Work with thought leaders and academic experts in Biochemistry

Companies can greatly benefit from working with experts in the field of Biochemistry. These researchers bring a deep understanding of molecular processes, biochemical reactions, and the structure and function of biomolecules. They can provide valuable insights and solutions for various industries, including pharmaceuticals, biotechnology, agriculture, food science, and environmental science. By collaborating with Biochemistry experts, companies can enhance their research and development efforts, accelerate innovation, improve product quality, optimize production processes, and address complex challenges. Their expertise can also contribute to the discovery of new drugs, the development of sustainable technologies, and the improvement of health and well-being.

Researchers on NotedSource with backgrounds in Biochemistry include Ping Luo, Gwendolyn Thomas, Ph.D., CSCS, USAW-L1, Luciano Dibona, Ph.D, Ajay Badhan, Dr. David Siderovski, Ph.D., Martin Tsui, Boris Leibovitch, Dushani L. Palliyaguru, Ph.D., Daniel Milej, Ph.D., Edward Elliott, Ph.D., Burcu Vitrinel, Ph.D., Elvira Forte, Shariq Usmani, PhD, and David Proctor.

Ping Luo

Toronto, Ontario, Canada
8 Years Experience
Assistant Professor at Algoma University
Education

University of Saskatchewan

Ph.D., Biomedical Engineering / September, 2019

Saskatoon, Saskatchewan, Canada

Beijing Institute of Technology

M.Eng., Biomedical Engineering / June, 2015

Beijing

Hunan University

B.Eng., Computer Science / June, 2010

Changsha
Experience

Princess Margaret Cancer Centre

Postdoctoral Researcher / November, 2019 — Present

I work in Dr. Trevor Pugh's lab and design cancer diagnosis and treatment strategies by analyze cell-free DNA and single cell sequencing data

Princess Margaret Cancer Centre

Bioinformatics Specialist / September, 2023 — Present

I work in Dr. Tak Mak's lab and study tumor immunology using single cell and TCR sequencing data.

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (21)
single-cell genomics
deep learning
complex network analysis
Genetics (clinical)
Genetics
And 16 more
About
8 years of science and engineering experience integrating multi-omics data to identify biomarkers for cancer studies. Seeking to apply data analytics expertise to develop new diagnosis and treatment strategies.
Most Relevant Publications (6+)

23 total publications

Enhancing the prediction of disease–gene associations with multimodal deep learning

Bioinformatics / Mar 02, 2019

Luo, P., Li, Y., Tian, L.-P., & Wu, F.-X. (2019). Enhancing the prediction of disease–gene associations with multimodal deep learning. Bioinformatics, 35(19), 3735–3742. https://doi.org/10.1093/bioinformatics/btz155

Identifying cell types from single-cell data based on similarities and dissimilarities between cells

BMC Bioinformatics / May 01, 2021

Li, Y., Luo, P., Lu, Y., & Wu, F.-X. (2021). Identifying cell types from single-cell data based on similarities and dissimilarities between cells. BMC Bioinformatics, 22(S3). https://doi.org/10.1186/s12859-020-03873-z

Ensemble disease gene prediction by clinical sample-based networks

BMC Bioinformatics / Mar 01, 2020

Luo, P., Tian, L.-P., Chen, B., Xiao, Q., & Wu, F.-X. (2020). Ensemble disease gene prediction by clinical sample-based networks. BMC Bioinformatics, 21(S2). https://doi.org/10.1186/s12859-020-3346-8

A Novel Core-Attachment-Based Method to Identify Dynamic Protein Complexes Based on Gene Expression Profiles and PPI Networks

PROTEOMICS / Feb 20, 2019

Xiao, Q., Luo, P., Li, M., Wang, J., & Wu, F.-X. (2019). A Novel Core-Attachment-Based Method to Identify Dynamic Protein Complexes Based on Gene Expression Profiles and PPI Networks. PROTEOMICS, 19(5), 1800129. Portico. https://doi.org/10.1002/pmic.201800129

Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma

Blood / Nov 05, 2021

Coffey, D. G., Maura, F., Gonzalez-Kozlova, E., Diaz-Mejia3, J., Luo, P., Zhang, Y., Xu, Y., Warren, E. H., Smith, E. L., Cho, H. J., Lesokhin, A., Diamond, B., Kazandjian, D., Pugh, T. J., Green, D. J., Gnjatic, S., & Landgren, O. (2021). Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma. Blood, 138(Supplement 1), 329–329. https://doi.org/10.1182/blood-2021-154506

Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets

Computational and Structural Biotechnology Journal / Jan 01, 2022

Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029

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Gwendolyn Thomas, Ph.D., CSCS, USAW-L1

Philadelphia, Pennsylvania, United States of America
17 Years Experience
Resistance Exercise Physiologist/Performance Enhancement/Optimizing RE Prescription
Education

University of Connecticut

Ph.D., Kinesiology (Exercise Endocrinology, Exercise Physiology, Resistance Exercise) / May, 2010

Storrs, Connecticut, United States of America

University of Connecticut

M.A., Strength and Conditioning / May, 2007

Storrs, Connecticut, United States of America
Experience

Penn State University

Assistant Research Professor / September, 2019 — August, 2023

Principal Investigator of the Exercise Prescription Lab. The lab (PI: Thomas) conducts interdisciplinary and translational research on chronic diseases, publishing in peer-reviewed journals. Transform population health outcomes through data, analytics, and actionable insights. Chair the regulatory review board, overseeing IRB Administration, running meetings, and approving research protocols. Expertise in institutional, FDA, and Federal regulatory work.

Penn State Integrative Physiology

Faculty Member / September, 2019 — Present

Faculty Member In Integrative Physiology

Syracuse University

Assistant Professor / August, 2016 — August, 2019

Independent Principal Investigator: Assumed responsibility for all research studies conducted in my lab, including but not limited to oversight and training of research assistants (25), training of research assistants (30), and generating independent, high quality, reproducible results. Responsible for the management and integrity of design, conduct and reporting of the research project and for managing, monitoring and ensuring the integrity of collaborative relationships. Curriculum Committee Chair:Led Curriculum Committee and Departmental Leadership to develop Master’s Degree in Strength and Conditioning through certifying agency, the National Strength and Conditioning Association (NSCA).

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (30)
resistance exercise
obesity
breast cancer
chronic disease
inflammation
And 25 more
About
My work has focused on how we can use data to support decisions to individualize monitoring to optimize human performance.  My work has demonstrated that a one size fits all approach is not the way to optimize performance in any setting.  My monitoring approach is one that utilizes a network physiology paradigm, which focuses on nonlinear dynamic interactions. In my athlete monitoring I focus on leveraging EMA and wearables; biological sampling and resistance exercise and conditioning prescribed to elicit a specific biological response.    Additionally, as a practitioner it is important to understand the limitations of athlete monitoring, which is another area research and practice has focused.  This is an important skillset that is currently being utilized by the in a project entitled “Integrating mHealth and Physical Function to Develop a Predictors of Injury and Optimal Performance Model in Special Military Operators “with the Rangers in the 3/75 Ranger Battalion.  This approach is one that quantifies factors such as dosage variables of training and lifestyle factors (sleep, nutrition, life stress).  Using this data, we are working on individualizing acute training sessions to optimize readiness and performance enhancement.   During my time at Syracuse University, I was the professor of record to teach the NSCA CSCS preparation course and lead the strength and conditioning program.  We were developing a master’s in exercise science and I was in the process of working on certification with the NSCA.  We also worked closely with athletics to secure strength and conditioning assistantships to allow for student funding.  I am currently on several NSCA committees, which include the Education and Women’s Committee (next certification cycle).    I am particularly adept at all phases of the athletic performance enhancement and these experiences have given me expertise in evidence based program design, linear and non-linear periodization, exercise endocrinology, resistance exercise physiology and acute and chronic training readiness and non-training parameters
Most Relevant Publications (2+)

51 total publications

Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women

Steroids / Nov 01, 2009

Vingren, J. L., Kraemer, W. J., Hatfield, D. L., Volek, J. S., Ratamess, N. A., Anderson, J. M., Häkkinen, K., Ahtiainen, J., Fragala, M. S., & Thomas, G. A. (2009). Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Steroids, 74(13–14), 1033–1039. https://doi.org/10.1016/j.steroids.2009.08.002

Endogenous opioid peptide responses to opioid and anti-inflammatory medications following eccentric exercise-induced muscle damage

Peptides / Jan 01, 2010

Kraemer, W. J., Joseph, M. F., Volek, J. S., Hoffman, J. R., Ratamess, N. A., Newton, R. U., Fragala, M. S., French, D. N., Rubin, M. A., Scheett, T. P., McGuigan, M. R., Thomas, G. A., Gomez, A. L., Häkkinen, K., & Maresh, C. M. (2010). Endogenous opioid peptide responses to opioid and anti-inflammatory medications following eccentric exercise-induced muscle damage. Peptides, 31(1), 88–93. https://doi.org/10.1016/j.peptides.2009.09.031

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Luciano Dibona, Ph.D

Santiago
7 Years Experience
Highly motivated young professional with a PhD in Chemistry and specialized in Photobiological aspects of Life Sciences and Agriculture on Crop protection.
Education

Pontificia Universidad Católica de Chile

PhD Chemistry, Facultad de Química y de Farmacia

Santiago

Universidad de Tarapaca - Campus Saucache

Químico/Licenciado en Química, Departamento de Química

Arica
Experience

IQS

Postdoctoral Researcher / March, 2022 — Present

Pontificia Universidad Católica de Chile

R+D Project Director / January, 2021 — April, 2023

R&D Project director in VIU Project: “Development of fungicidal formulations based on photoactive polymers (LEAPs) for application in Agriculture”. Pontificia Universidad Católica de Chile.

Pontificia Universidad Católica de Chile

Researcher / January, 2021 — June, 2023

Researcher in COPEC UC 2019.J.1273 “Photoactive biofungicides for use citrus and postharvest table grapes” Pontificia Universidad Católica de Chile

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (5)
Antimicrobial Photodynamic Therapy
Physical and Theoretical Chemistry
Plant Science
Horticulture
Photobiology
About
With more than 5 years of background in the field, I'm committed to drive scientific advances into impactful innovation for the industry and the market through knowledge and technology transfer. Experience as a consultant in formulation of R&D projects with a focus on teamwork, collaboration, and communication skills. Works with an analytical mindset to deliver meaningful results. Experience in designing and evaluating industry-driven scientific research and intellectual property protection processes involved.
Most Relevant Publications (1+)

7 total publications

Recent Photosensitizer Developments, Delivery Strategies and Combination‐based Approaches for Photodynamic Therapy†

Photochemistry and Photobiology / Dec 20, 2022

Mariño‐Ocampo, N., Dibona‐Villanueva, L., Escobar‐Álvarez, E., Guerra‐Díaz, D., Zúñiga‐Núñez, D., Fuentealba, D., & Robinson‐Duggon, J. (2022). Recent Photosensitizer Developments, Delivery Strategies and Combination‐based Approaches for Photodynamic Therapy†. Photochemistry and Photobiology, 99(2), 469–497. Portico. https://doi.org/10.1111/php.13749

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Ajay Badhan

Lethbridge, Alberta, Canada
15 Years Experience
Research Biologist, Lethbridge Research Center, Canada
Education

Ph.D., Microbiology

Experience

Agriculture Agri-food Canada

Biologist / May, 2015 — Present

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (26)
Animal nutrition
cell wall biosynthesis and its deconstruction
biofuels
Waste Management and Disposal
Renewable Energy, Sustainability and the Environment
And 21 more
About
I am a proficient researcher with valuable research and teaching experience acquired at distinguished institutes like Complex Carbohydrate Research Center, US, University of Alberta, Canada, and Lethbridge Research Center (AAFC), Canada. I have been working for past 15 years on multiple projects focused on the economical, environmental and social sustainability of agricultural production. Improvement in livestock performance, productivity, and health by unlocking the microbiome, development of clean technologies, improving agriculture environmental performance, and Increase agro-ecosystem resilience are prime objectives for my research.
Most Relevant Publications (2+)

29 total publications

Functionally diverse multiple xylanases of thermophilic fungus Myceliophthora sp. IMI 387099

Enzyme and Microbial Technology / Oct 01, 2004

Badhan, A. K., Chadha, B. S., Sonia, K. G., Saini, H. S., & Bhat, M. K. (2004). Functionally diverse multiple xylanases of thermophilic fungus Myceliophthora sp. IMI 387099. Enzyme and Microbial Technology, 35(5), 460–466. https://doi.org/10.1016/j.enzmictec.2004.07.002

Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses

Computational and Structural Biotechnology Journal / Jan 01, 2022

Badhan, A., Low, K. E., Jones, D. R., Xing, X., Milani, M. R. M., Polo, R. O., Klassen, L., Venketachalam, S., Hahn, M. G., Abbott, D. W., & McAllister, T. A. (2022). Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses. Computational and Structural Biotechnology Journal, 20, 148–164. https://doi.org/10.1016/j.csbj.2021.12.009

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Dr. David Siderovski, Ph.D.

Fort Worth
25 Years Experience
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Education

University of Toronto

Ph.D., Medical Biophysics / November, 1997

Toronto, Ontario, Canada
Experience

University of North Carolina at Chapel Hill

Professor / January, 1999 — June, 2012

West Virginia University School of Medicine

E.J. Van Liere Endowed Medicine Professor and Chairman / July, 2012 — February, 2020

Chair of the Dept. of Physiology and Pharmacology

University of North Texas Health Science Center

Professor & Chair / March, 2020 — Present

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (25)
Regulator of G protein Signaling (RGS) proteins
Pharmacology
Molecular Biology
Cellular and Molecular Neuroscience
Molecular Medicine
And 20 more
About
Dr. David Siderovski is a renowned scientist and academic, with a career spanning over two decades. He received his Ph.D. in Medical Biophysics from the University of Toronto in 1997, where he specialized in signal transduction and cellular signaling pathways. After completing his doctorate, Dr. Siderovski held various faculty positions at prestigious universities, including the University of North Carolina at Chapel Hill, West Virginia University School of Medicine, and the University of North Texas Health Science Center. At these institutions, Dr. Siderovski has made significant contributions to the field of pharmacology through his research on G protein-coupled receptors (GPCRs) and RGS proteins, which are key regulators of GPCR cellular signaling. His work has helped to advance the understanding of RGS proteins and their roles in various diseases, including cancer, cardiovascular disorders, and neurological disorders. In addition to his research, Dr. Siderovski is also a dedicated educator and mentor. He has taught and mentored numerous undergraduate, graduate, and medical students, and has served as a mentor for postdoctoral fellows and junior faculty members. He is known for his passion and enthusiasm for science and his ability to inspire and guide the next generation of scientists. Dr. Siderovski has received numerous awards and honors for his contributions to the scientific community. He was the recipient of the Abel Award in 2004 from the American Society of Pharmacology & Experimental Therapeutics for his pioneering discoveries of the RGS proteins and the GoLoco motif. He has also served on editorial boards of several scientific journals (including a decade at *J.Biol.Chem.*) and has been a member of various scientific committees, NIH study section panels, and pharma/biotech advisory boards, including for Inspire, Wyeth, and BellBrook Labs. Overall, Dr. David Siderovski is a highly accomplished and respected scientist and educator, whose research has had a significant impact on the field of pharmacology. His dedication and passion for science continue to inspire and influence the next generation of researchers in this field.
Most Relevant Publications (24+)

94 total publications

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

Nature Structural Biology / May 13, 2002

Snyder, J. T., Worthylake, D. K., Rossman, K. L., Betts, L., Pruitt, W. M., Siderovski, D. P., Der, C. J., & Sondek, J. (2002). Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nature Structural Biology, 9(6), 468–475. https://doi.org/10.1038/nsb796

RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity

Journal of Biological Chemistry / Aug 01, 2001

Kimple, R. J., De Vries, L., Tronchère, H., Behe, C. I., Morris, R. A., Farquhar, M. G., & Siderovski, D. P. (2001). RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity. Journal of Biological Chemistry, 276(31), 29275–29281. https://doi.org/10.1074/jbc.m103208200

GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain

Journal of Biological Chemistry / Jul 01, 1998

Snow, B. E., Hall, R. A., Krumins, A. M., Brothers, G. M., Bouchard, D., Brothers, C. A., Chung, S., Mangion, J., Gilman, A. G., Lefkowitz, R. J., & Siderovski, D. P. (1998). GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain. Journal of Biological Chemistry, 273(28), 17749–17755. https://doi.org/10.1074/jbc.273.28.17749

Return of the GDI: The GoLoco Motif in Cell Division

Annual Review of Biochemistry / Jun 01, 2004

Willard, F. S., Kimple, R. J., & Siderovski, D. P. (2004). Return of the GDI: The GoLoco Motif in Cell Division. Annual Review of Biochemistry, 73(1), 925–951. https://doi.org/10.1146/annurev.biochem.73.011303.073756

The GoLoco motif: a Gαi/o binding motif and potential guanine-nucleotide exchange factor

Trends in Biochemical Sciences / Sep 01, 1999

Siderovski, D. P., Diversé-Pierluissi, M. A., & De Vries, L. (1999). The GoLoco motif: a Gαi/o binding motif and potential guanine-nucleotide exchange factor. Trends in Biochemical Sciences, 24(9), 340–341. https://doi.org/10.1016/s0968-0004(99)01441-3

Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits

Journal of Biological Chemistry / Dec 01, 2001

Wing, M. R., Houston, D., Kelley, G. G., Der, C. J., Siderovski, D. P., & Harden, T. K. (2001). Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits. Journal of Biological Chemistry, 276(51), 48257–48261. https://doi.org/10.1074/jbc.c100574200

Whither Goest the RGS Proteins?

Critical Reviews in Biochemistry and Molecular Biology / Jan 01, 1999

Siderovski, D. P., Strockbine, B., & Behe, C. I. (1999). Whither Goest the RGS Proteins? Critical Reviews in Biochemistry and Molecular Biology, 34(4), 215–251. https://doi.org/10.1080/10409239991209273

Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells

Journal of Biological Chemistry / Jul 01, 2002

Wang, Q., Liu, M., Mullah, B., Siderovski, D. P., & Neubig, R. R. (2002). Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells. Journal of Biological Chemistry, 277(28), 24949–24958. https://doi.org/10.1074/jbc.m203802200

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

Journal of Biological Chemistry / Jan 01, 2010

Nakamura, K., Kimple, A. J., Siderovski, D. P., & Johnson, G. L. (2010). PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation. Journal of Biological Chemistry, 285(3), 2077–2089. https://doi.org/10.1074/jbc.m109.065102

Molecular Cloning and Expression Analysis of RatRgs12andRgs14

Biochemical and Biophysical Research Communications / Apr 01, 1997

Snow, B. E., Antonio, L., Suggs, S., Gutstein, H. B., & Siderovski, D. P. (1997). Molecular Cloning and Expression Analysis of RatRgs12andRgs14. Biochemical and Biophysical Research Communications, 233(3), 770–777. https://doi.org/10.1006/bbrc.1997.6537

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

Journal of Biological Chemistry / Dec 01, 2001

Snyder, J. T., Rossman, K. L., Baumeister, M. A., Pruitt, W. M., Siderovski, D. P., Der, C. J., Lemmon, M. A., & Sondek, J. (2001). Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins. Journal of Biological Chemistry, 276(49), 45868–45875. https://doi.org/10.1074/jbc.m106731200

Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq

Journal of Biological Chemistry / Jun 01, 2001

Evanko, D. S., Thiyagarajan, M. M., Siderovski, D. P., & Wedegaertner, P. B. (2001). Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq. Journal of Biological Chemistry, 276(26), 23945–23953. https://doi.org/10.1074/jbc.m101154200

Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

Journal of Biological Chemistry / Jul 01, 2009

Kimple, A. J., Soundararajan, M., Hutsell, S. Q., Roos, A. K., Urban, D. J., Setola, V., Temple, B. R. S., Roth, B. L., Knapp, S., Willard, F. S., & Siderovski, D. P. (2009). Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2). Journal of Biological Chemistry, 284(29), 19402–19411. https://doi.org/10.1074/jbc.m109.024711

Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif

Biochemical Journal / Mar 15, 2004

KIMPLE, R. J., WILLARD, F. S., HAINS, M. D., JONES, M. B., NWEKE, G. K., & SIDEROVSKI, D. P. (2004). Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. Biochemical Journal, 378(3), 801–808. https://doi.org/10.1042/bj20031686

D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi‐specific GoLoco motif peptides

Journal of Neurochemistry / Feb 17, 2005

Webb, C. K., McCudden, C. R., Willard, F. S., Kimple, R. J., Siderovski, D. P., & Oxford, G. S. (2005). D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi‐specific GoLoco motif peptides. Journal of Neurochemistry, 92(6), 1408–1418. Portico. https://doi.org/10.1111/j.1471-4159.2004.02997.x

G protein signaling in the parasite Entamoeba histolytica

Experimental & Molecular Medicine / Mar 22, 2013

Bosch, D. E., & Siderovski, D. P. (2013). G protein signaling in the parasite Entamoeba histolytica. Experimental & Molecular Medicine, 45(3), e15–e15. https://doi.org/10.1038/emm.2013.30

Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13

Journal of Biological Chemistry / Dec 01, 2001

Blake, B. L., Wing, M. R., Zhou, J. Y., Lei, Q., Hillmann, J. R., Behe, C. I., Morris, R. A., Harden, T. K., Bayliss, D. A., Miller, R. J., & Siderovski, D. P. (2001). Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13. Journal of Biological Chemistry, 276(52), 49267–49274. https://doi.org/10.1074/jbc.m106565200

The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics / Sep 01, 2007

Kimple, A. J., Willard, F. S., Giguère, P. M., Johnston, C. A., Mocanu, V., & Siderovski, D. P. (2007). The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774(9), 1213–1220. https://doi.org/10.1016/j.bbapap.2007.06.002

Computational Design of the Sequence and Structure of a Protein-Binding Peptide

Journal of the American Chemical Society / Mar 09, 2011

Sammond, D. W., Bosch, D. E., Butterfoss, G. L., Purbeck, C., Machius, M., Siderovski, D. P., & Kuhlman, B. (2011). Computational Design of the Sequence and Structure of a Protein-Binding Peptide. Journal of the American Chemical Society, 133(12), 4190–4192. https://doi.org/10.1021/ja110296z

A direct fluorescence-based assay for RGS domain GTPase accelerating activity

Analytical Biochemistry / May 01, 2005

Willard, F. S., Kimple, A. J., Johnston, C. A., & Siderovski, D. P. (2005). A direct fluorescence-based assay for RGS domain GTPase accelerating activity. Analytical Biochemistry, 340(2), 341–351. https://doi.org/10.1016/j.ab.2005.02.015

A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding

Journal of Biological Chemistry / Dec 01, 2008

Willard, F. S., Zheng, Z., Guo, J., Digby, G. J., Kimple, A. J., Conley, J. M., Johnston, C. A., Bosch, D., Willard, M. D., Watts, V. J., Lambert, N. A., Ikeda, S. R., Du, Q., & Siderovski, D. P. (2008). A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding. Journal of Biological Chemistry, 283(52), 36698–36710. https://doi.org/10.1074/jbc.m804936200

Minimal Determinants for Binding Activated Gα from the Structure of a Gαi1−Peptide Dimer,

Biochemistry / Aug 30, 2006

Johnston, C. A., Lobanova, E. S., Shavkunov, A. S., Low, J., Ramer, J. K., Blaesius, R., Fredericks, Z., Willard, F. S., Kuhlman, B., Arshavsky, V. Y., & Siderovski, D. P. (2006). Minimal Determinants for Binding Activated Gα from the Structure of a Gαi1−Peptide Dimer,. Biochemistry, 45(38), 11390–11400. https://doi.org/10.1021/bi0613832

Covalent immobilization of histidine-tagged proteins for surface plasmon resonance

Analytical Biochemistry / Jun 01, 2006

Willard, F. S., & Siderovski, D. P. (2006). Covalent immobilization of histidine-tagged proteins for surface plasmon resonance. Analytical Biochemistry, 353(1), 147–149. https://doi.org/10.1016/j.ab.2006.02.004

Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia

Journal of Biological Chemistry / Dec 01, 2012

Cohen, S. P., Buckley, B. K., Kosloff, M., Garland, A. L., Bosch, D. E., Cheng, G., Radhakrishna, H., Brown, M. D., Willard, F. S., Arshavsky, V. Y., Tarran, R., Siderovski, D. P., & Kimple, A. J. (2012). Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia. Journal of Biological Chemistry, 287(50), 41706–41719. https://doi.org/10.1074/jbc.m112.423806

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Martin Tsui

San Francisco, California, United States of America
7 Years Experience
University of California, San Francisco
Education

Florida State University

Ph.D., Molecular Biophysics / July, 2017

Tallahassee, Florida, United States of America

University of California, San Diego

B.S., Chemistry / June, 2012

San Diego, California, United States of America
Experience

Stealth

Founder & CEO / January, 2023 — Present

Genome engineering

Amazon

Senior Scientist / December, 2021 — February, 2023

Molecular Diagnostics

Van Andel Institute

Postdoctoral Fellow / September, 2020 — April, 2021

Cryo-EM of membrane proteins

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (15)
Structural Biology
Cryo-EM
CRISPR
Molecular Assembly and Interaction
Molecular Biology
And 10 more
About
Martin Tsui is an accomplished scientist with a strong background in biochemistry. He received his Ph.D. in Molecular Biophysics from Florida State University in 2017, where he conducted research on the structure and function of CRISPR proteins. Prior to that, he obtained his B.S. in Chemistry from the University of California, San Diego in 2012. After completing his graduate studies, Martin founded his own company, Stealth, where he serves as a Founder & CEO. Under his leadership, the company has developed innovative solutions for the biotech industry and has gained recognition for its groundbreaking research. Before starting his company, Martin worked as a Senior Scientist at Amazon, where he applied his expertise in protein biochemistry and CRISPR to improve the company's product development processes and creating new products. He also gained valuable experience as a Postdoctoral Scholar at the University of California, San Francisco and Postdoctoral Fellow at the Van Andel Institute, where he studied cancer proteins, SARS-CoV-2, HIV proteins, and the role of proteins in neurodegenerative diseases, respectively. Martin is a highly driven and passionate individual who is dedicated to advancing the field of biotechnology. His impressive education and diverse experience have equipped him with the skills and knowledge to make significant contributions to the scientific community. He continues to pursue new opportunities to further his research and make a positive impact in the world of science.
Most Relevant Publications (1+)

16 total publications

Structure Principles of CRISPR-Cas Surveillance and Effector Complexes

Annual Review of Biophysics / Jun 22, 2015

Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939

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Boris Leibovitch

New York, New York, United States of America
30 Years Experience
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Education

Moscow Region State University

PhD, Molecular Biology / April, 1978

Moscow

Moscow Region State University

MS, Genetics / July, 1972

Moscow

Moscow Region State University

BS, Genetics / April, 1971

Moscow
Experience

NYU Langone Medical Center

Associate Research Scientist / June, 2021 — September, 2022

Wet lab research and teaching Molecular and Cell Biology in MD program

Icahn School of Medicine at Mount Sinai

Assistant Professor / July, 2004 — June, 2021

Wet lab research and teaching Molecular and Cell Biology in MD program

Washington University in St. Louis

Post-doctoral Research Associate / June, 1994 — June, 2004

Wet lab research and teaching Molecular and Cell Biology in MS program

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (8)
Cancer Research
Cell Biology
Developmental Biology
Molecular Biology
Hematology
And 3 more
About
I am experienced molecular and cell biologist with deep genetics background who worked many years in USA and Russia on the bench and as teacher. Both types of work had demanded extremely broad knowledge and understanding of developments in the fields. Participation in grant writing, editorial/reviewer work for scientific journals and consulting colleagues on these subjects added a lot to my broad experience as the scientist.
Most Relevant Publications (2+)

22 total publications

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Blood / Mar 15, 2008

Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122

Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster

Cold Spring Harbor Symposia on Quantitative Biology / Jan 01, 2004

HAYNES, K. A., LEIBOVITCH, B. A., RANGWALA, S. H., CRAIG, C., & ELGIN, S. C. R. (2004). Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia on Quantitative Biology, 69(0), 267–272. https://doi.org/10.1101/sqb.2004.69.267

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Dushani L. Palliyaguru, Ph.D.

Baltimore, MD, Maryland, United States of America
16 Years Experience
Toxicologist | Aging, Nutrition and Metabolism Research Scientist | Systems Biologist
Education

University of Pittsburgh

Ph.D., Environmental and Occupational Health (Toxicology) / May, 2016

Pittsburgh, Pennsylvania, United States of America

Clark University

B.A., Biochemistry and Molecular Biology, Mathematics / May, 2009

Worcester, Massachusetts, United States of America
Experience

National Institute on Aging Intramural Research Program, Translational Gerontology Branch

IRTA Postdoctoral Fellow, K99/R00 Grant Recipient / September, 2018 — Present

-Leading, managing and coordinating large population longitudinal studies within US Federal Government and Industry partnerships - Successfully writing, submitting, and managing grants and manuscripts to ensure continuity of research initiatives -Hiring, mentoring, and supervising research fellows and technicians -Applying epidemiological, machine learning and data science methods to multi-omics data to characterize biomarkers of aging and aging-related diseases -Testing nutritional and pharmacological compounds for lifespan extension, and prevention of chronic diseases (eg. Alzheimer’s)

University of Pittsburgh, Department of Pharmacology and Chemical Biology

Postdoctoral Fellow / May, 2016 — September, 2018

Identified a novel urinary biomarker of cruciferous vegetable intake in cancer prevention clinical trials using liquid chromatography mass spectrometry -Led and managed project that showed broccoli-derived sulforaphane prevented breast cancer through altering gene expression and lipidomics profiles

Healthcare Ready

Health Policy Fellow / January, 2017 — January, 2018

-Synthesized data, mined literature and wrote Toolkits/ Issue Brief on “Pharmacy and Emergency Preparedness: A Landscape Analysis”

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (16)
Nutrition
aging
Oncology
Hematology
Molecular Biology
And 11 more
About
·   Highly productive scientist with 13 years of multidisciplinary experience in toxicology, molecular nutrition, and aging/ disease biomarkers ·   Excellent communicator with proven record of advanced writing and presentation skills - manuscripts, conference presentations, and grants ·   Extensive experience in large study design, supervision and coordination, big data analysis, and management of junior scientists
Most Relevant Publications (1+)

20 total publications

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Free Radical Biology and Medicine / Dec 01, 2016

Palliyaguru, D. L., Chartoumpekis, D. V., Wakabayashi, N., Skoko, J. J., Yagishita, Y., Singh, S. V., & Kensler, T. W. (2016). Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms. Free Radical Biology and Medicine, 101, 116–128. https://doi.org/10.1016/j.freeradbiomed.2016.10.003

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Daniel Milej, Ph.D.

London, Ontario, Canada
15 Years Experience
Ph.D. in biomedical engineering
Education

Western University

Post-doctorate fellowship, Department of Medical Biophysics / June, 2019

London

Polish Academy of Science

PhD, Nalecz Institute of Biocybernetics and Biomedical Engineering / June, 2014

Warsaw

Military Univeristy of Technology

MSc, Department of Electronics / June, 2008

Warsaw
Experience

Lawson Research Institute

Research Associate / July, 2019 — July, 2025

Scientist / August, 2024 — Present

Western University

Postdoctoral fellow / September, 2014 — June, 2019

Assistant Professor / September, 2024 — Present

Polish Academy of Science

Researcher/PhD Student / June, 2008 — September, 2014

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (31)
Biomedical Optics
NIRS
fNIRS
Diffuse Correlation Spectroscopy
CBF
And 26 more
About
Dr. Daniel Milej is a multidisciplinary researcher with experience in medical biophysics, electronics, biocybernetics, biomedical optics and engineering. He is highly knowledgeable and experienced in a range of research techniques. He is a Scientist at the Lawson Research Institute, leading the transition of multimodal optical imaging systems from a research setting to clinical use in an ICU and OR environment, working closely with teams of nurses, surgeons, doctors and respiratory therapists. Previously, he was a Postdoctoral Fellow and Research Associate working on developing noninvasive modalities for brain activity monitoring in the Department of Medical Biophysics at Western University. Before that, Dr. Milej worked as a Researcher at the Nalecz Institute of Biocybernetics and Biomedical Engineering. He obtained his Ph.D. in 2014 from the Polish Academy of Science, specializing in Biocybernetics and Biomedical Engineering. He received his MSc in Electronics/Optoelectronics from the Military University of Technology, Warsaw, Poland, in 2008.
Most Relevant Publications (2+)

91 total publications

Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions

The FASEB Journal / May 01, 2022

Shoemaker, L., Suwalski, M., Milej, D., Shoemaker, J. K., Chui, J., & St. Lawrence, K. (2022). Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3459

Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain

Metabolites / Aug 31, 2022

Suwalski, M., Shoemaker, L. N., Shoemaker, J. K., Diop, M., Murkin, J. M., Chui, J., St. Lawrence, K., & Milej, D. (2022). Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain. Metabolites, 12(9), 817. https://doi.org/10.3390/metabo12090817

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Edward Elliott, Ph.D.

Portland, Oregon, United States of America
10 Years Experience
Ph.D. Chemist with expertise in nanoparticle synthesis and characterization, medical diagnostics, materials chemistry, additive manufacturing, and development of novel composites.
Education

University of Oregon

Ph.D., Chemistry, Nanoscience / May, 2014

Eugene, Oregon, United States of America
Experience

NanoVox

PreScouter

Voxtel, Inc.

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (15)
Nanoscale Characterization
Nanoparticle Synthesis
Surface Chemistry
Atomic and Molecular Physics, and Optics
Physical and Theoretical Chemistry
And 10 more
About
Ed has been working in the field of nanoscience and chemistry since completing his Ph.D. in 2014. He has worked on a variety of projects ranging from drug delivery to nanodevice fabrication and characterization. Elliott has published numerous papers in both peer-reviewed journals and conferences and holds several US patents. He has also presented his research at various international conferences and workshops and currently works as a consultant focused on sustainability and green chemistry.

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Burcu Vitrinel, Ph.D.

San Francisco
11 Years Experience
Cross-functional life sciences strategy professional with a Ph.D. in genetics
Education

New York University

Ph.D., Developmental Genetics / May, 2021

New York, New York, United States of America

M.Sc., Molecular Medicine / September, 2015

Berlin

Sabancı University

B.Sc., Bioengineering / May, 2013

Istanbul
Experience

Putnam Associates

Life Sciences Consultant / July, 2021 — November, 2023

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (15)
Molecular Biology
Cell Biology
Aging
Computer Science Applications
Virology
And 10 more
About
Cross-functional life sciences **strategy** professional with a doctoral degree in **genetics**; worked on 16+ projects in collaboration with 7+ big pharma clients as the lead consultant in a **client-facing** role. Exceptional understanding of current life sciences **market trends**. Scientist with 10+ years of wet-lab with hands-on **CRISPR-Cas9 gene** **editing and tandem mass-spectrometry** experience with 3 first-author papers. Experienced primary market researcher for pharmaceutical companies. Award-winning science communicator for a wide range of audiences tailored to different internal and external stakeholders.
Most Relevant Publications (1+)

10 total publications

Exploiting Interdata Relationships in Next-generation Proteomics Analysis

Molecular & Cellular Proteomics / Aug 01, 2019

Vitrinel, B., Koh, H. W. L., Mujgan Kar, F., Maity, S., Rendleman, J., Choi, H., & Vogel, C. (2019). Exploiting Interdata Relationships in Next-generation Proteomics Analysis. Molecular & Cellular Proteomics, 18(8), S5–S14. https://doi.org/10.1074/mcp.mr118.001246

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Elvira Forte

New York, New York, United States of America
15 Years Experience
Scientific strategist • Senior Scientist • Senior Scientific Editor
Education

Sapienza University of Rome

PhD, Pasteurian Sciences / January, 2011

Rome

Sapienza University of Rome

Master, Medical, Molecular and Cellular Biotechnology / October, 2006

Rome

Sapienza University of Rome

Bachelor, Biotechnology / October, 2004

Rome
Experience

Springer Nature

Associate/Senior Editor / June, 2021 — February, 2024

Helped shape and launch a new journal, Nature Cardiovascular Research, which publishes exceptional advances in the fields of cardiac, vascular, and blood biology, covering fundamental, translational, clinical, and public health research. • Assessed the novelty and impact of manuscripts within all the topics covered by the journal and chaperoned the whole revision process until acceptance for over 40% of all the content published by the journal since its start, with optimal processing times and excellent feedback from the authors. • Interfaced with scientists around the World, provided scientific guidance on how to improve manuscripts, or recommended more appropriate journals to publish with. Commissioned Comments, Reviews, News and Views on current topics, and summarized novel scientific findings in meaningful snippets and Research Highlights. • Contributed to the training and supervision of 2 Associate Editors; covered the Chief Editor's functions when needed.

Research Fellow/Associate Research Scientist / January, 2017 — June, 2021

• Analyzed the dynamic cellular changes during the fibrotic repair post-myocardial infarction, using cutting-edge techniques such as single-cell RNAseq with 10xChromium. Learned how to perform myocardial infarction in mice and assess the cardiac function via echography; analyze scRNAseq data using the Seurat package on R studio. • Completed a project aimed to characterize similarities and differences among fibroblasts from different organs cultured in the same conditions. Through cytometric, transcriptomic analysis, functional assays, shRNA and CRISPR-Cas9-mediated in vitro gene knockdowns we showed that fibroblasts isolated from different organs retain the expression of key transcription factors reflecting their embryological origin. • Collaborated with other laboratories in the Institute to design new mice models that could possibly recapitulate the symptoms of COVID-19; to analyze the response of mice with diverse genetic backgrounds to stressors.

Post-doctoral fellow/ Co-joint lecturer / May, 2013 — November, 2016

Developed projects aimed at understanding the embryological origin and function of a population of putative progenitor cells, cardiac colony forming unit fibroblasts cCFU-F, identified 2 years before in the lab (PMID: 22136928). • Performed cell lineage tracing and designed in vitro and in vivo cellular assays to assess the functional and immunomodulatory properties of PDGFRa+ fibroblasts in homeostasis and post-myocardial infarction with or without treatment with the PDGF-AB ligands. The data, presented in 3 international conferences and included in a preprint manuscript, have supported the use of a short-term treatment with PDGF-AB in a preclinical model of acute myocardial infarction in pigs. • Co-supervised 2 Ph.D. students at University of New South Wales

Scientific Editor / March, 2024 — Present

Consultant freelancer position within a team of former journal editors and grants specialists • Helped scientists increase the impact of their science by providing advice, in-depth editing, and feedback on manuscripts.

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (26)
fibrosis
inflammation
cardiomyopathies
Physiology
Cardiology and Cardiovascular Medicine
And 21 more
About
Motivated and growth-driven biomedical scientist with over 15 years of experience in the cardiovascular field. Strong background in cell and molecular biology, data analysis, and interpretation. Seeking #newopportunities to deliver value as a Senior Scientist, Associate Principal Scientist, Scientific Liaison, or Scientific Consultant within a company that combines new technologies such as single-cell omics and AI for drug discovery and personalized medicine. <br> Throughout my career, I've used various in vivo and in vitro models to investigate the molecular and cellular mechanisms of fibrosis and inflammation in the heart, and how these mechanisms are affected in mice with different genetic backgrounds. My experience includes project management and mentoring. I completed three projects involving international collaborations, supervised two junior researchers, and taught cellular and molecular techniques to at least six professionals. As one of the launching editors and senior editor at Nature Cardiovascular Research, I oversaw the quality of the content published in the journal and the editorial process. I collaborated with authors, reviewers, and editors to ensure the highest standards of scientific rigor, relevance, and innovation. I also contributed to the journal's vision, strategy, and outreach, promoting the latest advances and discoveries in the cardiovascular and hematology fields. This experience has sharpened my analytical and communication skills and broadened my understanding of the field, covering a wide range of studies, from basic research to clinical, epidemiological, and public health research. My mission is to advance the knowledge and practice of cardiovascular medicine and to bridge the gap between research and clinical applications. Keywords: cardiovascular, #fibrosis, inflammation, cardioimmunology, RNA, single-cell biology, #transcriptomics, imaging, animal models, small animal surgery, and scientific writing.
Most Relevant Publications (1+)

63 total publications

Biochemistry and biology: Heart-to-heart to investigate cardiac progenitor cells

Biochimica et Biophysica Acta (BBA) - General Subjects / Feb 01, 2013

Chimenti, I., Forte, E., Angelini, F., Messina, E., & Giacomello, A. (2013). Biochemistry and biology: Heart-to-heart to investigate cardiac progenitor cells. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830(2), 2459–2469. https://doi.org/10.1016/j.bbagen.2012.08.004

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Shariq Usmani, PhD

Boston, Massachusetts, United States of America
15 Years Experience
Massachusetts General Hospital, Harvard Medical School
Education

University of Konstanz

PhD, Molecular and Cell Biology / May, 2011

Konstanz

Harvard University

Postdoctoral fellow, Virology/Immunology / 2019

Cambridge, Massachusetts, United States of America
Experience

Cabaletta Bio

Scientific Director / 2024 — Present

I lead a research team in the preclinical R&D organization at Cabaletta bio. I directly manage a talented group of Senior Scientists, Scientists and Research Associates to spearhead and drive innovation in cell therapies and biologics in autoimmune disease indications.

Sana Biotechnology

Principal Scientist / 2022 — 2023

As a team lead, I led efforts to establish in vivo genome editing platform, vector design/engineering and optimization, with a broader goal to develop innovative and effective genomic medicine for unmet medical needs.

Zohdan Bio

Consultant / 2024 — Present

Providing strategic support for all aspects of preclinical, R&D programs in gene therapy, genome editing and virology and immunology space.

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (9)
Microbiology
Virology
Immunology
Molecular Biology
Genetics
And 4 more
About
Dr. Shariq Usmani is scientific director at Cabaletta bio, a leader in cell therapy for autoimmune diseases (https://www.cabalettabio.com). He leads a research team in preclinical R&D organization at Cabaletta bio. He directly manage a talented group of Senior Scientists, Scientists and Research Associates to spearhead and drive innovation in cell therapies and biologics in autoimmune disease indications. <br> He is also serves as consultant at Zohdan Bio, where he provides strategic support for preclinical R&D programs focused on gene therapy, genome editing, and virology. With a deep foundation in oncology and biologics, Dr. Usmani has led groundbreaking work in both academia and industry, including his tenures at Sana Biotechnology, Harvard Medical School and Massachusetts General Hospital. He's led and spearheaded the development of innovative in vivo genome editing platforms, optimized viral vectors, and engineered cutting-edge reporter assays.
Most Relevant Publications (1+)

22 total publications

Atomic force microscopy of microvillous cell surface dynamics at fixed and living alveolar type II cells

Analytical and Bioanalytical Chemistry / Nov 30, 2010

Hecht, E., Usmani, S. M., Albrecht, S., Wittekindt, O. H., Dietl, P., Mizaikoff, B., & Kranz, C. (2010). Atomic force microscopy of microvillous cell surface dynamics at fixed and living alveolar type II cells. Analytical and Bioanalytical Chemistry, 399(7), 2369–2378. https://doi.org/10.1007/s00216-010-4407-z

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David Proctor

Midland, Michigan, United States of America
27 Years Experience
PhD biochemist with expertise in higher education, applied microbiology R&D, and science policy
Education

Pennsylvania State University

PhD, Chemistry / August, 2004

University Park, Pennsylvania, United States of America

Commonwealth University-Lock Haven

BS, Biology, Chemistry / May, 1998

Lock Haven
Experience

Mid Michigan College

Adjunct Faculty / 2017 — Present

Saginaw Valley State University

Adjunct Faculty / August, 2015 — August, 2020

CSRA Inc

Scientific Review Officer / 2015 — 2018

Most Relevant Research Expertise
Biochemistry
Other Research Expertise (3)
Structural biology
Biophysics
Microbiology
About
David Proctor is the Technical Director at the International Antimicrobial Council (IAC) and Adjunct Faculty in Chemistry and Biology at Mid Michigan College. As Technical Director at the International Antimicrobial Council, David promotes the responsible use of microbial and odor control technologies through research, education, and community building. His research interests include the development of test methods for multi-functional finishes and the impact of microbial and odor control finishes on the establishment of circular economies for textiles and other sectors. Previously, David was Adjunct Faculty at Saginaw Valley State University. He was also a Scientific Review Officer with CSRA Inc. David served as a AAAS Science & Technology Policy Fellow in the Office of Advanced Cyberinfrastructure at the National Science Foundation and was a Research Associate and a Christine Mirzayan Science and Technology Policy Graduate Fellow with the Committee on Science, Engineering, Medicine, and Public Policy at the National Academies of Sciences, Engineering and Medicine. David was a postdoctoral researcher in structural biology at the University of Dundee, where he helped to establish the UK Research Staff Association to provide a collective voice for UK researchers. He completed a doctorate in chemistry at the Pennsylvania State University.

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Example Biochemistry projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Biochemistry?

Drug Discovery and Development

A pharmaceutical company can collaborate with a Biochemistry expert to identify and validate drug targets, design and optimize drug molecules, and evaluate their efficacy and safety. This collaboration can accelerate the drug discovery and development process, leading to the creation of new and effective treatments for various diseases.

Biotechnology Advancements

Biochemistry researchers can contribute to the development of biotechnological products and processes. They can optimize enzyme reactions, engineer proteins with desired properties, and improve the efficiency of biofuel production. By collaborating with these experts, companies can enhance their biotechnology capabilities and create innovative solutions for a wide range of applications.

Crop Improvement and Agriculture

Companies in the agriculture industry can benefit from collaborating with Biochemistry experts to improve crop yield, quality, and resistance to pests and diseases. These researchers can study the biochemical pathways involved in plant growth and development, identify key genes and proteins, and develop strategies for genetic engineering and crop improvement. This collaboration can lead to the development of more productive and sustainable agricultural practices.

Food Science and Nutrition

Biochemistry experts can contribute to the development of healthier and more nutritious food products. They can study the biochemical composition of food, analyze nutritional content, and develop methods for food fortification and preservation. By collaborating with these researchers, companies can create innovative food products that meet consumer demands for health, sustainability, and taste.

Environmental Remediation

Biochemistry researchers can play a crucial role in addressing environmental challenges. They can study the biochemical processes involved in pollutant degradation, develop bioremediation strategies, and optimize the use of microorganisms for environmental cleanup. By collaborating with these experts, companies can develop sustainable solutions for pollution control and environmental remediation.