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Work with thought leaders and academic experts in Biophysics

Companies can greatly benefit from working with experts in the field of Biophysics. These researchers bring a unique set of skills and knowledge that can contribute to various aspects of a company's operations. They can provide valuable insights and solutions in areas such as drug discovery, medical device development, bioinformatics, biotechnology, and more. By collaborating with Biophysics experts, companies can enhance their research capabilities, accelerate innovation, improve product development, and gain a competitive edge in the market.

Researchers on NotedSource with backgrounds in Biophysics include Aimee Eggler, Ramy Ayoub, Ajay Badhan, Ping Luo, Dr. David Siderovski, Ph.D., Michael W Harman, Dr. Shilpa Patil, Ph.D, Nicolangelo Iannella, and Martin Tsui.

Aimee Eggler

Villanova, Pennsylvania, United States of America
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Expertise
Biophysics
Other Research Expertise (18)
Biochemistry
Physiology (medical)
Toxicology
Organic Chemistry
Clinical Biochemistry
And 13 more
About
Dr. Eggler has 20 years of experience in the field of redox biology, with a focus on the Nrf2 transcription factor, a master regulator of antioxidant, detoxification and anti-inflammatory genes. She is also an award-winning educator and the recipient of the Villanova University Junior Faculty Excellence in Teaching award. Her interests in education include innovation in teaching metabolism from a logic-based perspective.
Most Relevant Publications (3+)

25 total publications

Screening for natural chemoprevention agents that modify human Keap1

Analytical Biochemistry / Feb 01, 2012

Hu, C., Nikolic, D., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2012). Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry, 421(1), 108–114. https://doi.org/10.1016/j.ab.2011.10.028

Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1

Biochemical and Biophysical Research Communications / Oct 01, 2010

Small, E., Eggler, A., & Mesecar, A. D. (2010). Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1. Biochemical and Biophysical Research Communications, 400(4), 471–475. https://doi.org/10.1016/j.bbrc.2010.08.062

The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides

Archives of Biochemistry and Biophysics / Nov 01, 2008

McAdams, K., Casper, E. S., Matthew Haas, R., Santarsiero, B. D., Eggler, A. L., Mesecar, A., & Halkides, C. J. (2008). The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides. Archives of Biochemistry and Biophysics, 479(2), 105–113. https://doi.org/10.1016/j.abb.2008.08.019

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Ramy Ayoub

Toronto, Ontario, Canada
PhD Medical Biophysics
Most Relevant Research Expertise
Biophysics
Other Research Expertise (10)
neuro-oncology
mouse imaging
cancer therapy
normal tissue toxicity
Radiology, Nuclear Medicine and imaging
And 5 more
About
Ramy Ayoub obtained his Ph.D. in Medical Biophysics from the University of Toronto in 2023, where he developed a strong foundation in the principles and applications in neuroscience, statistics, machine learning, imaging & radiation physics. During his time at the University of Toronto, Ramy has been involved in conducting cutting-edge research in the field, with a focus on developing new technologies and pharmacological interventions to improve healthcare outcomes. He is passionate about using his skills and expertise to make a positive impact in the medical field and is dedicated to advancing the field through his ongoing research and contributions.
Most Relevant Publications (1+)

7 total publications

Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation

Radiation Research / Jul 16, 2021

Ayoub, R., Lau, K., Yuen, N., Fernandes, D., Elder, M., Yeung, J., Wong, S. C., & Nieman, B. J. (2021). Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation. Radiation Research, 196(4). https://doi.org/10.1667/rade-21-00013.1

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Ajay Badhan

Lethbridge, Alberta, Canada
Research Biologist, Lethbridge Research Center, Canada
Most Relevant Research Expertise
Biophysics
Other Research Expertise (26)
Animal nutrition
cell wall biosynthesis and its deconstruction
biofuels
Waste Management and Disposal
Renewable Energy, Sustainability and the Environment
And 21 more
About
I am a proficient researcher with valuable research and teaching experience acquired at distinguished institutes like Complex Carbohydrate Research Center, US, University of Alberta, Canada, and Lethbridge Research Center (AAFC), Canada. I have been working for past 15 years on multiple projects focused on the economical, environmental and social sustainability of agricultural production. Improvement in livestock performance, productivity, and health by unlocking the microbiome, development of clean technologies, improving agriculture environmental performance, and Increase agro-ecosystem resilience are prime objectives for my research.
Most Relevant Publications (1+)

29 total publications

Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses

Computational and Structural Biotechnology Journal / Jan 01, 2022

Badhan, A., Low, K. E., Jones, D. R., Xing, X., Milani, M. R. M., Polo, R. O., Klassen, L., Venketachalam, S., Hahn, M. G., Abbott, D. W., & McAllister, T. A. (2022). Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses. Computational and Structural Biotechnology Journal, 20, 148–164. https://doi.org/10.1016/j.csbj.2021.12.009

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Ping Luo

Toronto, Ontario, Canada
Bioinformatics Specialist at Princess Margaret Cancer Centre with experience in deep learning
Most Relevant Research Expertise
Biophysics
Other Research Expertise (21)
single-cell genomics
deep learning
complex network analysis
Genetics (clinical)
Genetics
And 16 more
About
8 years of science and engineering experience integrating multi-omics data to identify biomarkers for cancer studies. Seeking to apply data analytics expertise to develop new diagnosis and treatment strategies.
Most Relevant Publications (1+)

23 total publications

Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets

Computational and Structural Biotechnology Journal / Jan 01, 2022

Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029

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Dr. David Siderovski, Ph.D.

Fort Worth
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Most Relevant Research Expertise
Biophysics
Other Research Expertise (25)
Regulator of G protein Signaling (RGS) proteins
Pharmacology
Molecular Biology
Cellular and Molecular Neuroscience
Molecular Medicine
And 20 more
About
Dr. David Siderovski is a renowned scientist and academic, with a career spanning over two decades. He received his Ph.D. in Medical Biophysics from the University of Toronto in 1997, where he specialized in signal transduction and cellular signaling pathways. After completing his doctorate, Dr. Siderovski held various faculty positions at prestigious universities, including the University of North Carolina at Chapel Hill, West Virginia University School of Medicine, and the University of North Texas Health Science Center. At these institutions, Dr. Siderovski has made significant contributions to the field of pharmacology through his research on G protein-coupled receptors (GPCRs) and RGS proteins, which are key regulators of GPCR cellular signaling. His work has helped to advance the understanding of RGS proteins and their roles in various diseases, including cancer, cardiovascular disorders, and neurological disorders. In addition to his research, Dr. Siderovski is also a dedicated educator and mentor. He has taught and mentored numerous undergraduate, graduate, and medical students, and has served as a mentor for postdoctoral fellows and junior faculty members. He is known for his passion and enthusiasm for science and his ability to inspire and guide the next generation of scientists. Dr. Siderovski has received numerous awards and honors for his contributions to the scientific community. He was the recipient of the Abel Award in 2004 from the American Society of Pharmacology & Experimental Therapeutics for his pioneering discoveries of the RGS proteins and the GoLoco motif. He has also served on editorial boards of several scientific journals (including a decade at *J.Biol.Chem.*) and has been a member of various scientific committees, NIH study section panels, and pharma/biotech advisory boards, including for Inspire, Wyeth, and BellBrook Labs. Overall, Dr. David Siderovski is a highly accomplished and respected scientist and educator, whose research has had a significant impact on the field of pharmacology. His dedication and passion for science continue to inspire and influence the next generation of researchers in this field.
Most Relevant Publications (4+)

94 total publications

Molecular Cloning and Expression Analysis of RatRgs12andRgs14

Biochemical and Biophysical Research Communications / Apr 01, 1997

Snow, B. E., Antonio, L., Suggs, S., Gutstein, H. B., & Siderovski, D. P. (1997). Molecular Cloning and Expression Analysis of RatRgs12andRgs14. Biochemical and Biophysical Research Communications, 233(3), 770–777. https://doi.org/10.1006/bbrc.1997.6537

The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics / Sep 01, 2007

Kimple, A. J., Willard, F. S., Giguère, P. M., Johnston, C. A., Mocanu, V., & Siderovski, D. P. (2007). The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774(9), 1213–1220. https://doi.org/10.1016/j.bbapap.2007.06.002

A direct fluorescence-based assay for RGS domain GTPase accelerating activity

Analytical Biochemistry / May 01, 2005

Willard, F. S., Kimple, A. J., Johnston, C. A., & Siderovski, D. P. (2005). A direct fluorescence-based assay for RGS domain GTPase accelerating activity. Analytical Biochemistry, 340(2), 341–351. https://doi.org/10.1016/j.ab.2005.02.015

Covalent immobilization of histidine-tagged proteins for surface plasmon resonance

Analytical Biochemistry / Jun 01, 2006

Willard, F. S., & Siderovski, D. P. (2006). Covalent immobilization of histidine-tagged proteins for surface plasmon resonance. Analytical Biochemistry, 353(1), 147–149. https://doi.org/10.1016/j.ab.2006.02.004

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Michael W Harman

East Greenwich, RI, Rhode Island, United States of America
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Expertise
Biophysics
Other Research Expertise (13)
Bacteria & Cell Bio-Physics
Biomechanics
Infectious Diseases
Immunology
Microbiology
And 8 more
About
Highly skilled, energetic, and motivated professional empowered by over a decade of cross-disciplinary engineering and scientific applications experience. Presenting elegant solutions to prevalent biomedical challenges. Motivated by driving deliverable outcomes from complex research studies through effective leadership, active consulting work, and innovative problem-solving techniques. Seeking to make an immediate impact in a fast-paced biotechnology environment capitalizing on my advanced comprehension, continued professional growth, strategic product development expertise, and active network of personal connections across all areas of science, engineering, medicine, manufacturing and healthcare.
Most Relevant Publications (4+)

15 total publications

Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag

Biophysical Journal / Nov 01, 2013

Harman, M., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag. Biophysical Journal, 105(10), 2273–2280. https://doi.org/10.1016/j.bpj.2013.10.004

Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium

Biophysical Journal / Feb 01, 2017

Harman, M. W., Hamby, A. E., Boltyanskiy, R., Belperron, A. A., Bockenstedt, L. K., Kress, H., Dufresne, E. R., & Wolgemuth, C. W. (2017). Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium. Biophysical Journal, 112(4), 746–754. https://doi.org/10.1016/j.bpj.2016.12.039

Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels

Biophysical Journal / Feb 01, 2018

Harman, M. W., Franck, C., & Reichner, J. (2018). Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels. Biophysical Journal, 114(3), 324a. https://doi.org/10.1016/j.bpj.2017.11.1819

The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments

Biophysical Journal / Jan 01, 2013

Harman, M. W., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments. Biophysical Journal, 104(2), 638a–639a. https://doi.org/10.1016/j.bpj.2012.11.3526

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Dr. Shilpa Patil, Ph.D

Vancouver, British Columbia, Canada
PhD & Postdoc level expertise in Cancer Research
Most Relevant Research Expertise
Biophysics
Other Research Expertise (11)
Cancer
epigenetics
development
Oncology
Cancer Research
And 6 more
About
Dr. Shilpa Patil is a highly experienced cancer researcher with a strong background in Preclinical studies. She received her Ph.D. in Molecular Medicine from the University of Göttingen in 2020, where she focused on developing novel treatments for pancreatic cancer. Prior to that, she completed her MSc in Regenerative Medicine from Manipal University in 2014 and her BSc in Biotechnology from the same institution in 2012. With over 6 years of research experience, Dr. Patil has worked at prestigious institutions such as the University of British Columbia, University of Göttingen and JNCASR. Her expertise lies in the areas of cancer biology, epigenetics, cell and molecular biology, and regenerative medicine. She has published numerous research articles in reputed journals and has presented her work at various international conferences. Dr. Patil is a dedicated and passionate scientist, committed to using her knowledge and skills to contribute to the fight against cancer. She is driven by her curiosity to unravel complex biological processes and her desire to make a positive impact in the field of cancer research. She is also driven to bridge the academia-industry gap.
Most Relevant Publications (1+)

20 total publications

Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation

Biochimica et Biophysica Acta (BBA) - General Subjects / Aug 01, 2018

Kaypee, S., Sahadevan, S. A., Sudarshan, D., Halder Sinha, S., Patil, S., Senapati, P., Kodaganur, G. S., Mohiyuddin, A., Dasgupta, D., & Kundu, T. K. (2018). Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(8), 1729–1741. https://doi.org/10.1016/j.bbagen.2018.05.003

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Nicolangelo Iannella

Oslo
Senior Research fellow, The University of Oslo, Faculty of Mathematics and Natural Sciences
Most Relevant Research Expertise
Biophysics
Other Research Expertise (18)
Neuromorphic circuits
Neural networks, Neural learning and applications
Theoretical and Mathematical neuroscience
Computational neuroscience
Artificial Intelligence
And 13 more
About
Following pre-doctoral studies in Mathematics and Theoretical Physics, I received a PhD in Computational Neuroscience from the University of Electro-Communications, Japan in 2009. From 2009, I was a Postdoctoral Researcher in RIKEN BSI. In 2010, I won the prestigious Australian Research Council (ARC) Australian Postdoctoral Award (APD) fellowship, based at the University of Adelaide from 2010–2014. In 2012 he completed a Graduate Certificate in Education (Higher Education) (GCEHE) from the University of Adelaide. From 2014–2017 he was an adjunct research fellow at the University of South Australia. From 2016–2018, he was a Cascade (Marie Curie) Research Fellow in Mathematical Sciences at the University of Nottingham. From 2018- a research fellow at the University of Oslo. His research interests include AI, Artificial and spiking neural networks and learning algorithms, synaptic plasticity, neuronal dynamics, and neuromorphic engineering. Dr. Iannella is a member of SFN and a Senior member of the IEEE.
Most Relevant Publications (1+)

47 total publications

Time As a Geometric Property of Space

Frontiers in Physics / Nov 17, 2016

Chappell, J. M., Hartnett, J. G., Iannella, N., Iqbal, A., & Abbott, D. (2016). Time As a Geometric Property of Space. Frontiers in Physics, 4. https://doi.org/10.3389/fphy.2016.00044

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Martin Tsui

San Francisco, California, United States of America
University of California, San Francisco
Most Relevant Research Expertise
Biophysics
Other Research Expertise (15)
Biochemistry
Structural Biology
Cryo-EM
CRISPR
Molecular Assembly and Interaction
And 10 more
About
Martin Tsui is an accomplished scientist with a strong background in biochemistry. He received his Ph.D. in Molecular Biophysics from Florida State University in 2017, where he conducted research on the structure and function of CRISPR proteins. Prior to that, he obtained his B.S. in Chemistry from the University of California, San Diego in 2012. After completing his graduate studies, Martin founded his own company, Stealth, where he serves as a Founder & CEO. Under his leadership, the company has developed innovative solutions for the biotech industry and has gained recognition for its groundbreaking research. Before starting his company, Martin worked as a Senior Scientist at Amazon, where he applied his expertise in protein biochemistry and CRISPR to improve the company's product development processes and creating new products. He also gained valuable experience as a Postdoctoral Scholar at the University of California, San Francisco and Postdoctoral Fellow at the Van Andel Institute, where he studied cancer proteins, SARS-CoV-2, HIV proteins, and the role of proteins in neurodegenerative diseases, respectively. Martin is a highly driven and passionate individual who is dedicated to advancing the field of biotechnology. His impressive education and diverse experience have equipped him with the skills and knowledge to make significant contributions to the scientific community. He continues to pursue new opportunities to further his research and make a positive impact in the world of science.
Most Relevant Publications (2+)

16 total publications

Structure Principles of CRISPR-Cas Surveillance and Effector Complexes

Annual Review of Biophysics / Jun 22, 2015

Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939

The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9

Biophysical Journal / Feb 01, 2017

Kin Martin Tsui, T., Hand, T. H., & Li, H. (2017). The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9. Biophysical Journal, 112(3), 71a. https://doi.org/10.1016/j.bpj.2016.11.431

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Example Biophysics projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Biophysics?

Drug Discovery

A Biophysics expert can contribute to the development of new drugs by studying the interactions between molecules and biological systems. They can provide insights into the structure and function of proteins, identify potential drug targets, and optimize drug candidates for efficacy and safety.

Medical Device Development

Biophysics researchers can play a crucial role in the development of medical devices. They can apply their knowledge of biophysical principles to design and optimize devices such as biosensors, imaging systems, and prosthetics. Their expertise can ensure the accuracy, sensitivity, and reliability of these devices.

Bioinformatics

Biophysics experts can contribute to the field of bioinformatics by analyzing and interpreting large-scale biological data. They can develop computational models and algorithms to study complex biological systems, predict protein structures, and analyze genomic data. Their expertise can help companies extract valuable insights from big data and make informed decisions.

Biotechnology

Biophysics researchers can contribute to the advancement of biotechnology by applying their knowledge of physical and chemical principles to manipulate biological systems. They can develop innovative techniques for gene editing, protein engineering, and biomaterial synthesis. Their expertise can drive breakthroughs in areas such as personalized medicine, agriculture, and renewable energy.

Biophysical Characterization

Companies can benefit from collaborating with Biophysics experts for the characterization of biomolecules and biological systems. They can use techniques such as spectroscopy, microscopy, and mass spectrometry to study the structure, dynamics, and interactions of biomolecules. This information is crucial for understanding disease mechanisms, optimizing drug formulations, and improving the performance of biotechnological processes.