Work with thought leaders and academic experts from Massachusetts General Hospital

Researchers on NotedSource with connections to Massachusetts General Hospital include Shariq Usmani, PhD, Alex K. Shalek, and Sina Soleymani.

Shariq Usmani, PhD

Boston, Massachusetts, United States of America
Massachusetts General Hospital, Harvard Medical School
Experience

Cabaletta Bio

Scientific Director / 2024Present

I lead a research team in the preclinical R&D organization at Cabaletta bio. I directly manage a talented group of Senior Scientists, Scientists and Research Associates to spearhead and drive innovation in cell therapies and biologics in autoimmune disease indications.

Sana Biotechnology

Principal Scientist / 20222023

As a team lead, I led efforts to establish in vivo genome editing platform, vector design/engineering and optimization, with a broader goal to develop innovative and effective genomic medicine for unmet medical needs.

Zohdan Bio

Consultant / 2024Present

Providing strategic support for all aspects of preclinical, R&D programs in gene therapy, genome editing and virology and immunology space.

Massachusetts General Hospital

Senior Staff Scientist / 20192022

Principal Investigator on an NIH funded grant award to study virus-immune interaction and immune evasion mechanisms. I directed all project aspects including planning, writing, finance/budgeting, and supervision and mentoring of direct reports. Developed a novel multiphoton intravital imaging platform to study virus-immune cell interactions in vivo in lymphoid and mucosal tissues during acute stages of HIV infection.

Research Expertise
Microbiology
Virology
Immunology
Molecular Biology
Genetics
And 5 more
About
Dr. Shariq Usmani is scientific director at Cabaletta bio, a leader in cell therapy for autoimmune diseases (https://www.cabalettabio.com). He leads a research team in preclinical R&D organization at Cabaletta bio. He directly manage a talented group of Senior Scientists, Scientists and Research Associates to spearhead and drive innovation in cell therapies and biologics in autoimmune disease indications. <br> He is also serves as consultant at Zohdan Bio, where he provides strategic support for preclinical R&D programs focused on gene therapy, genome editing, and virology. With a deep foundation in oncology and biologics, Dr. Usmani has led groundbreaking work in both academia and industry, including his tenures at Sana Biotechnology, Harvard Medical School and Massachusetts General Hospital. He's led and spearheaded the development of innovative in vivo genome editing platforms, optimized viral vectors, and engineered cutting-edge reporter assays.

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Alex K. Shalek

J. W. Kieckhefer Professor - IMES, Chemistry, and Koch Institute, MIT; Institute Member, Broad Institute; Member, Ragon Institute
Experience

Broad Institute

Institute Member / July, 2019Present

Associate Member / July, 2014June, 2019

Postdoctoral Fellow - Regev Lab / June, 2011June, 2014

Massachusetts Institute of Technology

J. W. Kieckhefer Professor, Institute for Medical Engineering & Science and Department of Chemistry / July, 2023Present

Extramural Member of the Koch Institute / January, 2018Present

Core Member of the Institute for Medical Engineering & Science / July, 2014Present

Assistant Professor of Chemistry / July, 2014June, 2019

Associate Professor of Chemistry / July, 2019June, 2023

Massachusetts General Hospital

Assistant / July, 2014Present

Harvard-MIT Division of Health Sciences and Technology

Instructor / July, 2014Present

Ragon Institute

Associate Member / July, 2014June, 2018

Member / July, 2018Present

Harvard University

Postdoctoral Fellow - Park Lab / June, 2011June, 2014

Research Expertise
single-cell genomics
micro- and nanotechnology
infectious diseases
cancer
autoimmunity
About
Alex K. Shalek, PhD, is the J. W. Kieckhefer Professor in the Institute for Medical Engineering & Science and the Department of Chemistry, and an Extramural Member of The Koch Institute for Integrative Cancer Research at MIT.  He is also an Institute Member of the Broad Institute, a Member of the Ragon Institute, an Assistant in Immunology at MGB, and an Instructor in Health Sciences & Technology at HMS. Dr. Shalek received his bachelor's degree *summa cum laude* from Columbia University and his Ph.D. from Harvard University in chemical physics under the guidance of Hongkun Park, and performed postdoctoral training under Hongkun Park and Aviv Regev (Broad/MIT). His lab’s research is directed towards the development and application of new approaches to elucidate cellular and molecular features that inform tissue-level function and dysfunction across the spectrum of human health and disease. Dr. Shalek and his work have received numerous honors including a NIH New Innovator Award, a Beckman Young Investigator Award, a Searle Scholar Award, a Pew-Stewart Scholar Award, the Avant-Garde (DP1 Pioneer) Award from the National Institute for Drug Abuse (NIDA), and an Alfred P. Sloan Research Fellowship in Chemistry, as well as the 2019-2020 Harold E. Edgerton Faculty Achievement Award at MIT and the 2020 HMS Young Mentor Award.

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