Sandeep Kakade

Materials Scientist with background in Nanotechnology and Microparticle based Drug Delivery Systems

Greater Chicago Area, Illinois, United States of America

Research Expertise

Cardiovascular Drug Eluting Stents

Drug Delivery

Microparticles for Immune Modulation

DNA Vaccines

Bioengineering

Biophysics

Biomaterials

Mechanics of Materials

Pharmaceutical Science

Spectroscopy

Electrochemistry

Surfaces and Interfaces

Condensed Matter Physics

Pharmacology

Drug Discovery

Immunology and Allergy

Immunology

Oncology

Cancer Research

Molecular Biology

Biotechnology

Biochemistry

Biomedical Engineering

About

Materials Scientist and CMC Lead with over 18 years of experience in R&D and technical development of sterile injectables and parenteral nanomedicine formulations. Expertise spans polymer physics, colloids, and nanoparticle/microparticle engineering, with more than 14 years dedicated to advancing drug, gene, and protein delivery platforms. Demonstrated success in translating scientific innovation into clinical trials, contributing to therapeutic advances in atherosclerosis, cancer immunotherapy, antigen-specific immune therapies, and T-cell–based treatments for autoimmune and inflammatory diseases. Recognized for strategic leadership across formulation, process development, and regulatory CMC, with proven proficiency in GLP/GMP documentation, IND/DMF authoring, and digital transformation initiatives. Skilled at integrating chemical engineering principles with drug delivery innovation to optimize processes, enhance quality, and accelerate clinical translation.

Legacy Map

Full View

Publications

Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation

Biomaterials

2019

Transfection activity of layer-by-layer plasmid DNA/poly(ethylenimine) films deposited on PLGA microparticles

International Journal of Pharmaceutics

2009

Microrough Cobalt–Chromium Alloy Surfaces for Paclitaxel Delivery: Preparation, Characterization, and In Vitro Drug Release Studies

Langmuir

2012

A comparative study of the effects of vitamin C, sirolimus, and paclitaxel on the growth of endothelial and smooth muscle cells for cardiovascular medical device applications

Drug Design, Development and Therapy

2013

Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic β Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice

The Journal of Immunology

2022

Rapid and sensitive detection of cardiac troponin I using a force enhanced immunoassay with nanoporous membrane

Nanoscale

2020

Myeloid cell reprogramming alleviates immunosuppression and promotes clearance of metastatic lesions

Frontiers in Oncology

2022

Tolerogenic Immune Modifying Nanoparticles (TIMP) Encapsulating Multiple Diabetogenic Epitopes Prevent Onset of Type 1 Diabetes in NOD Mice

The Journal of Immunology

2022

Vitamin-C Delivery from CoCr Alloy Surfaces Using Polymer-Free and Polymer-Based Platforms For Cardiovascular Stent Applications

Langmuir

2014

Education

Iowa State University

Master of Science, Chemical Engineering / May, 2011

Ames, Iowa, United States of America

Wayne State University

Master of Science, Materials Science & Engineering / May, 2007

Detroit, Michigan, United States of America

BMS College of Engineering

Bachelor of Engineering in Chemical , Chemical Engineering / September, 2001

Bangalore

Experience

Nanocan Therapeutics Corporation

Associate Director: CMC Formulation Development / September, 2024 — Present

The University of Michigan & COUR Pharma

Senior Scientist: Drug Product Discovery & Innovation / March, 2016 — September, 2024

The University of South Dakota & GEAR center for Applied Research

Lab Manager/Research Associate: IV, Drug Delivery Innovation / September, 2024 — Present

Join Sandeep on NotedSource!

Join Now

At NotedSource, we believe that professors, post-docs, scientists and other researchers have deep, untapped knowledge and expertise that can be leveraged to drive innovation within companies. NotedSource is committed to bridging the gap between academia and industry by providing a platform for collaboration with industry and networking with other researchers.

For industry, NotedSource identifies the right academic experts in 24 hours to help organizations build and grow. With a platform of thousands of knowledgeable PhDs, scientists, and industry experts, NotedSource makes connecting and collaborating easy.

For academic researchers such as professors, post-docs, and Ph.D.s, NotedSource provides tools to discover and connect to your colleagues with messaging and news feeds, in addition to the opportunity to be paid for your collaboration with vetted partners.