Work with thought leaders and academic experts from National Centre for Cell Science

I am a devoted cardiovascular research scientist with a keen focus on unraveling the intricate connections between inflammation, immune response, and metabolic dysregulation in both ischemic and non-ischemic heart failure. My passion lies in conceiving innovative hypotheses within cardiovascular medicine and translating them into feasible and actionable solutions, particularly in addressing inflammation through the exploration of Specialized Pro-Resolving Mediators (SPMs) and Pro-Inflammatory Mediators (PIMs) amid risk factors like obesity, diabetes, aging, and cardiotoxic co-medications (oncological drugs). My research delves deeply into four primary areas: comprehensively studying heart failure etiology by integrating insights from splenic leukocytes and cardiac function; quantifying inflammatory mediators hindering cardiac repair while identifying lipid mediators facilitating post-heart attack recovery; elucidating the roles of resolution receptors in inflammation-resolution dynamics within heart failure; and translating our findings into potential human therapies, thoughtfully considering associated risk factors. With over a decade of experience in cardiovascular research, I possess a versatile skill set encompassing mouse models, imaging, flow cytometry, primary cell cultures, histology, molecular biology, and microscopy. Presently, I'm actively engaged in projects exploring the developmental trajectories of Heart Failure with Preserved Ejection Fraction (HFpEF) and investigating the impact of lipoxygenases, specifically 12/15LOX and 5LOX, on acute heart failure across various age groups

Dr. Sandeep Kumar is a contractual senior scientist in the molecular pathology team at Centers for Disease Control and manages the NGS and Bioinformatics facility in the Branch. He is also an Adjunct Assistant Professor in the Department of Biomedical Engineering at the Emory University and Georgia Tech, Atlanta, where he has been a faculty member since 2015. Sandeep completed his Ph.D. at University of Pune, India and his postdoctoral studies at Texas A&M and Emory University. His research interests lie in the area of gene network regulation, ranging from transcription factors, regulatory RNAs (microRNAs and long-noncoding RNAs), with a focus on their role in pathophysiology of cardiovascular diseases, especially atherosclerosis and Cardiomyopathy. In recent years, he has focused on mechanosensitive microRNAs that are regulated by disturbed blood flow in the endothelium.  He is a member of a number of professional organizations including the American Heart Association, the Cellular and Molecular Bioengineering (CMBE) committee, the Chapter Presidents Committee of the Biomedical Engineering Society, the New York Academy of Science, and the American Society of Investigative Pathology. Sandeep has collaborated actively with researchers in several other disciplines, including vascular surgery, biomaterials, nanotechnology, xenograft/tissue engineering, and systems biology. Outside of academics, Sandeep enjoys outdoor activities including camping, hiking, ziplining, and rafting.