The growing demand for quality mental health care isn’t going anywhere. At OPTT, I lead a team of exceptional people to build digital mental health solutions for the population. Our team is working hard to change the way mental health care is delivered. With the use of AI technology, OPTT provides health care professionals with insights for effective care pathways.
Mohsen Omrani
CEO at OPTT Inc.
Research Expertise
About
Publications
Primary motor cortex underlies multi-joint integration for fast feedback control
Nature / Sep 28, 2011
Pruszynski, J. A., Kurtzer, I., Nashed, J. Y., Omrani, M., Brouwer, B., & Scott, S. H. (2011). Primary motor cortex underlies multi-joint integration for fast feedback control. Nature, 478(7369), 387–390. https://doi.org/10.1038/nature10436
Distributed task-specific processing of somatosensory feedback for voluntary motor control
eLife / Apr 14, 2016
Omrani, M., Murnaghan, C. D., Pruszynski, J. A., & Scott, S. H. (2016). Distributed task-specific processing of somatosensory feedback for voluntary motor control. ELife, 5. CLOCKSS. https://doi.org/10.7554/elife.13141
Perspectives on classical controversies about the motor cortex
Journal of Neurophysiology / Sep 01, 2017
Omrani, M., Kaufman, M. T., Hatsopoulos, N. G., & Cheney, P. D. (2017). Perspectives on classical controversies about the motor cortex. Journal of Neurophysiology, 118(3), 1828–1848. https://doi.org/10.1152/jn.00795.2016
Goal-Dependent Modulation of Fast Feedback Responses in Primary Motor Cortex
The Journal of Neuroscience / Mar 26, 2014
Pruszynski, J. A., Omrani, M., & Scott, S. H. (2014). Goal-Dependent Modulation of Fast Feedback Responses in Primary Motor Cortex. The Journal of Neuroscience, 34(13), 4608–4617. https://doi.org/10.1523/jneurosci.4520-13.2014
Rapid feedback corrections during a bimanual postural task
Journal of Neurophysiology / Jan 01, 2013
Omrani, M., Diedrichsen, J., & Scott, S. H. (2013). Rapid feedback corrections during a bimanual postural task. Journal of Neurophysiology, 109(1), 147–161. https://doi.org/10.1152/jn.00669.2011
Perturbation-evoked responses in primary motor cortex are modulated by behavioral context
Journal of Neurophysiology / Dec 01, 2014
Omrani, M., Pruszynski, J. A., Murnaghan, C. D., & Scott, S. H. (2014). Perturbation-evoked responses in primary motor cortex are modulated by behavioral context. Journal of Neurophysiology, 112(11), 2985–3000. https://doi.org/10.1152/jn.00270.2014
Online Cognitive Behavioral Therapy
Jan 01, 2019
Alavi, N., & Omrani, M. (2019). Online Cognitive Behavioral Therapy. https://doi.org/10.1007/978-3-319-99151-1
Rotational dynamics in motor cortex are consistent with a feedback controller
eLife / Nov 03, 2021
Kalidindi, H. T., Cross, K. P., Lillicrap, T. P., Omrani, M., Falotico, E., Sabes, P. N., & Scott, S. H. (2021). Rotational dynamics in motor cortex are consistent with a feedback controller. ELife, 10. CLOCKSS. https://doi.org/10.7554/elife.67256
Using the Online Psychotherapy Tool to Address Mental Health Problems in the Context of the COVID-19 Pandemic: Protocol for an Electronically Delivered Cognitive Behavioral Therapy Program
JMIR Research Protocols / Dec 18, 2020
Alavi, N., Yang, M., Stephenson, C., Nikjoo, N., Malakouti, N., Layzell, G., Jagayat, J., Shirazi, A., Groll, D., Omrani, M., O’Riordan, A., Khalid-Khan, S., Freire, R., Brietzke, E., Gomes, F. A., Milev, R., & Soares, C. N. (2020). Using the Online Psychotherapy Tool to Address Mental Health Problems in the Context of the COVID-19 Pandemic: Protocol for an Electronically Delivered Cognitive Behavioral Therapy Program. JMIR Research Protocols, 9(12), e24913. https://doi.org/10.2196/24913
Primary motor cortex neurons classified in a postural task predict muscle activation patterns in a reaching task
Journal of Neurophysiology / Apr 01, 2016
Heming, E. A., Lillicrap, T. P., Omrani, M., Herter, T. M., Pruszynski, J. A., & Scott, S. H. (2016). Primary motor cortex neurons classified in a postural task predict muscle activation patterns in a reaching task. Journal of Neurophysiology, 115(4), 2021–2032. https://doi.org/10.1152/jn.00971.2015
Effect of tactile stimulus frequency on time perception: the role of working memory
Experimental Brain Research / Nov 08, 2007
Khoshnoodi, M. A., Motiei-Langroudi, R., Omrani, M., Diamond, M. E., & Abbassian, A. H. (2007). Effect of tactile stimulus frequency on time perception: the role of working memory. Experimental Brain Research, 185(4), 623–633. https://doi.org/10.1007/s00221-007-1190-y
Kinesthetic memory in distance reproduction task: importance of initial hand position information
Experimental Brain Research / Nov 30, 2005
Khoshnoodi, M. A., Motiei-langroudi, R., Omrani, M., Ghaderi-pakdell, F., & Abbassian, A. H. (2005). Kinesthetic memory in distance reproduction task: importance of initial hand position information. Experimental Brain Research, 170(3), 312–319. https://doi.org/10.1007/s00221-005-0217-5
Delivering an online cognitive behavioural therapy program to address mental health challenges faced by correctional workers and other public safety personnel: Protocol (Preprint)
May 31, 2021
Alavi, N., Stephenson, C., Omrani, M., Gerritsen, C., Martin, M. S., Knyahnytskyi, A., Zhu, Y., Kumar, A., Jagayat, J., Shirazi, A., Moghimi, E., Patel, C., Knyahnytska, Y., Simpson, A. I., Zaheer, J., Andersen, J., Munshi, A., & Groll, D. (2021). Delivering an online cognitive behavioural therapy program to address mental health challenges faced by correctional workers and other public safety personnel: Protocol (Preprint). https://doi.org/10.2196/preprints.30845
Benefits of Digital Mental Health Care Interventions for Correctional Workers and Other Public Safety Personnel: A Narrative Review
Frontiers in Psychiatry / Jul 08, 2022
Moghimi, E., Knyahnytska, Y., Omrani, M., Nikjoo, N., Stephenson, C., Layzell, G., Frederic Simpson, A. I., & Alavi, N. (2022). Benefits of Digital Mental Health Care Interventions for Correctional Workers and Other Public Safety Personnel: A Narrative Review. Frontiers in Psychiatry, 13. https://doi.org/10.3389/fpsyt.2022.921527
Feasibility and Efficacy of Delivering Cognitive Behavioral Therapy Through an Online Psychotherapy Tool for Depression: Protocol for a Randomized Controlled Trial
JMIR Research Protocols / Jun 16, 2021
Alavi, N., Stephenson, C., Yang, M., Kumar, A., Shao, Y., Miller, S., Yee, C. S., Stefatos, A., Gholamzadehmir, M., Abbaspour, Z., Jagayat, J., Shirazi, A., Omrani, M., Patel, A., Patel, C., & Groll, D. (2021). Feasibility and Efficacy of Delivering Cognitive Behavioral Therapy Through an Online Psychotherapy Tool for Depression: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 10(6), e27489. https://doi.org/10.2196/27489
What Is Depression? What Is Anxiety?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Is Depression? What Is Anxiety? Online Cognitive Behavioral Therapy, 17–31. https://doi.org/10.1007/978-3-319-99151-1_3
Developing and Implementing a Web-Based Relapse Prevention Psychotherapy Program for Patients With Alcohol Use Disorder: Protocol for a Randomized Controlled Trial
JMIR Research Protocols / Jan 25, 2023
Eadie, J., Gutierrez, G., Moghimi, E., Stephenson, C., Khalafi, P., Nikjoo, N., Jagayat, J., Gizzarelli, T., Reshetukha, T., Omrani, M., Yang, M., & Alavi, N. (2023). Developing and Implementing a Web-Based Relapse Prevention Psychotherapy Program for Patients With Alcohol Use Disorder: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 12, e44694. https://doi.org/10.2196/44694
A qualitative exploration of the mental health challenges and therapeutic needs of Canadian correctional workers
Frontiers in Psychiatry / Oct 25, 2022
Moghimi, E., Knyahnytska, Y., Zhu, Y., Kumar, A., Knyahnytski, A., Patel, C., Omrani, M., Gerritsen, C., Martin, M., Simpson, A. I. F., & Alavi, N. (2022). A qualitative exploration of the mental health challenges and therapeutic needs of Canadian correctional workers. Frontiers in Psychiatry, 13. https://doi.org/10.3389/fpsyt.2022.1004143
Online Clinic, a New Method of Delivering Psychotherapy
European Psychiatry / Apr 01, 2017
Omrani, M., Alavi, N., Rivera, M., & Khalid-Khan, S. (2017). Online Clinic, a New Method of Delivering Psychotherapy. European Psychiatry, 41(S1), S148–S148. https://doi.org/10.1016/j.eurpsy.2017.01.1997
Learning not to feel: reshaping the resolution of tactile perception
Frontiers in Systems Neuroscience / Jan 01, 2013
Omrani, M., Lak, A., & Diamond, M. E. (2013). Learning not to feel: reshaping the resolution of tactile perception. Frontiers in Systems Neuroscience, 7. https://doi.org/10.3389/fnsys.2013.00029
Mental health challenges, treatment experiences, and care needs of post-secondary students: a cross-sectional mixed-methods study
BMC Public Health / Apr 06, 2023
Moghimi, E., Stephenson, C., Gutierrez, G., Jagayat, J., Layzell, G., Patel, C., McCart, A., Gibney, C., Langstaff, C., Ayonrinde, O., Khalid-Khan, S., Milev, R., Snelgrove-Clarke, E., Soares, C., Omrani, M., & Alavi, N. (2023). Mental health challenges, treatment experiences, and care needs of post-secondary students: a cross-sectional mixed-methods study. BMC Public Health, 23(1). https://doi.org/10.1186/s12889-023-15452-x
Developing and Implementing a Web-Based Psychotherapy Program to Address Mental Health Challenges Among Patients Receiving Oncologic and Palliative Care: Protocol for an Open-Label Randomized Controlled Trial
JMIR Research Protocols / Jul 14, 2021
Alavi, N., Stephenson, C., Miller, S., Khalafi, P., Sinan, I., Kain, D., McDougall, M., Davies, J., Stark, D., Tompkins, E., Jagayat, J., Omrani, M., Shirazi, A., Groll, D., & Soares, C. (2021). Developing and Implementing a Web-Based Psychotherapy Program to Address Mental Health Challenges Among Patients Receiving Oncologic and Palliative Care: Protocol for an Open-Label Randomized Controlled Trial. JMIR Research Protocols, 10(7), e30735. https://doi.org/10.2196/30735
Understanding and Rating Our Feelings, and the Thought Record
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). Understanding and Rating Our Feelings, and the Thought Record. Online Cognitive Behavioral Therapy, 69–79. https://doi.org/10.1007/978-3-319-99151-1_7
What Is the Five-Part Model and How Can It Be Helpful?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Is the Five-Part Model and How Can It Be Helpful? Online Cognitive Behavioral Therapy, 33–44. https://doi.org/10.1007/978-3-319-99151-1_4
Evaluating the Efficacy of Web-Based Cognitive Behavioral Therapy for the Treatment of Patients With Bipolar II Disorder and Residual Depressive Symptoms: Protocol for a Randomized Controlled Trial
JMIR Research Protocols / May 19, 2023
Gutierrez, G., Stephenson, C., Eadie, J., Moghimi, E., Omrani, M., Groll, D., Soares, C. N., Milev, R., Vazquez, G., Yang, M., & Alavi, N. (2023). Evaluating the Efficacy of Web-Based Cognitive Behavioral Therapy for the Treatment of Patients With Bipolar II Disorder and Residual Depressive Symptoms: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 12, e46157. https://doi.org/10.2196/46157
Investigating the effectiveness of electronically delivered cognitive behavioural therapy (e-CBTi) compared to pharmaceutical interventions in treating insomnia: Protocol for a randomized controlled trial
PLOS ONE / May 16, 2023
Zhu, Y., Stephenson, C., Moghimi, E., Jagayat, J., Nikjoo, N., Kumar, A., Shirazi, A., Patel, C., Omrani, M., & Alavi, N. (2023). Investigating the effectiveness of electronically delivered cognitive behavioural therapy (e-CBTi) compared to pharmaceutical interventions in treating insomnia: Protocol for a randomized controlled trial. PLOS ONE, 18(5), e0285757. https://doi.org/10.1371/journal.pone.0285757
Comparison of online and in-person cognitive behavioral therapy in individuals diagnosed with major depressive disorder: a non-randomized controlled trial
Frontiers in Psychiatry / Apr 28, 2023
Alavi, N., Moghimi, E., Stephenson, C., Gutierrez, G., Jagayat, J., Kumar, A., Shao, Y., Miller, S., Yee, C. S., Stefatos, A., Gholamzadehmir, M., Abbaspour, Z., Shirazi, A., Gizzarelli, T., Khan, F., Patel, C., Patel, A., Yang, M., & Omrani, M. (2023). Comparison of online and in-person cognitive behavioral therapy in individuals diagnosed with major depressive disorder: a non-randomized controlled trial. Frontiers in Psychiatry, 14. https://doi.org/10.3389/fpsyt.2023.1113956
User experiences of an online therapist-guided psychotherapy platform, OPTT: A cross-sectional study
Internet Interventions / Apr 01, 2023
Stephenson, C., Moghimi, E., Gutierrez, G., Jagayat, J., Layzell, G., Patel, C., Omrani, M., & Alavi, N. (2023). User experiences of an online therapist-guided psychotherapy platform, OPTT: A cross-sectional study. Internet Interventions, 32, 100623. https://doi.org/10.1016/j.invent.2023.100623
Investigating the effectiveness of incorporating a stepped care approach into electronically delivered CBT for depression
European Psychiatry / Mar 01, 2023
Alavi, N., Omrani, M., Jagayat, J., Shirazi, A., Kumar, A., Pannu, A., & Shao, Y. (2023). Investigating the effectiveness of incorporating a stepped care approach into electronically delivered CBT for depression. European Psychiatry, 66(S1), S481–S482. https://doi.org/10.1192/j.eurpsy.2023.1030
Efficacy of an electronic cognitive behavioural therapy program delivered via the Online Psychotherapy Tool for mental health problems related to the COVID-19 Pandemic: Pilot Study (Preprint)
Jul 20, 2023
Moghimi, E., Stephenson, C., Agrawal, A., Nikjoo, N., Malakouti, N., Layzell, G., O’Riordan, A., Jagayat, J., Shirazi, A., Gutierrez, G., Khan, F., Patel, C., Yang, M., Omrani, M., & Alavi, N. (2023). Efficacy of an electronic cognitive behavioural therapy program delivered via the Online Psychotherapy Tool for mental health problems related to the COVID-19 Pandemic: Pilot Study (Preprint). https://doi.org/10.2196/preprints.51102
Efficacious Web-Based Psychotherapy to Address Depression and Anxiety Among Patients Receiving Oncological and Palliative Care: an Open-Label Randomised Controlled Trial
European Psychiatry / Mar 01, 2023
Alavi, N., Omrani, M., Shirazi, A., Layzell, G., Eadie, J., Jagayat, J., Stephenson, C., Kain, D., Soares, C., & Yang, M. (2023). Efficacious Web-Based Psychotherapy to Address Depression and Anxiety Among Patients Receiving Oncological and Palliative Care: an Open-Label Randomised Controlled Trial. European Psychiatry, 66(S1), S482–S483. https://doi.org/10.1192/j.eurpsy.2023.1032
Developing and Implementing an Online Relapse Prevention Psychotherapy Program for Patients with Alcohol Use Disorder: Protocol for a Randomized Controlled Trial (Preprint)
Nov 30, 2022
Eadie, J., Gutierrez, G., Moghimi, E., Stephenson, C., Khalafi, P., Nikjoo, N., Jagayat, J., Gizzarelli, T., Reshetukha, T., Omrani, M., Yang, M., & Alavi, N. (2022). Developing and Implementing an Online Relapse Prevention Psychotherapy Program for Patients with Alcohol Use Disorder: Protocol for a Randomized Controlled Trial (Preprint). https://doi.org/10.2196/preprints.44694
Determining the Efficacy of Electronic Cognitive Behavioral Therapy for Generalized Anxiety Disorder Compared to Pharmaceutical Interventions: Protocol for a Quasi-Experimental Study
JMIR Research Protocols / May 27, 2021
Alavi, N., Stephenson, C., Yang, M., Shirazi, A., Shao, Y., Kumar, A., Yee, C. S., Miller, S., Stefatos, A., Gholamzadehmir, M., Abbaspour, Z., Patel, A., Patel, C., Reshetukha, T., Omrani, M., & Groll, D. (2021). Determining the Efficacy of Electronic Cognitive Behavioral Therapy for Generalized Anxiety Disorder Compared to Pharmaceutical Interventions: Protocol for a Quasi-Experimental Study. JMIR Research Protocols, 10(5), e27772. https://doi.org/10.2196/27772
Chemogenetic stimulation of a retinal circuit activates brain noradrenergic neurons, prevents apoptosis and suppresses depression-like behaviors
Apr 21, 2021
Bowrey, H. E., James, M. H., Omrani, M., Mohammadkhani, A., & Aston-Jones, G. (2021). Chemogenetic stimulation of a retinal circuit activates brain noradrenergic neurons, prevents apoptosis and suppresses depression-like behaviors. https://doi.org/10.1101/2021.04.20.440684
The 12-Step Approach to Online CBT
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). The 12-Step Approach to Online CBT. Online Cognitive Behavioral Therapy, 11–16. https://doi.org/10.1007/978-3-319-99151-1_2
Action Plans
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). Action Plans. Online Cognitive Behavioral Therapy, 145–156. https://doi.org/10.1007/978-3-319-99151-1_13
What Is the Connection Between Our Thoughts, Feelings, Behaviour, Physical Reactions, and Environment?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Is the Connection Between Our Thoughts, Feelings, Behaviour, Physical Reactions, and Environment? Online Cognitive Behavioral Therapy, 45–57. https://doi.org/10.1007/978-3-319-99151-1_5
What Is Alternative and Balanced Thinking?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Is Alternative and Balanced Thinking? Online Cognitive Behavioral Therapy, 117–130. https://doi.org/10.1007/978-3-319-99151-1_11
What Are Automatic Thoughts?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Are Automatic Thoughts? Online Cognitive Behavioral Therapy, 81–91. https://doi.org/10.1007/978-3-319-99151-1_8
What Is Evidence and How Can It Help Us Rate Our Thoughts and Feeling?
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). What Is Evidence and How Can It Help Us Rate Our Thoughts and Feeling? Online Cognitive Behavioral Therapy, 105–116. https://doi.org/10.1007/978-3-319-99151-1_10
Strategies That Can Be Used in Stressful Situations
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). Strategies That Can Be Used in Stressful Situations. Online Cognitive Behavioral Therapy, 59–67. https://doi.org/10.1007/978-3-319-99151-1_6
Activity Scheduling
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). Activity Scheduling. Online Cognitive Behavioral Therapy, 93–104. https://doi.org/10.1007/978-3-319-99151-1_9
Experiments
Online Cognitive Behavioral Therapy / Dec 28, 2018
Alavi, N., & Omrani, M. (2018). Experiments. Online Cognitive Behavioral Therapy, 131–144. https://doi.org/10.1007/978-3-319-99151-1_12
New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway
Depression and Anxiety / May 10, 2017
Bowrey, H. E., James, M. H., & Aston-Jones, G. (2017). New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway. Depression and Anxiety, 34(7), 588–595. Portico. https://doi.org/10.1002/da.22635
Author response: Distributed task-specific processing of somatosensory feedback for voluntary motor control
Mar 17, 2016
Omrani, M., Murnaghan, C. D., Pruszynski, J. A., & Scott, S. H. (2016). Author response: Distributed task-specific processing of somatosensory feedback for voluntary motor control. https://doi.org/10.7554/elife.13141.012
Independent coding of movement duration in a repetitive non-visually guided movement
Somatosensory & Motor Research / Jan 01, 2006
Motiei-Langroudi, R., Omrani, M., Khoshnoodi, M. A., Pakdel, F. G., Yazdanpanah, E., & Abbassian, A. H. (2006). Independent coding of movement duration in a repetitive non-visually guided movement. Somatosensory & Motor Research, 23(1–2), 19–24. https://doi.org/10.1080/08990220600700834
Resistance of peripheral and sub-cortical somatosensory pathway to electrical noise
Somatosensory & Motor Research / Sep 01, 2004
Omrani, M., Khoshnoodi, M. A., Pakarian, P., Abbassian, A. H., & Shahzadi, S. (2004). Resistance of peripheral and sub-cortical somatosensory pathway to electrical noise. Somatosensory & Motor Research, 21(3–4), 155–158. https://doi.org/10.1080/08990220400012380
Comparing the efficacy of an electronically delivered cognitive behavioural therapy program to a mental health check-in program for generalized anxiety disorder: Protocol for a randomized trial (Preprint)
JMIR Research Protocols / May 10, 2023
Stephenson, C., Kumar, A., Malakouti, N., Nikjoo, N., Jagayat, J., Gizzarelli, T., Patel, C., Gutierrez, G., Shirazi, A., Yang, M., Omrani, M., & Alavi, N. (2023). Comparing the efficacy of an electronically delivered cognitive behavioural therapy program to a mental health check-in program for generalized anxiety disorder: Protocol for a randomized trial (Preprint). JMIR Research Protocols. https://doi.org/10.2196/48899
User Experiences of an Online Therapist-Guided Psychotherapy Platform: A Cross-Sectional Study
Jan 01, 2023
Stephenson, C., Moghimi, E., Gutierrez, G., Jagayat, J., Layzell, G., Patel, C., Omrani, M., & Alavi, N. (2023). User Experiences of an Online Therapist-Guided Psychotherapy Platform: A Cross-Sectional Study. https://doi.org/10.2139/ssrn.4398211
Experience
OPTT Health
Co-founder & CEO / June, 2018 — Present
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