Sandeep Kakade

Materials Scientist with background in Nanotechnology and Microparticle based Drug Delivery Systems

Research Expertise

Cardiovascular Drug Eluting Stents

Drug Delivery

Microparticles for Immune Modulation

DNA Vaccines

Bioengineering

Biophysics

Biomaterials

Mechanics of Materials

Pharmaceutical Science

Spectroscopy

Electrochemistry

Surfaces and Interfaces

Condensed Matter Physics

Pharmacology

Drug Discovery

Immunology and Allergy

Immunology

Oncology

Cancer Research

Molecular Biology

Biotechnology

Biochemistry

Biomedical Engineering

About

Seasoned Materials Scientist with expertise in Polymer Science, Colloids & Interfacial Science, nanoparticle, and microparticle-based drug delivery systems. Studied and worked in nanomedicine for the past 20 years with more than 14 years of experience carrying out research in drug/gene/protein delivery systems for atherosclerosis, autoimmune diseases, allergy, and inflammation. Dynamic and results driven R&D professional with a proven track record of delivering scientific innovation, quality, and efficiency. Adept with GLP/GMP based documentation and processes. Apply chemical engineering principles to the Pharmaceutical and Biotechnology Industry. <br> Published in peer-reviewed journals including Biomaterials, Journal of Immunology, Langmuir, Nanoscale, Frontiers in Oncology, and International Journal of Pharmaceutics.

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Publications

Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation

Biomaterials

2019

Transfection activity of layer-by-layer plasmid DNA/poly(ethylenimine) films deposited on PLGA microparticles

International Journal of Pharmaceutics

2009

Microrough Cobalt–Chromium Alloy Surfaces for Paclitaxel Delivery: Preparation, Characterization, and In Vitro Drug Release Studies

Langmuir

2012

A comparative study of the effects of vitamin C, sirolimus, and paclitaxel on the growth of endothelial and smooth muscle cells for cardiovascular medical device applications

Drug Design, Development and Therapy

2013

Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic β Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice

The Journal of Immunology

2022

Rapid and sensitive detection of cardiac troponin I using a force enhanced immunoassay with nanoporous membrane

Nanoscale

2020

Myeloid cell reprogramming alleviates immunosuppression and promotes clearance of metastatic lesions

Frontiers in Oncology

2022

Tolerogenic Immune Modifying Nanoparticles (TIMP) Encapsulating Multiple Diabetogenic Epitopes Prevent Onset of Type 1 Diabetes in NOD Mice

The Journal of Immunology

2022

Vitamin-C Delivery from CoCr Alloy Surfaces Using Polymer-Free and Polymer-Based Platforms For Cardiovascular Stent Applications

Langmuir

2014

Education

Iowa State University

Master of Engineering, Chemical and Biological Engineering / May, 2011

Ames, Iowa, United States of America

Wayne State University

Master of Science in Materials Science & Engineering, Chemical Engineering & Materials Science / May, 2007

Detroit, Michigan, United States of America

BMS College of Engineering

Bachelor of Engineering in Chemical , Chemical Engineering / September, 2001

Bangalore

Experience

The University of Michigan and Cour Pharmaceuticals

Senior Scientist: Drug Product Discovery / July, 2018 — Present

The University of South Dakota

Lab Manager / October, 2011 — May, 2015

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