Work with thought leaders and academic experts from Weizmann Institute of Science

Researchers on NotedSource with connections to Weizmann Institute of Science include Dmitry Batenkov, Ph.D., Aditya Kshirsagar, and Elee Shimshoni.

Aditya Kshirsagar

Memphis, Tennessee, United States of America
St. Jude Children’s Research Hospital
Education

Weizmann Institute of Science

Ph.D., Molecular Genetics and Neuroscience / October, 2022

Rehovot
Research Expertise
Neuroscience
Developmental Biology
RNA biology
Computational biology
Tissue Engineering
And 4 more
About
Aditya Kshirsagar is a highly educated and experienced scientist focused on molecular genetics and neuroscience. He obtained his Ph.D. in Molecular Genetics and Neuroscience from the prestigious Weizmann Institute of Science in 2022. He gained extensive knowledge and expertise in genetics, molecular biology, and neuroscience during his doctoral studies. After completing his Ph.D., Adi joined St Jude Children's Research Hospital as a Postdoctoral Research Associate. Here, he has been involved in cutting-edge research projects, studying the genetic basis of various neurological disorders. He has published several research papers in top scientific journals, making significant contributions to genetics and neuroscience. Adi's passion for understanding the complex mechanisms underlying human diseases has driven him to pursue a research career. He is keen on developing integrated experimental and computational approaches for single-cell and spatial omics to uncover the mechanisms underlying complex neurological conditions and malignancies. He is highly skilled in experimental techniques and has a keen eye for detail, enabling him to design and execute innovative experiments. He is also well-versed in data analysis and interpretation, making him a valuable asset to any research team. His core competencies include embryonic stem cell biology, cortical development, 3D brain organoid models, RNA biology, next-generation sequencing, single-cell biology, multi-omics, and live imaging microscopy techniques. He is also proficient in R and Python programming and experienced in computational pipeline implementation, machine learning & AI, and comprehensive data integration. In addition to his scientific work, Adi is also dedicated to mentoring and teaching the next generation of scientists. He has supervised several master's and undergraduate students, guiding them in their research projects and helping them develop their scientific skills. Overall, Aditya Kshirsagar is a dedicated scientist with a strong background and a track record of excellence in research. His contributions to molecular genetics and neuroscience can potentially significantly impact the diagnosis and treatment of various diseases. Adi is passionate about exploring the potential of cutting-edge technologies and approaches to unravel the mysteries of the human brain and improve patients' lives.

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Elee Shimshoni

Postdoctoral Associate at MIT working on complex human cell models for drug discovery
Education

Weizmann Institute of Science

Ph.D, Life Sciences / August, 2019

Rehovot

Weizmann Institute of Science

M.Sc., Life Sciences / February, 2014

Rehovot

Hebrew University of Jerusalem

B.Sc., Biology, Psychology / August, 2011

Jerusalem
Experience

MIT

Postdoctoral Associate / November, 2022Present

• Developed 2D and 3D primary human cell-based disease models for studying obesity and atherosclerosis. • Trained and mentored research technicians and students on cell culture, molecular biology techniques and experimental design. • Collaborated with chemists and computational biologists to test novel therapeutics and targets using cell-based models.

Harvard University

Postdoctoral Fellow / August, 2019November, 2022

• Led a project aimed at studying the role of the stroma in the progression from Barrett’s Esophagus to Esophageal Cancer, as part of an international collaboration of clinical and academic partners. • Developed two distinct Esophagus Chip models using human primary cells, both containing a 3D stromal compartment: One of the normal esophagus and one of Barrett’s Esophagus. • Collaborated with Emulate, Inc. as a beta user of their new organ-on-a-chip design and provided feedback leading to improvements to the design that was eventually brought to the market. • Advised collaborators on techniques and subject matters within my domains of expertise, including inflammatory bowel disease, extracellular matrix, and organs-on-chips. • Summarized my work at the Ingber Lab in a first-author publication.

Weizmann Institute of Science

Graduate Student / November, 2011August, 2019

• Led a multi-collaborator multidisciplinary team to study and characterize changes in the extracellular matrix that predict colitis, spanning a wide range of analytical approaches. • Authored two first-author publications and a book chapter on extracellular matrix biology in colitis. • Contributed to three other publications in the lab by carrying out imaging, analyses, and writing. • Mentored collaborators and junior students in the lab on animal models, imaging, proteomics, and data analysis techniques, as well as on their English writing skills by reviewing theses and manuscripts.

Research Expertise
extracellular matrix
3D cell culture
inflammation
tumor microenvironment
fibroblasts
And 13 more
About
Elee is a postdoctoral associate at the Department of Chemistry and CSAIL at MIT, working on developing complex cell models for drug discovery. Elee has been studying gastrointestinal diseases for the past 10 years, and is interested in stromal and especially extracellular matrix biology. Elee believes that in order to treat human disease, we must look to the microenvironment for therapeutic targets. Elee is also passionate about science communication and views it as an inseparable part of a scientist's role in society. Currently, she serves as the Scientific Director, and regularly writes for, the non-profit organization "Little, Big Science", which is one of Israel's most popular science communication platforms. Previously, Elee was a postdoc at the Wyss Institute at Harvard University, working on organs-on-chips models for Inflammation and Cancer. Elee received her PhD and my MSc from the Weizmann Institute of Science, where she studies the role of the extracellular matrix in inflammatory bowel disease. Prior to that, Elee received my BSc in Biology and Psychology from the Hebrew University of Jerusalem.

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