Work with thought leaders and academic experts in biochemistry

Companies can greatly benefit from working with experts in the field of Biochemistry. These researchers bring a deep understanding of molecular processes, biochemical reactions, and the structure and function of biomolecules. They can provide valuable insights and solutions for various industries, including pharmaceuticals, biotechnology, agriculture, food science, and environmental science. By collaborating with Biochemistry experts, companies can enhance their research and development efforts, accelerate innovation, improve product quality, optimize production processes, and address complex challenges. Their expertise can also contribute to the discovery of new drugs, the development of sustainable technologies, and the improvement of health and well-being.

Experts on NotedSource with backgrounds in biochemistry include Boris Leibovitch, Sheed Itaman, Michael W Harman, Keiran Thompson, Daniel Milej, Ph.D., Aimee Eggler, Dushani L. Palliyaguru, Ph.D., Elle Wang, Michael Hickner, Jeffrey Townsend, Tim Osswald, Ammon Posey, Keisha Walters, and Edoardo Airoldi.

Boris Leibovitch

New York, New York, United States of America
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Most Relevant Research Interests
Biochemistry
Other Research Interests (11)
Cancer Research
Cell Biology
Developmental Biology
Molecular Biology
Multidisciplinary
And 6 more
About
I am experienced molecular and cell biologist with deep genetics background who worked many years in USA and Russia on the bench and as teacher. Both types of work had demanded extremely broad knowledge and understanding of developments in the fields. Participation in grant writing, editorial/reviewer work for scientific journals and consulting colleagues on these subjects added a lot to my broad experience as the scientist.
Most Relevant Publications (2+)

22 total publications

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Blood / Mar 15, 2008

Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122

Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster

Cold Spring Harbor Symposia on Quantitative Biology / Jan 01, 2004

HAYNES, K. A., LEIBOVITCH, B. A., RANGWALA, S. H., CRAIG, C., & ELGIN, S. C. R. (2004). Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia on Quantitative Biology, 69(0), 267–272. https://doi.org/10.1101/sqb.2004.69.267

Michael W Harman

East Greenwich, RI, Rhode Island, United States of America
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Interests
Biochemistry
Other Research Interests (15)
Bacteria & Cell Bio-Physics
Biomechanics
Infectious Diseases
Immunology
Microbiology
And 10 more
About
Highly skilled, energetic, and motivated professional empowered by over a decade of cross-disciplinary engineering and scientific applications experience. Presenting elegant solutions to prevalent biomedical challenges. Motivated by driving deliverable outcomes from complex research studies through effective leadership, active consulting work, and innovative problem-solving techniques. Seeking to make an immediate impact in a fast-paced biotechnology environment capitalizing on my advanced comprehension, continued professional growth, strategic product development expertise, and active network of personal connections across all areas of science, engineering, medicine, manufacturing and healthcare.
Most Relevant Publications (2+)

15 total publications

Measuring DNA content in live cells by fluorescence microscopy

Cell Division / Sep 04, 2018

Gomes, C. J., Harman, M. W., Centuori, S. M., Wolgemuth, C. W., & Martinez, J. D. (2018). Measuring DNA content in live cells by fluorescence microscopy. Cell Division, 13(1). https://doi.org/10.1186/s13008-018-0039-z

Vinculin in Neutrophil Adhesion, Motility and Trafficking

The FASEB Journal / Apr 01, 2018

Wilson, Z., Harman, M., Hazlett, L., Odzer, J., Witt, H., Franck, C., Reichner, J., & Lefort, C. (2018). Vinculin in Neutrophil Adhesion, Motility and Trafficking. The FASEB Journal, 32(S1). Portico. https://doi.org/10.1096/fasebj.2018.32.1_supplement.280.11

Daniel Milej, Ph.D.

London, Ontario, Canada
Ph.D. in biomedical engineering
Most Relevant Research Interests
Biochemistry
Other Research Interests (37)
Biomedical Optics
NIRS
fNIRS
Diffuse Correlation Spectroscopy
CBF
And 32 more
About
Dr. Daniel Milej is a multidisciplinary researcher with experience in medical biophysics, electronics, biocybernetics, biomedical optics and engineering. He is highly knowledgeable and experienced in a range of research techniques. He is currently a Research Associate at the Lawson Health Research Institute, leading the transition of multimodal optical imaging systems from a research setting to clinical use in an ICU and OR environment, working closely with teams of nurses, surgeons, doctors and respiratory therapists. Previously he was a postdoctoral fellow working on developing noninvasive modalities for brain activity monitoring in the Department of Medical Biophysics at Western University. Before that, Dr. Milej worked as a researcher at the Nalecz Institute of Biocybernetics and Biomedical Engineering. He obtained his Ph.D. in 2014 from the Polish Academy of Science, specializing in Electronics and Biomedical Engineering. He received his MSc from the Military University of Technology in 2008.
Most Relevant Publications (2+)

91 total publications

Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions

The FASEB Journal / May 01, 2022

Shoemaker, L., Suwalski, M., Milej, D., Shoemaker, J. K., Chui, J., & St. Lawrence, K. (2022). Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3459

Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain

Metabolites / Aug 31, 2022

Suwalski, M., Shoemaker, L. N., Shoemaker, J. K., Diop, M., Murkin, J. M., Chui, J., St. Lawrence, K., & Milej, D. (2022). Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain. Metabolites, 12(9), 817. https://doi.org/10.3390/metabo12090817

Aimee Eggler

Villanova, Pennsylvania, United States of America
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Interests
Biochemistry
Other Research Interests (26)
Biochemistry education
Cell culture
Oxidative stress
Natural products
Disease prevention
And 21 more
About
Dr. Eggler has 20 years of experience in the field of redox biology, with a focus on the Nrf2 transcription factor, a master regulator of antioxidant, detoxification and anti-inflammatory genes. She is also an award-winning educator and the recipient of the Villanova University Junior Faculty Excellence in Teaching award. Her interests in education include innovation in teaching metabolism from a logic-based perspective.
Most Relevant Publications (10+)

25 total publications

Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

Free Radical Biology and Medicine / Jun 01, 2021

Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, L. F., & Davies, M. J. (2021). Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols. Free Radical Biology and Medicine, 169, 1–11. https://doi.org/10.1016/j.freeradbiomed.2021.03.040

Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation

Free Radical Biology and Medicine / Aug 01, 2018

Bauman, B. M., Jeong, C., Savage, M., Briker, A. L., Janigian, N. G., Nguyen, L. L., Kemmerer, Z. A., & Eggler, A. L. (2018). Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane’s antioxidant response element activation, even as they suppress Nrf2 protein accumulation. Free Radical Biology and Medicine, 124, 532–540. https://doi.org/10.1016/j.freeradbiomed.2018.06.039

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013

Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112

Screening for natural chemoprevention agents that modify human Keap1

Analytical Biochemistry / Feb 01, 2012

Hu, C., Nikolic, D., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2012). Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry, 421(1), 108–114. https://doi.org/10.1016/j.ab.2011.10.028

Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1

Biochemical and Biophysical Research Communications / Oct 01, 2010

Small, E., Eggler, A., & Mesecar, A. D. (2010). Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1. Biochemical and Biophysical Research Communications, 400(4), 471–475. https://doi.org/10.1016/j.bbrc.2010.08.062

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1

Biochemical Journal / Jul 29, 2009

Eggler, A. L., Small, E., Hannink, M., & Mesecar, A. D. (2009). Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. Biochemical Journal, 422(1), 171–180. https://doi.org/10.1042/bj20090471

The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides

Archives of Biochemistry and Biophysics / Nov 01, 2008

McAdams, K., Casper, E. S., Matthew Haas, R., Santarsiero, B. D., Eggler, A. L., Mesecar, A., & Halkides, C. J. (2008). The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides. Archives of Biochemistry and Biophysics, 479(2), 105–113. https://doi.org/10.1016/j.abb.2008.08.019

The C Terminus of the Escherichia coli RecA Protein Modulates the DNA Binding Competition with Single-stranded DNA-binding Protein

Journal of Biological Chemistry / May 01, 2003

Eggler, A. L., Lusetti, S. L., & Cox, M. M. (2003). The C Terminus of the Escherichia coli RecA Protein Modulates the DNA Binding Competition with Single-stranded DNA-binding Protein. Journal of Biological Chemistry, 278(18), 16389–16396. https://doi.org/10.1074/jbc.m212920200

The Rad51-dependent Pairing of Long DNA Substrates Is Stabilized by Replication Protein A

Journal of Biological Chemistry / Oct 01, 2002

Eggler, A. L., Inman, R. B., & Cox, M. M. (2002). The Rad51-dependent Pairing of Long DNA Substrates Is Stabilized by Replication Protein A. Journal of Biological Chemistry, 277(42), 39280–39288. https://doi.org/10.1074/jbc.m204328200

DNA Pairing and Strand Exchange by the Escherichia coli RecA and Yeast Rad51 Proteins without ATP Hydrolysis

Journal of Biological Chemistry / Oct 01, 2001

Rice, K. P., Eggler, A. L., Sung, P., & Cox, M. M. (2001). DNA Pairing and Strand Exchange by the Escherichia coli RecA and Yeast Rad51 Proteins without ATP Hydrolysis. Journal of Biological Chemistry, 276(42), 38570–38581. https://doi.org/10.1074/jbc.m105678200

Elle Wang

San Francisco, California, United States of America
Lead Research Scientist at National AI Institute for Adult Learning and Online Education
Most Relevant Research Interests
Biochemistry
Other Research Interests (14)
Educational Technology
AI in Higher Ed
Online learning
Intelligent technologies
Learning Analytics
And 9 more
About
Ellen (Elle) Wang is a cognitive scientist with a focus on educational applications of artificial intelligence (AI). She is currently a lead research scientist at the National AI Institute for Adult Learning and Online Education and a staff research scientist at the Action Lab at Arizona State University. Wang received her PhD in Cognitive Science in Education from Columbia University in 2017. Her research focuses on how AI can be used to support and improve learning outcomes, with a particular focus on online and adult learners. She has developed and evaluated AI-based programs and systems for a variety of applications, including tutoring, intelligent course recommendation, and assessment. Wang’s work has been published in a variety of prestigious journals, including the Journal of Educational Psychology, the British Journal of Educational Technology, and the Journal of Experimental Psychology: Applied. She has also presented her work at numerous international conferences, including the Association for the Advancement of Artificial Intelligence (AAAI) and the International Conference on Intelligent Tutoring Systems (ITS).
Most Relevant Publications (1+)

26 total publications

Commentary: Massive open online courses

Biochemistry and Molecular Biology Education / Jul 01, 2013

Parslow, G. R. (2013). Commentary: Massive open online courses. Biochemistry and Molecular Biology Education, 41(4), 278–279. https://doi.org/10.1002/bmb.20710

Michael Hickner

Michigan State University
Most Relevant Research Interests
Biochemistry
Other Research Interests (43)
polymers : 3D printing : materials chemistry : energy : water
Colloid and Surface Chemistry
General Chemistry
Catalysis
Pollution
And 38 more
About
Michael Hickner is an accomplished researcher and educator with an extensive background in chemical engineering. He received his PhD in Chemical Engineering from Virginia Tech in 2003. For the past 15 years, Hickner has been a Rogerson Endowed Professor at Michigan State University, where he has conducted highly acclaimed research in the areas of sustainable energy technologies and nanomanufacturing. Previous to this appointment, Hickner was a Senior Member of the Technical Staff at Sandia National Laboratories, where he conducted post-doctoral research in the fields of materials science, nanotechnology, and catalysis. Given his diverse skill set and supportive leadership style, Michigan State students look to Hickner to provide them with the guidance, mentorship, and educational tools necessary to excel in the field of chemical engineering.
Most Relevant Publications (20+)

217 total publications

Highly Stable, Anion Conductive, Comb-Shaped Copolymers for Alkaline Fuel Cells

Journal of the American Chemical Society / Jun 27, 2013

Li, N., Leng, Y., Hickner, M. A., & Wang, C.-Y. (2013). Highly Stable, Anion Conductive, Comb-Shaped Copolymers for Alkaline Fuel Cells. Journal of the American Chemical Society, 135(27), 10124–10133. https://doi.org/10.1021/ja403671u

Fabrication and characterization of heteropolyacid (H3PW12O40)/directly polymerized sulfonated poly(arylene ether sulfone) copolymer composite membranes for higher temperature fuel cell applications

Journal of Membrane Science / Feb 01, 2003

Kim, Y. S., Wang, F., Hickner, M., Zawodzinski, T. A., & McGrath, J. E. (2003). Fabrication and characterization of heteropolyacid (H3PW12O40)/directly polymerized sulfonated poly(arylene ether sulfone) copolymer composite membranes for higher temperature fuel cell applications. Journal of Membrane Science, 212(1–2), 263–282. https://doi.org/10.1016/s0376-7388(02)00507-0

Solid-State Water Electrolysis with an Alkaline Membrane

Journal of the American Chemical Society / May 24, 2012

Leng, Y., Chen, G., Mendoza, A. J., Tighe, T. B., Hickner, M. A., & Wang, C.-Y. (2012). Solid-State Water Electrolysis with an Alkaline Membrane. Journal of the American Chemical Society, 134(22), 9054–9057. https://doi.org/10.1021/ja302439z

Improved ATR-FTIR detection of hydrocarbons in water with semi-crystalline polyolefin coatings on ATR elements

The Analyst / Jan 01, 2018

Nam, C., Zimudzi, T. J., Wiencek, R. A., Chung, T. C. M., & Hickner, M. A. (2018). Improved ATR-FTIR detection of hydrocarbons in water with semi-crystalline polyolefin coatings on ATR elements. The Analyst, 143(22), 5589–5596. https://doi.org/10.1039/c8an01280f

Anion exchange membranes by bromination of tetramethylbiphenol-based poly(sulfone)s

Polymer Chemistry / Jan 01, 2017

Yan, J., Zhu, L., Chaloux, B. L., & Hickner, M. A. (2017). Anion exchange membranes by bromination of tetramethylbiphenol-based poly(sulfone)s. Polymer Chemistry, 8(16), 2442–2449. https://doi.org/10.1039/c7py00026j

Bicarbonate and chloride anion transport in anion exchange membranes

Journal of Membrane Science / Sep 01, 2016

Amel, A., Gavish, N., Zhu, L., Dekel, D. R., Hickner, M. A., & Ein-Eli, Y. (2016). Bicarbonate and chloride anion transport in anion exchange membranes. Journal of Membrane Science, 514, 125–134. https://doi.org/10.1016/j.memsci.2016.04.027

Crosslinking of comb-shaped polymer anion exchange membranes via thiol–ene click chemistry

Polymer Chemistry / Jan 01, 2016

Zhu, L., Zimudzi, T. J., Li, N., Pan, J., Lin, B., & Hickner, M. A. (2016). Crosslinking of comb-shaped polymer anion exchange membranes via thiol–ene click chemistry. Polymer Chemistry, 7(14), 2464–2475. https://doi.org/10.1039/c5py01911g

Correction: Crosslinking of comb-shaped polymer anion exchange membranes via thiol–ene click chemistry

Polymer Chemistry / Jan 01, 2016

Zhu, L., Zimudzi, T. J., Li, N., Pan, J., Lin, B., & Hickner, M. A. (2016). Correction: Crosslinking of comb-shaped polymer anion exchange membranes via thiol–ene click chemistry. Polymer Chemistry, 7(14), 2589–2589. https://doi.org/10.1039/c6py90044e

Imidazolium-based organic–inorganic hybrid anion exchange membranes for fuel cell applications

Journal of Membrane Science / Jun 01, 2016

Feng, T., Lin, B., Zhang, S., Yuan, N., Chu, F., Hickner, M. A., Wang, C., Zhu, L., & Ding, J. (2016). Imidazolium-based organic–inorganic hybrid anion exchange membranes for fuel cell applications. Journal of Membrane Science, 508, 7–14. https://doi.org/10.1016/j.memsci.2016.02.019

Specific ion effects on the permselectivity of sulfonated poly(ether sulfone) cation exchange membranes

Journal of Membrane Science / Jun 01, 2016

Cassady, H. J., Cimino, E. C., Kumar, M., & Hickner, M. A. (2016). Specific ion effects on the permselectivity of sulfonated poly(ether sulfone) cation exchange membranes. Journal of Membrane Science, 508, 146–152. https://doi.org/10.1016/j.memsci.2016.02.048

Low-temperature crosslinking of anion exchange membranes

Polymer Chemistry / Jan 01, 2014

Wang, L., & Hickner, M. A. (2014). Low-temperature crosslinking of anion exchange membranes. Polymer Chemistry, 5(8), 2928–2935. https://doi.org/10.1039/c3py01490h

Layered zirconium phosphate sulfophenylphosphonates reinforced sulfonated poly (fluorenyl ether ketone) hybrid membranes with high proton conductivity and low vanadium ion permeability

Journal of Membrane Science / Sep 01, 2013

Pan, J., Wang, S., Xiao, M., Hickner, M., & Meng, Y. (2013). Layered zirconium phosphate sulfophenylphosphonates reinforced sulfonated poly (fluorenyl ether ketone) hybrid membranes with high proton conductivity and low vanadium ion permeability. Journal of Membrane Science, 443, 19–27. https://doi.org/10.1016/j.memsci.2013.04.068

Optimizing membrane thickness for vanadium redox flow batteries

Journal of Membrane Science / Jun 01, 2013

Chen, D., Hickner, M. A., Agar, E., & Kumbur, E. C. (2013). Optimizing membrane thickness for vanadium redox flow batteries. Journal of Membrane Science, 437, 108–113. https://doi.org/10.1016/j.memsci.2013.02.007

Polymer electrolyte membranes based on poly(arylene ether sulfone) with pendant perfluorosulfonic acid

Polym. Chem. / Jan 01, 2013

Chang, Y., Brunello, G. F., Fuller, J., Disabb-Miller, M. L., Hawley, M. E., Kim, Y. S., Hickner, M. A., Jang, S. S., & Bae, C. (2013). Polymer electrolyte membranes based on poly(arylene ether sulfone) with pendant perfluorosulfonic acid. Polym. Chem., 4(2), 272–281. https://doi.org/10.1039/c2py20666h

Directly fluorinated polyaromatic composite membranes for vanadium redox flow batteries

Journal of Membrane Science / Oct 01, 2012

Chen, D., Hickner, M. A., Wang, S., Pan, J., Xiao, M., & Meng, Y. (2012). Directly fluorinated polyaromatic composite membranes for vanadium redox flow batteries. Journal of Membrane Science, 415–416, 139–144. https://doi.org/10.1016/j.memsci.2012.04.048

Metal-Cation-Based Anion Exchange Membranes

Journal of the American Chemical Society / Mar 02, 2012

Zha, Y., Disabb-Miller, M. L., Johnson, Z. D., Hickner, M. A., & Tew, G. N. (2012). Metal-Cation-Based Anion Exchange Membranes. Journal of the American Chemical Society, 134(10), 4493–4496. https://doi.org/10.1021/ja211365r

Single-Crystal Colloidal Nanosheets of GeS and GeSe

Journal of the American Chemical Society / Oct 13, 2010

Vaughn, D. D., Patel, R. J., Hickner, M. A., & Schaak, R. E. (2010). Single-Crystal Colloidal Nanosheets of GeS and GeSe. Journal of the American Chemical Society, 132(43), 15170–15172. https://doi.org/10.1021/ja107520b

An NMR study of methanol diffusion in polymer electrolyte fuel cell membranes

Journal of Membrane Science / Mar 15, 2005

EVERY, H., HICKNER, M., MCGRATH, J., & ZAWODZINSKIJR, T. (2005). An NMR study of methanol diffusion in polymer electrolyte fuel cell membranes. Journal of Membrane Science, 250(1–2), 183–188. https://doi.org/10.1016/j.memsci.2004.10.026

Sulfonated poly(arylene ether sulfone) copolymer proton exchange membranes: composition and morphology effects on the methanol permeability

Journal of Membrane Science / Nov 01, 2004

Kim, Y. S., Hickner, M. A., Dong, L., Pivovar, B. S., & McGrath, J. E. (2004). Sulfonated poly(arylene ether sulfone) copolymer proton exchange membranes: composition and morphology effects on the methanol permeability. Journal of Membrane Science, 243(1–2), 317–326. https://doi.org/10.1016/j.memsci.2004.06.035

Direct polymerization of sulfonated poly(arylene ether sulfone) random (statistical) copolymers: candidates for new proton exchange membranes

Journal of Membrane Science / Mar 01, 2002

Wang, F., Hickner, M., Kim, Y. S., Zawodzinski, T. A., & McGrath, J. E. (2002). Direct polymerization of sulfonated poly(arylene ether sulfone) random (statistical) copolymers: candidates for new proton exchange membranes. Journal of Membrane Science, 197(1–2), 231–242. https://doi.org/10.1016/s0376-7388(01)00620-2

Jeffrey Townsend

New Haven, CT
Professor of Biostatistics and Ecology & Evolutionary Biology
Most Relevant Research Interests
Biochemistry
Other Research Interests (71)
Statistics
cancer genetics
disease modeling
antibiotic resistance
Evolutionary Genomics
And 66 more
About
Jeffrey Townsend is a Professor of Organismic and Evolutionary Biology at Yale University. He received his Ph.D. from Harvard University in 2002 and his Sc.B. from Brown University in 1994. He has been a teacher at St. Ann's School and an Assistant Professor at the University of Connecticut. He is currently the Elihu Professor of Biostatistics at Yale University.
Most Relevant Publications (7+)

207 total publications

Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa

mSystems / Jun 28, 2022

Wang, Z., Lopez-Giraldez, F., Slot, J., Yarden, O., Trail, F., & Townsend, J. P. (2022). Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa. MSystems, 7(3). https://doi.org/10.1128/msystems.00232-22

PathScore: a web tool for identifying altered pathways in cancer data

Bioinformatics / Aug 08, 2016

Gaffney, S. G., & Townsend, J. P. (2016). PathScore: a web tool for identifying altered pathways in cancer data. Bioinformatics, 32(23), 3688–3690. https://doi.org/10.1093/bioinformatics/btw512

Epidemiological mechanisms of genetic resistance to kuru

Journal of The Royal Society Interface / Aug 06, 2013

Atkins, K. E., Townsend, J. P., Medlock, J., & Galvani, A. P. (2013). Epidemiological mechanisms of genetic resistance to kuru. Journal of The Royal Society Interface, 10(85), 20130331. https://doi.org/10.1098/rsif.2013.0331

AuthorReward: increasing community curation in biological knowledge wikis through automated authorship quantification

Bioinformatics / Jun 03, 2013

Dai, L., Tian, M., Wu, J., Xiao, J., Wang, X., Townsend, J. P., & Zhang, Z. (2013). AuthorReward: increasing community curation in biological knowledge wikis through automated authorship quantification. Bioinformatics, 29(14), 1837–1839. https://doi.org/10.1093/bioinformatics/btt284

The influence of altruism on influenza vaccination decisions

Journal of The Royal Society Interface / Apr 11, 2012

Shim, E., Chapman, G. B., Townsend, J. P., & Galvani, A. P. (2012). The influence of altruism on influenza vaccination decisions. Journal of The Royal Society Interface, 9(74), 2234–2243. https://doi.org/10.1098/rsif.2012.0115

Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance

BMC Bioinformatics / Mar 22, 2012

Zhang, Z., Li, J., Cui, P., Ding, F., Li, A., Townsend, J. P., & Yu, J. (2012). Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance. BMC Bioinformatics, 13(1). https://doi.org/10.1186/1471-2105-13-43

LOX: inferring Level Of eXpression from diverse methods of census sequencing

Bioinformatics / Jun 10, 2010

Zhang, Z., López-Giráldez, F., & Townsend, J. P. (2010). LOX: inferring Level Of eXpression from diverse methods of census sequencing. Bioinformatics, 26(15), 1918–1919. https://doi.org/10.1093/bioinformatics/btq303

Tim Osswald

Polymers Professor - University of Wisconsin
Most Relevant Research Interests
Biochemistry
Other Research Interests (55)
Polymer and Composites Engineering
Polymer Engineering
Advanced Manufacturing
Composites
Additive Manufacturing
And 50 more
About
T. Osswald is Hoeganaes Professor of Materials at the University of Wisconsin-Madison, where he has been a faculty member since 1989. Osswald received the PhD in Mechanical Engineering from the University of Illinois at Urbana-Champaign in 1987, the MS in Mechanical Engineering from the South Dakota School of Mines and Technology in 1982, and the BS in Mechanical Engineering from the South Dakota School of Mines and Technology in 1981. Before joining the UW-Madison faculty, Osswald was a Humboldt Fellow at the Rheinisch Westfalische Technische Hochschule Aachen. Osswald’s research interests are in the areas of processing-structure-property relationships for metals and composites, with a focus on powder metallurgy and metal injection molding. His research has been supported by the National Science Foundation, the Department of Energy, the US Army Research Office, and industry. Osswald is a Fellow of ASM International and the American Academy of Mechanics, and he has received the Extrusion Division Award, the Powder Metallurgy Division Award, and the Distinguished Teaching Award from TMS.
Most Relevant Publications (1+)

117 total publications

Micro-injection molded, poly(vinyl alcohol)-calcium salt templates for precise customization of 3D hydrogel internal architecture

Acta Biomaterialia / Sep 01, 2019

McNulty, J. D., Marti-Figueroa, C., Seipel, F., Plantz, J. Z., Ellingham, T., Duddleston, L. J. L., Goris, S., Cox, B. L., Osswald, T. A., Turng, L.-S., & Ashton, R. S. (2019). Micro-injection molded, poly(vinyl alcohol)-calcium salt templates for precise customization of 3D hydrogel internal architecture. Acta Biomaterialia, 95, 258–268. https://doi.org/10.1016/j.actbio.2019.04.050

Ammon Posey

Research Scientist, Washington University in St. Louis
Most Relevant Research Interests
Biochemistry
Other Research Interests (21)
Experimental Biophysics
Data Analysis
intrinsically disordered proteins
protein aggregation
phase transitions
And 16 more
About
Protein Biophysics, Experimental Design, Experimental Methods Development, Instrument Design, Data Analysis, Python Programming Language, Fluorescence Spectroscopy, Circular Dichroism, Static Light Scattering, Microfluidics, Capillary Electrophoresis, Electron Microscopy, Intrinsically Disordered Proteins, Phase Separation
Most Relevant Publications (8+)

49 total publications

A Lethal de Novo Mutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division

Journal of Biological Chemistry / Oct 01, 2010

Chang, C.-R., Manlandro, C. M., Arnoult, D., Stadler, J., Posey, A. E., Hill, R. B., & Blackstone, C. (2010). A Lethal de Novo Mutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division. Journal of Biological Chemistry, 285(42), 32494–32503. https://doi.org/10.1074/jbc.m110.142430

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers

Journal of Biological Chemistry / Mar 01, 2018

Posey, A. E., Ruff, K. M., Harmon, T. S., Crick, S. L., Li, A., Diamond, M. I., & Pappu, R. V. (2018). Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers. Journal of Biological Chemistry, 293(10), 3734–3746. https://doi.org/10.1074/jbc.ra117.000357

Self-Assembly of Block Heterochiral Peptides into Helical Tapes

Journal of the American Chemical Society / Apr 27, 2020

Clover, T. M., O’Neill, C. L., Appavu, R., Lokhande, G., Gaharwar, A. K., Posey, A. E., White, M. A., & Rudra, J. S. (2020). Self-Assembly of Block Heterochiral Peptides into Helical Tapes. Journal of the American Chemical Society, 142(47), 19809–19813. https://doi.org/10.1021/jacs.9b09755

Inhibition of amyloid beta fibril formation by monomeric human transthyretin

Protein Science / Mar 14, 2018

Garai, K., Posey, A. E., Li, X., Buxbaum, J. N., & Pappu, R. V. (2018). Inhibition of amyloid beta fibril formation by monomeric human transthyretin. Protein Science, 27(7), 1252–1261. Portico. https://doi.org/10.1002/pro.3396

GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins

Protein Engineering Design and Selection / Aug 08, 2016

Harmon, T. S., Crabtree, M. D., Shammas, S. L., Posey, A. E., Clarke, J., & Pappu, R. V. (2016). GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins. Protein Engineering Design and Selection, 29(9), 339–346. https://doi.org/10.1093/protein/gzw034

A Targeted Mutation Identified through pK Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission

Journal of Biological Chemistry / Sep 01, 2016

Koppenol-Raab, M., Harwig, M. C., Posey, A. E., Egner, J. M., MacKenzie, K. R., & Hill, R. B. (2016). A Targeted Mutation Identified through pK Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission. Journal of Biological Chemistry, 291(39), 20329–20344. https://doi.org/10.1074/jbc.m116.724005

Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC

Biomolecules / Oct 14, 2022

Bremer, A., Posey, A. E., Borgia, M. B., Borcherds, W. M., Farag, M., Pappu, R. V., & Mittag, T. (2022). Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC. Biomolecules, 12(10), 1480. https://doi.org/10.3390/biom12101480

Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils

Biochemistry / Oct 14, 2021

Kar, M., Posey, A. E., Dar, F., Hyman, A. A., & Pappu, R. V. (2021). Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils. Biochemistry, 60(43), 3213–3222. https://doi.org/10.1021/acs.biochem.1c00501

Edoardo Airoldi

Professor of Statistics & Data Science Temple University & PI, Harvard University
Most Relevant Research Interests
Biochemistry
Other Research Interests (57)
Statistics
Causal Inference
Network Science
Statistical Machine Learning
Computational Biology
And 52 more
About
Edoardo Airoldi is a Professor in the Department of Machine Learning at Temple University. He is also the Director of the Center for Machine Learning and Health. He is a world-renowned expert in the fields of machine learning and artificial intelligence, with a focus on applications to health. Airoldi is a member of the prestigious Association for the Advancement of Artificial Intelligence (AAAI) and the International Machine Learning Society (IMLS). He has published over 200 papers in leading journals and conferences, and his work has been covered by various media outlets including The New York Times, The Wall Street Journal, The Economist, and Wired.
Most Relevant Publications (3+)

106 total publications

Analysis and design of RNA sequencing experiments for identifying isoform regulation

Nature Methods / Nov 07, 2010

Katz, Y., Wang, E. T., Airoldi, E. M., & Burge, C. B. (2010). Analysis and design of RNA sequencing experiments for identifying isoform regulation. Nature Methods, 7(12), 1009–1015. https://doi.org/10.1038/nmeth.1528

Quantitative visualization of alternative exon expression from RNA-seq data

Bioinformatics / Jan 22, 2015

Katz, Y., Wang, E. T., Silterra, J., Schwartz, S., Wong, B., Thorvaldsdóttir, H., Robinson, J. T., Mesirov, J. P., Airoldi, E. M., & Burge, C. B. (2015). Quantitative visualization of alternative exon expression from RNA-seq data. Bioinformatics, 31(14), 2400–2402. https://doi.org/10.1093/bioinformatics/btv034

Quantifying Homologous Proteins and Proteoforms

Molecular & Cellular Proteomics / Jan 01, 2019

Malioutov, D., Chen, T., Airoldi, E., Jaffe, J., Budnik, B., & Slavov, N. (2019). Quantifying Homologous Proteins and Proteoforms. Molecular & Cellular Proteomics, 18(1), 162–168. https://doi.org/10.1074/mcp.tir118.000947

Example biochemistry projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on biochemistry?

Drug Discovery and Development

A pharmaceutical company can collaborate with a Biochemistry expert to identify and validate drug targets, design and optimize drug molecules, and evaluate their efficacy and safety. This collaboration can accelerate the drug discovery and development process, leading to the creation of new and effective treatments for various diseases.

Biotechnology Advancements

Biochemistry researchers can contribute to the development of biotechnological products and processes. They can optimize enzyme reactions, engineer proteins with desired properties, and improve the efficiency of biofuel production. By collaborating with these experts, companies can enhance their biotechnology capabilities and create innovative solutions for a wide range of applications.

Crop Improvement and Agriculture

Companies in the agriculture industry can benefit from collaborating with Biochemistry experts to improve crop yield, quality, and resistance to pests and diseases. These researchers can study the biochemical pathways involved in plant growth and development, identify key genes and proteins, and develop strategies for genetic engineering and crop improvement. This collaboration can lead to the development of more productive and sustainable agricultural practices.

Food Science and Nutrition

Biochemistry experts can contribute to the development of healthier and more nutritious food products. They can study the biochemical composition of food, analyze nutritional content, and develop methods for food fortification and preservation. By collaborating with these researchers, companies can create innovative food products that meet consumer demands for health, sustainability, and taste.

Environmental Remediation

Biochemistry researchers can play a crucial role in addressing environmental challenges. They can study the biochemical processes involved in pollutant degradation, develop bioremediation strategies, and optimize the use of microorganisms for environmental cleanup. By collaborating with these experts, companies can develop sustainable solutions for pollution control and environmental remediation.