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Work with thought leaders and academic experts in Clinical Biochemistry

Companies can greatly benefit from collaborating with experts in Clinical Biochemistry. These researchers bring a deep understanding of the biochemical processes in living organisms and can provide valuable insights and solutions to various challenges. They can contribute to the development of new diagnostic tools, therapies, and treatments for diseases. Additionally, their expertise can help optimize production processes, improve quality control, and ensure regulatory compliance in industries such as pharmaceuticals, biotechnology, and healthcare. By partnering with Clinical Biochemistry researchers, companies can enhance their research and development efforts, drive innovation, and gain a competitive edge in the market.

Researchers on NotedSource with backgrounds in Clinical Biochemistry include Gwendolyn Thomas, Ph.D., CSCS, USAW-L1, Dr. David Siderovski, Ph.D., Aimee Eggler, Dr. Everson A Nunes, Ph.D., Garrett A. Perchetti, Research Scientist - Virology, and Maurice O'Sullivan.

Gwendolyn Thomas, Ph.D., CSCS, USAW-L1

Philadelphia, Pennsylvania, United States of America
Resistance Exercise Physiologist/Performance Enhancement/Optimizing RE Prescription
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (30)
resistance exercise
obesity
breast cancer
chronic disease
inflammation
And 25 more
About
My work has focused on how we can use data to support decisions to individualize monitoring to optimize human performance.  My work has demonstrated that a one size fits all approach is not the way to optimize performance in any setting.  My monitoring approach is one that utilizes a network physiology paradigm, which focuses on nonlinear dynamic interactions. In my athlete monitoring I focus on leveraging EMA and wearables; biological sampling and resistance exercise and conditioning prescribed to elicit a specific biological response.    Additionally, as a practitioner it is important to understand the limitations of athlete monitoring, which is another area research and practice has focused.  This is an important skillset that is currently being utilized by the in a project entitled “Integrating mHealth and Physical Function to Develop a Predictors of Injury and Optimal Performance Model in Special Military Operators “with the Rangers in the 3/75 Ranger Battalion.  This approach is one that quantifies factors such as dosage variables of training and lifestyle factors (sleep, nutrition, life stress).  Using this data, we are working on individualizing acute training sessions to optimize readiness and performance enhancement.   During my time at Syracuse University, I was the professor of record to teach the NSCA CSCS preparation course and lead the strength and conditioning program.  We were developing a master’s in exercise science and I was in the process of working on certification with the NSCA.  We also worked closely with athletics to secure strength and conditioning assistantships to allow for student funding.  I am currently on several NSCA committees, which include the Education and Women’s Committee (next certification cycle).    I am particularly adept at all phases of the athletic performance enhancement and these experiences have given me expertise in evidence based program design, linear and non-linear periodization, exercise endocrinology, resistance exercise physiology and acute and chronic training readiness and non-training parameters
Most Relevant Publications (1+)

51 total publications

Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women

Steroids / Nov 01, 2009

Vingren, J. L., Kraemer, W. J., Hatfield, D. L., Volek, J. S., Ratamess, N. A., Anderson, J. M., Häkkinen, K., Ahtiainen, J., Fragala, M. S., & Thomas, G. A. (2009). Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Steroids, 74(13–14), 1033–1039. https://doi.org/10.1016/j.steroids.2009.08.002

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Dr. David Siderovski, Ph.D.

Fort Worth
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (25)
Regulator of G protein Signaling (RGS) proteins
Pharmacology
Molecular Biology
Cellular and Molecular Neuroscience
Molecular Medicine
And 20 more
About
Dr. David Siderovski is a renowned scientist and academic, with a career spanning over two decades. He received his Ph.D. in Medical Biophysics from the University of Toronto in 1997, where he specialized in signal transduction and cellular signaling pathways. After completing his doctorate, Dr. Siderovski held various faculty positions at prestigious universities, including the University of North Carolina at Chapel Hill, West Virginia University School of Medicine, and the University of North Texas Health Science Center. At these institutions, Dr. Siderovski has made significant contributions to the field of pharmacology through his research on G protein-coupled receptors (GPCRs) and RGS proteins, which are key regulators of GPCR cellular signaling. His work has helped to advance the understanding of RGS proteins and their roles in various diseases, including cancer, cardiovascular disorders, and neurological disorders. In addition to his research, Dr. Siderovski is also a dedicated educator and mentor. He has taught and mentored numerous undergraduate, graduate, and medical students, and has served as a mentor for postdoctoral fellows and junior faculty members. He is known for his passion and enthusiasm for science and his ability to inspire and guide the next generation of scientists. Dr. Siderovski has received numerous awards and honors for his contributions to the scientific community. He was the recipient of the Abel Award in 2004 from the American Society of Pharmacology & Experimental Therapeutics for his pioneering discoveries of the RGS proteins and the GoLoco motif. He has also served on editorial boards of several scientific journals (including a decade at *J.Biol.Chem.*) and has been a member of various scientific committees, NIH study section panels, and pharma/biotech advisory boards, including for Inspire, Wyeth, and BellBrook Labs. Overall, Dr. David Siderovski is a highly accomplished and respected scientist and educator, whose research has had a significant impact on the field of pharmacology. His dedication and passion for science continue to inspire and influence the next generation of researchers in this field.
Most Relevant Publications (1+)

94 total publications

G protein signaling in the parasite Entamoeba histolytica

Experimental & Molecular Medicine / Mar 22, 2013

Bosch, D. E., & Siderovski, D. P. (2013). G protein signaling in the parasite Entamoeba histolytica. Experimental & Molecular Medicine, 45(3), e15–e15. https://doi.org/10.1038/emm.2013.30

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Aimee Eggler

Villanova, Pennsylvania, United States of America
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (18)
Biochemistry
Physiology (medical)
Toxicology
Organic Chemistry
Drug Discovery
And 13 more
About
Dr. Eggler has 20 years of experience in the field of redox biology, with a focus on the Nrf2 transcription factor, a master regulator of antioxidant, detoxification and anti-inflammatory genes. She is also an award-winning educator and the recipient of the Villanova University Junior Faculty Excellence in Teaching award. Her interests in education include innovation in teaching metabolism from a logic-based perspective.
Most Relevant Publications (1+)

25 total publications

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013

Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112

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Dr. Everson A Nunes, Ph.D.

Hamilton, Ontario, Canada
Post-Doctoral Fellow at McMaster University | former Associate Professor - Physiological Sciences
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (39)
skeletal muscle
nutrition
physical activity
obesity
cancer
And 34 more
About
Dr. Everson A Nunes is a highly accomplished researcher and educator in the field of physiological sciences. He received his Ph.D. in Cellular and Molecular Biology with a focus on Physiological Sciences from Universidade Federal do Paraná in 2009, after completing a BSc in Human Nutrition and an MSc in Physiological Sciences. He also holds a specialization in Exercise Physiology and a BSc in Biological Sciences from Universidade Federal do Paraná. Dr. Nunes has a strong background in research, having completed two post-doctoral fellowships at McMaster University and Universidade Federal do Paraná. He has also held positions as an associate professor and assistant professor at Universidade Federal de Santa Catarina. He has published numerous articles in peer-reviewed journals, and his research focuses on the effects of exercise and nutrition on physiological processes in the human body. In addition to his research, Dr. Nunes is also a dedicated educator. He has taught at various universities in Brazil, including Universidade Federal de Santa Catarina, Universidade Gama Filho, Faculdades Integradas Espírita, Pontificia Universidade Católica do Paraná, and Faculdade do Litoral Sul. He is known for his dynamic teaching style and his ability to engage students in complex physiological concepts. Dr. Nunes is a member of several professional organizations, including the American Society for Nutrition, the Canadian Society of Exercise Physiology, the Canadian Nutrition Society and the Brazilian Society of Physiology. He is also a regular speaker at national and international conferences, sharing his expertise and research findings with colleagues and students. Overall, Dr. Nunes is a highly qualified and experienced professional in physiological sciences, metabolism, cancer and nutrition. His dedication to research and education makes him a valuable asset to any institution.
Most Relevant Publications (10+)

97 total publications

Low fish oil intake improves insulin sensitivity, lipid profile and muscle metabolism on insulin resistant MSG-obese rats

Lipids in Health and Disease / Jan 01, 2011

Yamazaki, R. K., Brito, G. A., Coelho, I., Pequitto, D. C., Yamaguchi, A. A., Borghetti, G., Schiessel, D., Kryczyk, M., Machado, J., Rocha, R. E., Aikawa, J., Iagher, F., Naliwaiko, K., Tanhoffer, R. A., Nunes, E. A., & Fernandes, L. (2011). Low fish oil intake improves insulin sensitivity, lipid profile and muscle metabolism on insulin resistant MSG-obese rats. Lipids in Health and Disease, 10(1), 66. https://doi.org/10.1186/1476-511x-10-66

Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats

Lipids in Health and Disease / Oct 16, 2013

Iagher, F., de Brito Belo, S. R., Souza, W. M., Nunes, J. R., Naliwaiko, K., Sassaki, G. L., Bonatto, S. J. R., de Oliveira, H. H. P., Brito, G. A. P., de Lima, C., Kryczyk, M., de Souza, C. F., Steffani, J. A., Nunes, E. A., & Fernandes, L. C. (2013). Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats. Lipids in Health and Disease, 12(1). https://doi.org/10.1186/1476-511x-12-146

Nitrate consumption preserves HFD-induced skeletal muscle mitochondrial ADP sensitivity and lysine acetylation: A potential role for SIRT1

Redox Biology / Jun 01, 2022

Brunetta, H. S., Petrick, H. L., Momken, I., Handy, R. M., Pignanelli, C., Nunes, E. A., Piquereau, J., Mericskay, M., & Holloway, G. P. (2022). Nitrate consumption preserves HFD-induced skeletal muscle mitochondrial ADP sensitivity and lysine acetylation: A potential role for SIRT1. Redox Biology, 52, 102307. https://doi.org/10.1016/j.redox.2022.102307

Impact of combined long-term fructose and prednisolone intake on glucose and lipid homeostasis in rats: benefits of intake interruption or fish oil administration

The Journal of Nutritional Biochemistry / Apr 01, 2021

Santos, C. dos, da Silva, J. S., Brunetta, H. S., Chagas, T. R., Zoccal, D. B., Nunes, E. A., & Rafacho, A. (2021). Impact of combined long-term fructose and prednisolone intake on glucose and lipid homeostasis in rats: benefits of intake interruption or fish oil administration. The Journal of Nutritional Biochemistry, 90, 108572. https://doi.org/10.1016/j.jnutbio.2020.108572

Does l-leucine supplementation cause any effect on glucose homeostasis in rodent models of glucose intolerance? A systematic review

Amino Acids / Sep 27, 2018

Brunetta, H. S., de Camargo, C. Q., & Nunes, E. A. (2018). Does l-leucine supplementation cause any effect on glucose homeostasis in rodent models of glucose intolerance? A systematic review. Amino Acids, 50(12), 1663–1678. https://doi.org/10.1007/s00726-018-2658-8

Implications of Palmitoleic Acid (Palmitoleate) On Glucose Homeostasis, Insulin Resistance and Diabetes

Current Drug Targets / Mar 30, 2017

Nunes, E., & Rafacho, A. (2017). Implications of Palmitoleic Acid (Palmitoleate) On Glucose Homeostasis, Insulin Resistance and Diabetes. Current Drug Targets, 18(6), 619–628. https://doi.org/10.2174/1389450117666151209120345

Relationship between Acute Phase Proteins and Serum Fatty Acid Composition in Morbidly Obese Patients

Disease Markers / Jan 01, 2013

Fernandes, R., Beserra, B. T. S., Cunha, R. S. G., Hillesheim, E., Camargo, C. de Q., Pequito, D. C. T., de Castro, I. C., Fernandes, L. C., Nunes, E. A., & Trindade, E. B. S. de M. (2013). Relationship between Acute Phase Proteins and Serum Fatty Acid Composition in Morbidly Obese Patients. Disease Markers, 35, 105–112. https://doi.org/10.1155/2013/913715

Lymphocytes transfer [14C]‐labeled fatty acids to skeletal muscle in culture; modulation by exercise

Cell Biochemistry and Function / May 26, 2010

Brito, G. A. P., Nunes, E. A., Nogata, C., Yamazaky, R. K., Naliwaiko, K., Curi, R., & Fernandes, L. C. (2010). Lymphocytes transfer [14C]‐labeled fatty acids to skeletal muscle in culture; modulation by exercise. Cell Biochemistry and Function, 28(4), 278–282. Portico. https://doi.org/10.1002/cbf.1652

Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation

Prostaglandins, Leukotrienes and Essential Fatty Acids / Feb 01, 2007

Mund, R. C., Pizato, N., Bonatto, S., Nunes, E. A., Vicenzi, T., Tanhoffer, R., de Oliveira, H. H. P., Curi, R., Calder, P. C., & Fernandes, L. C. (2007). Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins, Leukotrienes and Essential Fatty Acids, 76(2), 113–120. https://doi.org/10.1016/j.plefa.2006.11.008

The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle

Molecular and Cellular Biochemistry / May 01, 2005

Yamazaki, R. K., Hirabara, S. M., Tchaikovski, O., Lopes, M. C. P., Nogata, C., Aikawa, J., Nunes, E. A., Tanhoffer, R. A., Lissa, M. D., & Fernandes, L. C. (2005). The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle. Molecular and Cellular Biochemistry, 273(1–2), 145–150. https://doi.org/10.1007/s11010-005-8265-5

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Garrett A. Perchetti, Research Scientist - Virology

New York
Research Scientist and MD Candidate in virology with publications on infectious diseases, laboratory medicine, viral genetics, and clinical medicine
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (14)
Virology
Microbiology
Infectious Diseases
SARS-CoV-2
COVID-19
And 9 more
About
Garrett A. Perchetti is a highly accomplished research scientist in the field of virology. He received a Bachelor of Science in Microbiology and a Bachelor of Arts in Art History from the University of Washington. His interest in both science and the arts led him to pursue a career in virology, where he could combine his passion for understanding the natural world with his creative thinking skills. After completing his undergraduate studies, Garrett continued his education by earning a Medical Degree from Ross University School of Medicine in 2025. During his time in medical school, he developed a keen interest in virology and infectious diseases, which ultimately led him to specialize in this field. Garrett's educational background is complemented by his extensive experience as a research scientist. He has worked at the University of Washington School of Medicine, where he has conducted groundbreaking research on various types of viruses. His work has been published in numerous scientific journals, and he has presented his findings at international conferences. Garrett's contributions to the field of virology have been widely recognized, and he has received several awards and accolades for his work. He is known for his meticulous attention to detail, innovative thinking, and ability to collaborate effectively with other researchers. In his free time, Garrett enjoys painting, hiking, and traveling. He is also passionate about raising awareness about the importance of vaccinations and promoting public health initiatives. With his exceptional education and extensive experience, Garrett A. Perchetti is a valuable asset to the field of virology and will continue to make significant contributions in the future.
Most Relevant Publications (1+)

28 total publications

Metagenomic Analysis Reveals Clinical SARS-CoV-2 Infection and Bacterial or Viral Superinfection and Colonization

Clinical Chemistry / Jun 12, 2020

Peddu, V., Shean, R. C., Xie, H., Shrestha, L., Perchetti, G. A., Minot, S. S., Roychoudhury, P., Huang, M.-L., Nalla, A., Reddy, S. B., Phung, Q., Reinhardt, A., Jerome, K. R., & Greninger, A. L. (2020). Metagenomic Analysis Reveals Clinical SARS-CoV-2 Infection and Bacterial or Viral Superinfection and Colonization. Clinical Chemistry, 66(7), 966–972. https://doi.org/10.1093/clinchem/hvaa106

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Maurice O'Sullivan

Cork
University College Cork, School of Food and Nutritional Sciences
Most Relevant Research Expertise
Clinical Biochemistry
Other Research Expertise (33)
sensory
meat
dairy
consumer
Food Science
And 28 more
About
Dr. Maurice O’ Sullivan is a sensory scientist and senior lecturer in food science working in the School of Food and Nutritional Sciences, UCC. In the past Maurice has worked in the food industry as a sensory scientist and flavour chemist for Diageo Baileys and Guinness. He has worked as a food technologist and process/product development scientist for the processed foods sector in the 1990’s as well as more recently a product development consultant to the dairy, meat and beverage industries. He has a Ph.D. in Sensory and Consumer science from the Department of Food Science, University of Copenhagen, Denmark as well as MSc. and BSc. Degrees in Food Science and Technology from University College Cork (UCC). Currently Maurice works in the School of Food and Nutritional Sciences, University College Cork as a senior lecturer and sensory and product reformulation project coordinator on large scale multi-million euro research projects. For many years he has also managed the “Sensory Unit” at UCC working on sensory and flavour based projects involving a diverse selection of products. This sensory science based service (at UCC) includes testing the difference, affective and descriptive analysis of foods and beverages as well as assessing shelf-life and comparing sensory results to microbiological and analytical (instrumental, physic-chemical) data using multivariate data analysis (MVA). Sensory testing is critical for new product development/optimisation, ingredient substitution and devising appropriate packaging and comparing foods or beverages to competitor’s products. Again, the key to unlocking the hidden secrets of this multimodal data is with MVA (Multivariate Data Analysis). To date Maurice has secured significant research funding of €5,300,000 Gross, €3,843,329.30 to UCC. He has worked in the area of targeted ingredient (salt, fat, sugar) reduction in foods since 1997. The focus of this research has been reduction of negative ingredients linked to civilisation diseases (Diabetes, Obesity, Heart Disease, Anaemia) while maintaining sensory properties, but also improving nutritional quality of developed products. To date this research has produced numerous publications with many more in development. Other research areas include Cross Cultural Sensory Perception of Irish Dairy Products in Asia, Europe and North America as well as Foods for the Elderly, Packaging and Meat optimisation. Maurice has published more than 200 sensory or consumer research based articles (papers, book chapters, proceedings etc.).
Most Relevant Publications (1+)

85 total publications

Correlating Volatile Lipid Oxidation Compounds with Consumer Sensory Data in Dairy Based Powders during Storage

Antioxidants / Apr 20, 2020

Clarke, H. J., O’Sullivan, M. G., Kerry, J. P., & Kilcawley, K. N. (2020). Correlating Volatile Lipid Oxidation Compounds with Consumer Sensory Data in Dairy Based Powders during Storage. Antioxidants, 9(4), 338. https://doi.org/10.3390/antiox9040338

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Example Clinical Biochemistry projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Clinical Biochemistry?

Development of Novel Biomarkers

A Clinical Biochemistry expert can collaborate with a company to identify and validate novel biomarkers for early disease detection. This can lead to the development of diagnostic tests that are more accurate, sensitive, and specific, enabling early intervention and improved patient outcomes.

Drug Discovery and Development

Collaborating with a Clinical Biochemistry researcher can accelerate the drug discovery and development process. Their expertise in understanding the biochemical mechanisms of diseases can help identify potential drug targets and design effective therapeutic interventions.

Optimization of Production Processes

Clinical Biochemistry researchers can optimize production processes in industries such as pharmaceuticals and biotechnology. By studying the biochemical reactions involved in manufacturing, they can improve efficiency, reduce costs, and ensure the production of high-quality products.

Quality Control and Assurance

Companies can benefit from the expertise of Clinical Biochemistry researchers in implementing robust quality control and assurance measures. They can develop and validate analytical methods, perform rigorous testing, and ensure compliance with regulatory standards, thereby enhancing product safety and reliability.

Personalized Medicine

Collaboration with Clinical Biochemistry experts can enable the development of personalized medicine approaches. By analyzing an individual's biochemical profile, researchers can tailor treatments and therapies to specific patient characteristics, leading to improved efficacy and reduced side effects.