Giuliana Noratto

Food Scientist PhD and Registered Dietician - Texas A&M University

Research Expertise

Food Science

Nutrition

Human Health

Analytical Chemistry

Nutrition and Dietetics

Agronomy and Crop Science

Biotechnology

Cancer Research

Molecular Biology

Drug Discovery

Pharmacology

Clinical Biochemistry

Biochemistry

Endocrinology, Diabetes and Metabolism

Materials Chemistry

Polymers and Plastics

Organic Chemistry

Oncology

Horticulture

Applied Microbiology and Biotechnology

Ecology

Microbiology

Genetics

Animal Science and Zoology

Cell Biology

Biophysics

Molecular Medicine

Physical and Theoretical Chemistry

Pharmaceutical Science

About

Dr. Giuliana Noratto is a senior associate research scientist at Texas A&M AgriLife. She received her Ph.D. in food science and technology from Texas A&M University System, and her M.Sc. in food science and technology from Universidad Nacional Agraria La Molina. She also holds a B.S. in food science and technology from Universidad Nacional Agraria La Molina. Dr. Noratto’s research interests include food safety and quality, sensory science, and food processing.

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Publications

Anticarcinogenic Effects of Polyphenolics from Mango (Mangifera indica) Varieties

Journal of Agricultural and Food Chemistry

2010

Identifying Peach and Plum Polyphenols with Chemopreventive Potential against Estrogen-Independent Breast Cancer Cells

Journal of Agricultural and Food Chemistry

2009

Prebiotic effects of yacon (Smallanthus sonchifolius Poepp. & Endl), a source of fructooligosaccharides and phenolic compounds with antioxidant activity

Food Chemistry

2012

Antioxidant capacity and secondary metabolites in four species of Andean tuber crops: native potato (Solanum sp.), mashua (Tropaeolum tuberosum Ruiz & Pavón), Oca (Oxalis tuberosa Molina) and ulluco (Ullucus tuberosus Caldas)

Journal of the Science of Food and Agriculture

2006

Andean Yacon Root (Smallanthus sonchifolius Poepp. Endl) Fructooligosaccharides as a Potential Novel Source of Prebiotics

Journal of Agricultural and Food Chemistry

2003

Protective Effects of Standardized Pomegranate (Punica granatum L.) Polyphenolic Extract in Ultraviolet-Irradiated Human Skin Fibroblasts

Journal of Agricultural and Food Chemistry

2008

Polyphenolics from Açaí (Euterpe oleracea Mart.) and Red Muscadine Grape (Vitis rotundifolia) Protect Human Umbilical Vascular Endothelial Cells (HUVEC) from Glucose- and Lipopolysaccharide (LPS)-Induced Inflammation and Target MicroRNA-126

Journal of Agricultural and Food Chemistry

2011

Gallotannin derivatives from mango ( Mangifera indica L.) suppress adipogenesis and increase thermogenesis in 3T3-L1 adipocytes in part through the AMPK pathway

Journal of Functional Foods

2018

Anti-lipidaemic and anti-inflammatory effect of açai ( Euterpe oleracea Martius) polyphenols on 3T3-L1 adipocytes

Journal of Functional Foods

2016

HEALTH BENEFITS OF PEACH, NECTARINE AND PLUMS

Acta Horticulturae

2009

Dark sweet cherry (Prunus avium) phenolics enriched in anthocyanins exhibit enhanced activity against the most aggressive breast cancer subtypes without toxicity to normal breast cells

Journal of Functional Foods

2020

Stability of Betacyanin Pigments and Antioxidants in Ayrampo (Opuntia soehrensii Britton and Rose) Seed Extracts and as a Yogurt Natural Colorant

Journal of Food Processing and Preservation

2015

Effect of different fractions of chia (Salvia hispanica L.) on glucose metabolism, in vivo and in vitro

Journal of Functional Foods

2020

Quinoa protective effects against obesity‐induced intestinal inflammation

The FASEB Journal

2015

Probiotics as a Strategy to Improve Overall Human Health in Developing Countries

Journal of Probiotics & Health

2014

Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells

The FASEB Journal

2006

Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD)

The FASEB Journal

2015

Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia

The FASEB Journal

2013

Assessing Cheese Whey Components for Their Potential to Improve Intestinal Health (P06-097-19)

Current Developments in Nutrition

2019

Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice

The FASEB Journal

2015

Aged American Cheddar Cheese as Source of Protein Derived Compounds that Modulate Obese Mice Fecal Bacteria and Colon Inflammation In Vitro

Journal of Nutritional Health & Food Science

2016

Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5)

The FASEB Journal

2014

Quinoa as source of bioactive compounds with potential for intestinal health (647.18)

The FASEB Journal

2014

Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells

The FASEB Journal

2009

Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells

The FASEB Journal

2009

PHENOLICS IN PEACHES AND PLUMS PREFERENTIALLY SUPPRESS THE GROWTH OF ESTROGEN-INDEPENDENT MDA-MB-435 BREAST CANCER CELLS

Acta Horticulturae

2009

Dark Sweet Cherry (Prunus avium) Anthocyanins Inhibited the Growth and Biomarkers for Breast Cancer Growth and Invasion in Highly Metastatic 4T1 Tumor Cells

Current Developments in Nutrition

2021

Dark Sweet Cherry phenolics as Dietary Chemopreventive/therapeutic Compounds for Aggressive Breast Cancer Cell Growth with No Toxicity to Normal Breast Cells (FS13-03-19)

Current Developments in Nutrition

2019

Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity

The FASEB Journal

2015

Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice

The FASEB Journal

2015

The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3)

The FASEB Journal

2014

Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk

The FASEB Journal

2012

MOLECULAR MECHANISMS INVOLVED IN THE INHIBITION OF MDA-MB-435 BREAST CANCER CELLS BY PHENOLIC ACIDS FROM THE RED FLESH PEACH BY00P6653

Acta Horticulturae

2009

Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion

Molecules

2022

Influence of Daily Dark Sweet Cherry (DSC) Juice Consumption for 4 Weeks in Obesity-Associated Inflammation and Cognitive Decline: A Randomized Controlled Trial

Current Developments in Nutrition

2022

Dark Sweet Cherry (DSC) Intake and Cognitive Function in Obese Adults: A Human Clinical Pilot Trial

Journal of the Academy of Nutrition and Dietetics

2021

Anthocyanins Enriched Dark Sweet Cherry (Prunus Avium) Juice Extract Suppressed 4T1 Tumor Cell Growth and Invasive Potential

Journal of the Academy of Nutrition and Dietetics

2021

Calotropis procera Selectively Impaired the 4T1 Breast Cancer Cells Growth by Preferentially Blocking Akt/mTOR Signaling

Current Developments in Nutrition

2021

Dark Sweet Cherry (DSC) Juice Consumption for Obesity-Related Inflammation and Cognitive Function in Obese Adults: A Human Clinical Pilot Trial

Current Developments in Nutrition

2021

Assessment of Whey Functional Ingredients in the Modulation of Fecal Bacteria from Donors with Chronic Gastrointestinal Disease In Vitro

Current Developments in Nutrition

2020

Chemopreventive Potential of DSC Anthocyanins and Total Phenolics Extracted from Dark Sweet Cherry (DSC) Through Modulation of MDA-MB-453 Breast Tumor Proteomic Profile

Current Developments in Nutrition

2020

Dark Sweet Cherry (Prunus Avium L.) Phenolics Induce Apoptosis and Inhibit Invasion on Breast Cancer MDA-MB-453 Through MAPK-dependent and Independent Pathways (P05-007-19)

Current Developments in Nutrition

2019

Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target

The FASEB Journal

2015

Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice

The FASEB Journal

2015

Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12)

The FASEB Journal

2014

Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7)

The FASEB Journal

2014

Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes

The FASEB Journal

2013

Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats

The FASEB Journal

2012

Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a

The FASEB Journal

2011

Phytocomplexes from liquorice (Glycyrrhiza glabra L.) leaves — Chemical characterization and evaluation of their antioxidant, anti-genotoxic and anti-inflammatory activity

Fitoterapia

2011

Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC)

The FASEB Journal

2010

Dark Sweet Cherry (Prunus avium) Supplementation Reduced Blood Pressure and Pro-Inflammatory Interferon Gamma (IFNγ) in Obese Adults without Affecting Lipid Profile, Glucose Levels and Liver Enzymes

Nutrients

2023

Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells

Anti-Cancer Agents in Medicinal Chemistry

2022

The role of dietary polyphenols in osteosarcoma: A possible clue about the molecular mechanisms involved in a process that is just in its infancy

Journal of Food Biochemistry

2021

Jaboticaba (Myrciaria cauliflora) Peel Supplementation Prevents Hepatic Steatosis Through Hypolipidemic Effects and Cholesterol Metabolism Modulation in Diet-Induced Nonalcoholic Fatty Liver Disease Rat Model

Journal of Medicinal Food

2021

Different analysis strategies of 16S rRNA gene data from rodent studies generate contrasting views of gut bacterial communities associated with diet, health and obesity

PeerJ

2020

Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLCγ-1 Downregulation

Nutrition and Cancer

2020

The Impact of Mushroom Polysaccharides on Gut Microbiota and Its Beneficial Effects to Host: A Review

Carbohydrate Polymers

2020

Commercial whey products promote intestinal barrier function with glycomacropeptide enhanced activity in downregulating bacterial endotoxin lipopolysaccharides (LPS)-induced inflammation in vitro

Food & Function

2020

Antitumor potential of dark sweet cherry sweet (Prunus avium) phenolics in suppressing xenograft tumor growth of MDA-MB-453 breast cancer cells

The Journal of Nutritional Biochemistry

2020

Apple consumption is associated with a distinctive microbiota, proteomics and metabolomics profile in the gut of Dawley Sprague rats fed a high-fat diet

PLOS ONE

2019

Quinoa intake reduces plasma and liver cholesterol, lessens obesity-associated inflammation, and helps to prevent hepatic steatosis in obese db/db mouse

Food Chemistry

2019

The Effect of Gluten-Free Diet on Health and the Gut Microbiota Cannot Be Extrapolated from One Population to Others

Nutrients

2018

Dietary Supplementation with Raspberry Extracts Modifies the Fecal Microbiota in Obese Diabetic db/db Mice

Journal of Microbiology and Biotechnology

2018

Non-anthocyanin phenolics in cherry (Prunus avium L.) modulate IL-6, liver lipids and expression of PPARδ and LXRs in obese diabetic (db/db) mice

Food Chemistry

2018

Effect of dark sweet cherry powder consumption on the gut microbiota, short-chain fatty acids, and biomarkers of gut health in obese db/db mice

PeerJ

2018

Effect of barley supplementation on the fecal microbiota, caecal biochemistry, and key biomarkers of obesity and inflammation in obese db/db mice

European Journal of Nutrition

2017

Red raspberry (Rubus idaeus L.) intake decreases oxidative stress in obese diabetic (db/db) mice

Food Chemistry

2017

Red raspberry decreases heart biomarkers of cardiac remodeling associated with oxidative and inflammatory stress in obese diabetic db/db mice

Food & Function

2016

Molecular exploration of fecal microbiome in quinoa-supplemented obese mice

FEMS Microbiology Ecology

2016

Influence of whole-wheat consumption on fecal microbial community structure of obese diabetic mice

PeerJ

2016

Anti-inflammatory activity of polyphenolics from açai (Euterpe oleracea Martius) in intestinal myofibroblasts CCD-18Co cells

Food & Function

2015

Influence of whole-wheat consumption on fecal microbial ecology of obese diabetic mice

Unknown Venue

2015

Consumption of polyphenol-rich peach and plum juice prevents risk factors for obesity-related metabolic disorders and cardiovascular disease in Zucker rats

The Journal of Nutritional Biochemistry

2015

Polyphenolic extracts from cowpea (Vigna unguiculata) protect colonic myofibroblasts (CCD18Co cells) from lipopolysaccharide (LPS)-induced inflammation – modulation of microRNA 126

Food & Function

2015

Pro-Apoptotic Activities of Polyphenolics From Açai (Euterpe oleraceaMartius) in Human SW-480 Colon Cancer Cells

Nutrition and Cancer

2014

Carbohydrate-Free Peach (Prunus persica) and Plum (Prunus domestica) Juice Affects Fecal Microbial Ecology in an Obese Animal Model

PLoS ONE

2014

Assessing non-digestible compounds in apple cultivars and their potential as modulators of obese faecal microbiota in vitro

Food Chemistry

2014

Polyphenolics from peach (Prunus persica var. Rich Lady) inhibit tumor growth and metastasis of MDA-MB-435 breast cancer cells in vivo

The Journal of Nutritional Biochemistry

2014

Potential of tara (Caesalpinia spinosa) gallotannins and hydrolysates as natural antibacterial compounds

Food Chemistry

2014

Technical note: Optimization of lactose quantification based on coupled enzymatic reactions

Journal of Dairy Science

2014

Optimized methodology for the simultaneous extraction of glucosinolates, phenolic compounds and antioxidant capacity from maca (Lepidium meyenii)

Industrial Crops and Products

2013

Micropropagation Effect on the Anti-carcinogenic Activitiy of Polyphenolics from Mexican Oregano (Poliomintha glabrescens Gray) in Human Colon Cancer Cells HT-29

Plant Foods for Human Nutrition

2013

The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis

Molecular Nutrition & Food Research

2013

Standardized curcuminoid extract (Curcuma longa l.) decreases gene expression related to inflammation and interacts with associated microRNAs in human umbilical vein endothelial cells (HUVEC)

Food & Function

2012

Red wine polyphenolics reduce the expression of inflammation markers in human colon-derived CCD-18Co myofibroblast cells: Potential role of microRNA-126

Food & Function

2012

Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: Role of Sp transcription factors and microRNA-27a:ZBTB10

Molecular Carcinogenesis

2012

Flavonol-rich fractions of yaupon holly leaves (Ilex vomitoria, Aquifoliaceae) induce microRNA-146a and have anti-inflammatory and chemopreventive effects in intestinal myofribroblast CCD-18Co cells

Fitoterapia

2011

Effect of genotype, maturity stage and post-harvest storage on phenolic compounds, carotenoid content and antioxidant capacity, of Andean mashua tubers (Tropaeolum tuberosum Ruiz & Pavón)

Journal of the Science of Food and Agriculture

2007

Human Gene Expression as a Tool To Determine Horticultural Maturity in a Bioactive Plant (Echinacea purpurea L. Moench)

Journal of Agricultural and Food Chemistry

2005

Education

Texas A&M University

Texas A&M University System

Ph.D., Department of Food Science and Technology

College Station

Universidad Nacional Agraria La Molina

M.Sc., Food Science and Technology

Lima

Universidad Nacional Agraria La Molina

B.S., Department of Food Science and Technology

Lima

Experience

Texas A&M AgriLife

Senior Associate Research Scientist / August, 2016 — Present

Washington State

Assistant Professor - Head of Food Science lab / 2012 — 2016

Research focus is on the role of nutrition in the prevention or progress of obesity-related chronic diseases. We investigate food bioactive compounds with the main goal of uncovering the molecular mechanisms by which diet derived compounds interact with the genome (effect on gene and protein expression and biomarkers) to shift the onset or outcome of disease. Research projects are centered around: - Milk and dairy-derived bioactive compounds - Plant food botanicals

Texas A&M University

Research Scientist / 2008 — 2012

In charge of projects dealing with effects of natural plant extracts to prevent or cure cancer, diabetes, and cardiovascular complications; all these having in common to be the result of inflammation and obesity.

Links & Social Media

Research Web Site

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