Key words: Immunology oncology, Ph.D.,
Research Scientist, Flow cytometry, In
vivo experiments, Translational
research I'm a Ph.D. candidate trained
in immunology and oncology. With 9+
years of research/teaching experience
and 5+ years of clinical experience. I
had 12 high-impact publications with
445+ citations, also 3 more
publications in progress. I'm highly
independent and scientifically
critical with strong
communication/writing skills
(trilingual in English, Mandarin
Chinese and Cantonese) and
collaboration experience. Meanwhile, I
took on roles of ad-hoc peer reviewer
and editorial board member. Years of
lab/clinic training, projects/people
managing, troubleshooting and
collaboration experience made me very
confident of becoming a successful
post-phd research scientist and a
lifelong science explorer. • Project
1: Developed live-Listeria based,
highly-attenuated, oral immunization
cancer vaccine. Evaluating the
immunogenicity and
prophylactic/therapeutic efficacy of
Lm vaccines in mice orthotopic
colorectal cancer models. First author
publication in review. • Project 2:
Worked on how mitochondrial dynamics
and ER stress regulating tumor antigen
presentation and immunogenicity in
solid tumors using pre-clinical models
with a small molecule inhibitor.
Published first author paper on Nature
Communications (IF=16.6). PMCID:
PMC9259736 • Project 3: Worked on
combination of B7-H3 CAR-T therapy and
epigenetic therapy to boost the
anti-tumor efficacy. Published first
author paper on Clinical Cancer
Research (IF=13.8). PMCID: PMC8722110
• Project 4: Studying how retinoic
acid signaling during T cell priming
regulates intestinal CD103+ CD8 TRM
cell formation. Published paper on
Journal of Experimental Medicine
(IF=17.6). PMCID: PMC9960115 • Others:
Designed, Conducted, and Participated
in projects related to anti PD-1/PD-L1
therapy, non-coding RNAs, cancer
biology, molecular biology as an
Assistant Mentor and Project Designer.
Several publications. EB1a Green card
holder. No sponsorship needed. Mobile
number: +16312028917 Email:
Xinyuan.Lei.Immunology@gmail.com I'm
currently actively looking for a
post-phd industry job with graduation
time around February 2025. Please feel
free to connect, message me if you're
interested! I have a lot to offer!
Let's make the world a better place
together.