Ramy Ayoub
Research at NotedSource
Research Interests
About
Publications
Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin
Nature Medicine / Jul 27, 2020
Ayoub, R., Ruddy, R. M., Cox, E., Oyefiade, A., Derkach, D., Laughlin, S., Ades-aron, B., Shirzadi, Z., Fieremans, E., MacIntosh, B. J., de Medeiros, C. B., Skocic, J., Bouffet, E., Miller, F. D., Morshead, C. M., & Mabbott, D. J. (2020). Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin. Nature Medicine, 26(8), 1285–1294. https://doi.org/10.1038/s41591-020-0985-2
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
Nature / Sep 21, 2022
Smith, K. S., Bihannic, L., Gudenas, B. L., Haldipur, P., Tao, R., Gao, Q., Li, Y., Aldinger, K. A., Iskusnykh, I. Y., Chizhikov, V. V., Scoggins, M., Zhang, S., Edwards, A., Deng, M., Glass, I. A., Overman, L. M., Millman, J., Sjoboen, A. H., Hadley, J., … Northcott, P. A. (2022). Unified rhombic lip origins of group 3 and group 4 medulloblastoma. Nature, 609(7929), 1012–1020. https://doi.org/10.1038/s41586-022-05208-9
Out of sight, out of mind: mechanisms of social choice in fish
Animal Behaviour / Sep 01, 2019
Ayoub, R., Armstrong, E., & Miller, N. Y. (2019). Out of sight, out of mind: mechanisms of social choice in fish. Animal Behaviour, 155, 163–169. https://doi.org/10.1016/j.anbehav.2019.05.025
Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation
Radiation Research / Jul 16, 2021
Ayoub, R., Lau, K., Yuen, N., Fernandes, D., Elder, M., Yeung, J., Wong, S. C., & Nieman, B. J. (2021). Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation. Radiation Research, 196(4). https://doi.org/10.1667/rade-21-00013.1
QOL-53. METFORMIN RESULTS IN HIPPOCAMPAL REMODELING AND IMPROVED MEMORY ENCODING IN PAEDIATRIC BRAIN TUMOR SURVIVORS TREATED WITH CRANIAL RADIATION: A PILOT RANDOMIZED CONTROLLED CROSSOVER STUDY
Neuro-Oncology / Jun 01, 2018
Ayoub, R., Miller, F., Beera, K., de Medeiros, C., Laughlin, S., Bouffet, E., & Mabbott, D. (2018). QOL-53. METFORMIN RESULTS IN HIPPOCAMPAL REMODELING AND IMPROVED MEMORY ENCODING IN PAEDIATRIC BRAIN TUMOR SURVIVORS TREATED WITH CRANIAL RADIATION: A PILOT RANDOMIZED CONTROLLED CROSSOVER STUDY. Neuro-Oncology, 20(suppl_2), i168–i168. https://doi.org/10.1093/neuonc/noy059.634
MEDB-78. Unified rhombic lip origins of Group 3 and Group 4 medulloblastoma
Neuro-Oncology / Jun 01, 2022
Smith, K., Bihannic, L., Gudenas, B., Gao, Q., Haldipur, P., Tao, R., Iskusnykh, I., Chizhikov, V., Scoggins, M., Zhang, S., Edwards, A., Deng, M., Glass, I., Overman, L., Millman, J., Sjoboen, A., Hadley, J., Mankad, K., Onar-Thomas, A., … Northcott, P. (2022). MEDB-78. Unified rhombic lip origins of Group 3 and Group 4 medulloblastoma. Neuro-Oncology, 24(Supplement_1), i124–i125. https://doi.org/10.1093/neuonc/noac079.452
Behavioral evidence for two distinct memory systems in rats
Animal Cognition / Jun 22, 2022
Miller, N., Ayoub, R., Sentinathan, G., & Mallet, P. E. (2022). Behavioral evidence for two distinct memory systems in rats. Animal Cognition, 25(6), 1599–1608. https://doi.org/10.1007/s10071-022-01645-1
Education
University of Toronto
Ph.D., Medical Biophysics / October, 2023 (anticipated)
Experience
The Hospital for Sick Children
PhD Scientific Researcher / September, 2018 — October, 2023
Designed strategies to limit negative complications experienced by brain tumour survivors treated with radiation; Conducted genetic and pharmacological interventions in mouse models to determine translatability of strategies; Assessed the efficacy of treatment strategies using multi-modal imaging approaches (MRI, serial two-photon imaging); Published findings in peer-reviewed journals Nature, and Radiation Research
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