Periodontal Disease in Older Adults
The Journal of the American Dental Association
2007
Oral‐lung microbiome interactions in lung diseases
Periodontology 2000
2020
Associations between dental caries and systemic diseases: a scoping review
BMC Oral Health
2021
Characterization of salivary alpha-amylase binding to Streptococcus sanguis
Infection and Immunity
1989
Salivary Amylase Promotes Adhesion of Oral Streptococci to Hydroxyapatite
Journal of Dental Research
1995
Dysbiosis revisited: Understanding the role of the oral microbiome in the pathogenesis of gingivitis and periodontitis: A critical assessment
Journal of Periodontology
2021
Oral Bacteria and Respiratory Infection: Effects on Respiratory Pathogen Adhesion and Epithelial Cell Proinflammatory Cytokine Production
Annals of Periodontology
2001
Systemic Effects of Periodontal Diseases
Dental Clinics of North America
2005
The oral microbiome: Its role in health and in oral and systemic infections
Clinical Microbiology Newsletter
2013
Human submandibular-sublingual saliva promotes adhesion of Candida albicans to polymethylmethacrylate
Infection and Immunity
1993
“Does Periodontal Therapy Reduce the Risk for Systemic Diseases?”
Dental Clinics of North America
2010
Role of Streptococcus gordonii Amylase-Binding Protein A in Adhesion to Hydroxyapatite, Starch Metabolism, and Biofilm Formation
Infection and Immunity
2001
Formation of salivary-mucosal pellicle: the role of transglutaminase
Biochemical Journal
1992
Candidate salivary biomarkers associated with alveolar bone loss: cross-sectional andin vitrostudies
FEMS Immunology & Medical Microbiology
2007
Oral Health Disparities in Older Adults
Dental Clinics of North America
2014
Inhibition of Proinflammatory Activities of Major Periodontal Pathogens by Aqueous Extracts From Elder Flower (Sambucus nigra)
Journal of Periodontology
2006
Role of periodontal therapy in management of common complex systemic diseases and conditions: An update
Periodontology 2000
2018
Identification and Molecular Analysis of Rough-Colony-Specific Outer Membrane Proteins of Actinobacillus actinomycetemcomitans
Infection and Immunity
1999
Oral Mucosa Harvest: An Overview of Anatomic and Biologic Considerations
EAU-EBU Update Series
2007
Microbial adhesion to ionogenic PHEMA, PU and PP implants
Biomaterials
1996
Emergence in Human Dental Plaque and Host Distribution of Amylase-binding Streptococci
Journal of Dental Research
1994
Is there association between stress and periodontitis?
Clinical Oral Investigations
2019
Epidemiological Evidence for the Relationship Between Upper and Lower Airway Diseases
Upper and Lower Respiratory Disease
2003
Molecular analysis of bacterial flora associated with chronically inflamed maxillary sinuses
Journal of Medical Microbiology
2003
The Use of Different Measurements and Definitions of Periodontal Disease in the Study of the Association Between Periodontal Disease and Risk of Myocardial Infarction
Journal of Periodontology
2006
The salivary microbiome of diabetic and non‐diabetic adults with periodontal disease
Journal of Periodontology
2018
Salivary inflammatory markers and microbiome in normoglycemic lean and obese children compared to obese children with type 2 diabetes
PLOS ONE
2017
The Role of Pili and Capsule in the Pathogenesis of Neonatal Infection with Escherichia coli Kl
Journal of Infectious Diseases
1983
Exploring the salivary microbiome of children stratified by the oral hygiene index
PLOS ONE
2017
Local Inflammation and Human Papillomavirus Status of Head and Neck Cancers
Archives of Otolaryngology–Head & Neck Surgery
2012
Performance of Multiplex Cytokine Assays in Serum and Saliva among Community-Dwelling Postmenopausal Women
PLoS ONE
2013
Poor Oral Health in the Etiology and Prevention of Aspiration Pneumonia
Dental Clinics of North America
2021
Taking the Starch out of Oral Biofilm Formation: Molecular Basis and Functional Significance of Salivary α-Amylase Binding to Oral Streptococci
Applied and Environmental Microbiology
2013
Structural relationship between the enzymatic and streptococcal binding sites of human salivary α-amylase
Biochemical and Biophysical Research Communications
1990
Effect of anaerobiosis on the surface ultrastructure and surface proteins of Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans)
Infection and Immunity
1987
Oral bacteria modulate invasion and induction of apoptosis in HEp-2 cells by Pseudomonas aeruginosa
Microbial Pathogenesis
2009
Lubrication of selected salivary molecules and artificial salivas
Dysphagia
1989
Salivary Biomarkers Associated with Alveolar Bone Loss
Annals of the New York Academy of Sciences
2007
Association between osteoporosis treatment and severe periodontitis in postmenopausal women
Menopause
2017
Severity of Periodontitis and Metabolic Syndrome: Is There an Association?
Journal of Periodontology
2016
Formal debate: an active learning strategy
Journal of Dental Education
1997
History of periodontal disease diagnosis and lung cancer incidence in the Women’s Health Initiative Observational Study
Cancer Causes & Control
2014
Dental Caries and Head and Neck Cancers
JAMA Otolaryngology–Head & Neck Surgery
2013
Supragingival Plaque May Modify the Effects of Subgingival Bacteria on Attachment Loss
Journal of Periodontology
2006
Medical considerations relating to the oral health of older adults
Special Care in Dentistry
2013
Host Defense Proteins Derived from Human Saliva Bind to Staphylococcus aureus
Infection and Immunity
2013
Identification and analysis of a gene (abpA) encoding a major amylase-binding protein in Streptococcus gordonii
Microbiology
1998
What is the future of Periodontal Medicine?
Brazilian Oral Research
2021
Porphyromonas gingivalis modulates Pseudomonas aeruginosa-induced apoptosis of respiratory epithelial cells through the STAT3 signaling pathway
Microbes and Infection
2014
Nosocomial Pneumonia and Oral Health
Special Care in Dentistry
2005
Interaction of Salivary alpha-Amylase and Amylase-Binding-Protein A (AbpA) of Streptococcus gordonii with Glucosyltransferase of S. gordonii and Streptococcus mutans
BMC Microbiology
2007
Environmental influences on Actinobacillus actinomycetemcomitans biofilm formation
Archives of Oral Biology
2006
Streptococcus mutans Out-competes Streptococcus gordonii in vivo
Journal of Dental Research
2012
Genetic relationships between Candida albicans strains isolated from dental plaque, trachea, and bronchoalveolar lavage fluid from mechanically ventilated intensive care unit patients
Journal of Oral Microbiology
2011
Periodontitis and Chronic Kidney Disease
Journal of Periodontology
2008
Role of Type 1 Fimbriae in the Adhesion of Escherichia coli to Salivary Mucin and Secretory Immunoglobulin A
Current Microbiology
1996
Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss
Cell Death & Differentiation
2015
Is Radiologic Assessment of Alveolar Crest Height Useful to Monitor Periodontal Disease Activity?
Dental Clinics of North America
2015
Amylase-binding proteins A (AbpA) and B (AbpB) differentially affect colonization of rats' teeth by Streptococcus gordonii
Microbiology
2003
Severe and moderate periodontitis are associated with acute myocardial infarction
Journal of Periodontology
2020
MyPro: A seamless pipeline for automated prokaryotic genome assembly and annotation
Journal of Microbiological Methods
2015
Transcriptional and Translational Analysis of Biofilm Determinants of Aggregatibacter actinomycetemcomitans in Response to Environmental Perturbation
Infection and Immunity
2009
Observation of fimbriae and flagella in dispersed subgingival dental plaque and fresh bacterial isolates from periodontal disease
Journal of Periodontal Research
1983
Modest Reduction in Risk for Ventilator-Associated Pneumonia in Critically ill Patients Receiving Mechanical Ventilation Following Topical Oral Chlorhexidine
Journal of Evidence Based Dental Practice
2012
The Microbial Ecology and Immunology of the Adenoid: Implications for Otitis Media
Annals of the New York Academy of Sciences
1997
Characterization of an amylase-binding component of Streptococcus gordonii G9B
Infection and Immunity
1992
Association between periodontitis and severe asthma in adults: A case–control study
Oral Diseases
2017
Prevalence of the Amylase-Binding Protein A Gene ( abpA ) in Oral Streptococci
Journal of Clinical Microbiology
1999
Saliva and dental health. Clinical implications of saliva: report of a consensus meeting
British Dental Journal
1990
Epidemiological associations between periodontitis and cancer
Periodontology 2000
2024

Education

D.M.D., Dentistry / May, 1985

Farmington, CT, New York, United States of America

Oral Biology / February, 1991

Buffalo, NY, New York, United States of America

Experience

University at Buffalo

Links & Social Media

Join Frank on NotedSource!
Join Now

At NotedSource, we believe that professors, post-docs, scientists and other researchers have deep, untapped knowledge and expertise that can be leveraged to drive innovation within companies. NotedSource is committed to bridging the gap between academia and industry by providing a platform for collaboration with industry and networking with other researchers.

For industry, NotedSource identifies the right academic experts in 24 hours to help organizations build and grow. With a platform of thousands of knowledgeable PhDs, scientists, and industry experts, NotedSource makes connecting and collaborating easy.

For academic researchers such as professors, post-docs, and Ph.D.s, NotedSource provides tools to discover and connect to your colleagues with messaging and news feeds, in addition to the opportunity to be paid for your collaboration with vetted partners.

Expert Institutions
NotedSource has experts from Stanford University
Expert institutions using NotedSource include Oxfort University
Experts from McGill have used NotedSource to share their expertise
University of Chicago experts have used NotedSource
MIT researchers have used NotedSource
Proudly trusted by
Microsoft uses NotedSource for academic partnerships
Johnson & Johnson academic research projects on NotedSource
ProQuest (Clarivate) uses NotedSource as their industry academia platform
Slamom consulting engages academics for research collaboration on NotedSource
Omnicom and OMG find academics on notedsource
Unilever research project have used NotedSource to engage academic experts

Connect with researchers and scientists like Frank Scannapieco on NotedSource to help your company with innovation, research, R&D, L&D, and more.