Work with thought leaders and academic experts in Biophysics
Companies can greatly benefit from working with experts in the field of Biophysics. These researchers bring a unique set of skills and knowledge that can contribute to various aspects of a company's operations. They can provide valuable insights and solutions in areas such as drug discovery, medical device development, bioinformatics, biotechnology, and more. By collaborating with Biophysics experts, companies can enhance their research capabilities, accelerate innovation, improve product development, and gain a competitive edge in the market.
Researchers on NotedSource with backgrounds in Biophysics include Aimee Eggler, Ramy Ayoub, Dr. Shilpa Patil, Ph.D, Dr. rer. nat. Rudrarup Bose, Ping Luo, Martin Tsui, Michael W Harman, Nicolangelo Iannella, Dr. David Siderovski, Ph.D., David Proctor, and Ajay Badhan.
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
Education
University of California, Santa Cruz
BS, Chemistry / May, 1996
University of Wisconsin–Madison
Ph.D., Biochemistry / May, 2002
Experience
Villanova University
Associate Professor of Chemistry / 2019 — Present
Villanova University
Assistant Professor / 2012 — 2019
Purdue University
Research Assistant Professor / 2010 — 2012
Most Relevant Research Expertise
Other Research Expertise (18)
About
Most Relevant Publications (3+)
25 total publications
Screening for natural chemoprevention agents that modify human Keap1
Analytical Biochemistry / Feb 01, 2012
Hu, C., Nikolic, D., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2012). Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry, 421(1), 108–114. https://doi.org/10.1016/j.ab.2011.10.028
Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1
Biochemical and Biophysical Research Communications / Oct 01, 2010
Small, E., Eggler, A., & Mesecar, A. D. (2010). Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1. Biochemical and Biophysical Research Communications, 400(4), 471–475. https://doi.org/10.1016/j.bbrc.2010.08.062
The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides
Archives of Biochemistry and Biophysics / Nov 01, 2008
McAdams, K., Casper, E. S., Matthew Haas, R., Santarsiero, B. D., Eggler, A. L., Mesecar, A., & Halkides, C. J. (2008). The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides. Archives of Biochemistry and Biophysics, 479(2), 105–113. https://doi.org/10.1016/j.abb.2008.08.019
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Ramy Ayoub
PhD Medical Biophysics
Education
University of Toronto
Ph.D., Medical Biophysics / October, 2023 (anticipated)
Experience
The Hospital for Sick Children
PhD Scientific Researcher / September, 2018 — October, 2023
Designed strategies to limit negative complications experienced by brain tumour survivors treated with radiation; Conducted genetic and pharmacological interventions in mouse models to determine translatability of strategies; Assessed the efficacy of treatment strategies using multi-modal imaging approaches (MRI, serial two-photon imaging); Published findings in peer-reviewed journals Nature, and Radiation Research
Most Relevant Research Expertise
Other Research Expertise (10)
About
Most Relevant Publications (1+)
7 total publications
Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation
Radiation Research / Jul 16, 2021
Ayoub, R., Lau, K., Yuen, N., Fernandes, D., Elder, M., Yeung, J., Wong, S. C., & Nieman, B. J. (2021). Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation. Radiation Research, 196(4). https://doi.org/10.1667/rade-21-00013.1
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Dr. Shilpa Patil, Ph.D
PhD & Postdoc level expertise in Cancer Research
Education
University of Göttingen
Ph.D, Cancer Research / June, 2020
Manipal Academy of Higher Education
MSc, Regenerative Medicine / August, 2014
Manipal Academy of Higher Education
BSc, Biotechnology / August, 2012
Experience
University of British Columbia
Postdoctoral Research Fellow / January, 2021 — July, 2023
University of Gottingen
Postdoctoral Researcher / July, 2020 — December, 2020
JNCASR
Research Assistant / September, 2014 — February, 2016
Most Relevant Research Expertise
Other Research Expertise (11)
About
Most Relevant Publications (1+)
20 total publications
Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation
Biochimica et Biophysica Acta (BBA) - General Subjects / Aug 01, 2018
Kaypee, S., Sahadevan, S. A., Sudarshan, D., Halder Sinha, S., Patil, S., Senapati, P., Kodaganur, G. S., Mohiyuddin, A., Dasgupta, D., & Kundu, T. K. (2018). Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(8), 1729–1741. https://doi.org/10.1016/j.bbagen.2018.05.003
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Ping Luo
Assistant Professor at Algoma University
Education
University of Saskatchewan
Ph.D., Biomedical Engineering / September, 2019
Beijing Institute of Technology
M.Eng., Biomedical Engineering / June, 2015
Hunan University
B.Eng., Computer Science / June, 2010
Experience
Princess Margaret Cancer Centre
Postdoctoral Researcher / November, 2019 — Present
I work in Dr. Trevor Pugh's lab and design cancer diagnosis and treatment strategies by analyze cell-free DNA and single cell sequencing data
Princess Margaret Cancer Centre
Bioinformatics Specialist / September, 2023 — Present
I work in Dr. Tak Mak's lab and study tumor immunology using single cell and TCR sequencing data.
Most Relevant Research Expertise
Other Research Expertise (21)
About
Most Relevant Publications (1+)
23 total publications
Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets
Computational and Structural Biotechnology Journal / Jan 01, 2022
Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029
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Martin Tsui
University of California, San Francisco
Education
Florida State University
Ph.D., Molecular Biophysics / July, 2017
University of California, San Diego
B.S., Chemistry / June, 2012
Experience
Stealth
Founder & CEO / January, 2023 — Present
Genome engineering
Amazon
Senior Scientist / December, 2021 — February, 2023
Molecular Diagnostics
Van Andel Institute
Postdoctoral Fellow / September, 2020 — April, 2021
Cryo-EM of membrane proteins
Most Relevant Research Expertise
Other Research Expertise (15)
About
Most Relevant Publications (2+)
16 total publications
Structure Principles of CRISPR-Cas Surveillance and Effector Complexes
Annual Review of Biophysics / Jun 22, 2015
Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939
The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9
Biophysical Journal / Feb 01, 2017
Kin Martin Tsui, T., Hand, T. H., & Li, H. (2017). The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9. Biophysical Journal, 112(3), 71a. https://doi.org/10.1016/j.bpj.2016.11.431
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Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Education
University of Connecticut
BS, Biomedical Engineering, Biofluid Mechanics Track / May, 2008
University of Connecticut
MS, Biomedical Engineering, Biomechanics Concentration / December, 2009
University of Arizona
Ph.D, Biochemistry, Molecular and Cellular Biology / December, 2015
Experience
Brown University
Postdoctoral Research Fellow / May, 2016 — August, 2018
Critical lead asset driving preclinical collaborative cell biomechanics study managing 30 personnel between immunology, pathobiology, and experimental soft matter mechanics laboratories.
Rhode Island Hospital
Postdoctoral Research Fellow / May, 2016 — August, 2018
Critical lead asset driving preclinical collaborative cell biomechanics study managing 30 personnel between immunology, pathobiology, and experimental soft matter mechanics laboratories.
Ximedica
Research & Development Engineer / September, 2018 — October, 2019
Provided technical subject matter expertise to enhance the clinical performance of novel medical products being designed.
Research & Development Engineering Manager / October, 2019 — July, 2020
Grew a team of Research & Development Engineers out of our traditional designer, mechanical, and electrical engineering departments to form a novel team within the organization and supported each of their individual professional development needs.
Most Relevant Research Expertise
Other Research Expertise (13)
About
Most Relevant Publications (4+)
15 total publications
Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag
Biophysical Journal / Nov 01, 2013
Harman, M., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag. Biophysical Journal, 105(10), 2273–2280. https://doi.org/10.1016/j.bpj.2013.10.004
Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium
Biophysical Journal / Feb 01, 2017
Harman, M. W., Hamby, A. E., Boltyanskiy, R., Belperron, A. A., Bockenstedt, L. K., Kress, H., Dufresne, E. R., & Wolgemuth, C. W. (2017). Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium. Biophysical Journal, 112(4), 746–754. https://doi.org/10.1016/j.bpj.2016.12.039
Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels
Biophysical Journal / Feb 01, 2018
Harman, M. W., Franck, C., & Reichner, J. (2018). Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels. Biophysical Journal, 114(3), 324a. https://doi.org/10.1016/j.bpj.2017.11.1819
The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments
Biophysical Journal / Jan 01, 2013
Harman, M. W., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments. Biophysical Journal, 104(2), 638a–639a. https://doi.org/10.1016/j.bpj.2012.11.3526
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Nicolangelo Iannella
Senior Research fellow, The University of Oslo, Faculty of Mathematics and Natural Sciences
Education
University of Adelaide
Graduate Certificate in Education (Higher Education) , School of Electrical & Electronic engineering / December, 2012
Denki Tsushin Daigaku
PhD (Eng), Information and Communications Engineering / March, 2009
Experience
University of Oslo
Postdoctoral Fellow / July, 2018 — Present
Most Relevant Research Expertise
Other Research Expertise (18)
About
Most Relevant Publications (1+)
47 total publications
Time As a Geometric Property of Space
Frontiers in Physics / Nov 17, 2016
Chappell, J. M., Hartnett, J. G., Iannella, N., Iqbal, A., & Abbott, D. (2016). Time As a Geometric Property of Space. Frontiers in Physics, 4. https://doi.org/10.3389/fphy.2016.00044
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Dr. David Siderovski, Ph.D.
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Education
University of Toronto
Ph.D., Medical Biophysics / November, 1997
Experience
University of North Carolina at Chapel Hill
Professor / January, 1999 — June, 2012
West Virginia University School of Medicine
E.J. Van Liere Endowed Medicine Professor and Chairman / July, 2012 — February, 2020
Chair of the Dept. of Physiology and Pharmacology
University of North Texas Health Science Center
Professor & Chair / March, 2020 — Present
Most Relevant Research Expertise
Other Research Expertise (25)
About
Most Relevant Publications (4+)
94 total publications
Molecular Cloning and Expression Analysis of RatRgs12andRgs14
Biochemical and Biophysical Research Communications / Apr 01, 1997
Snow, B. E., Antonio, L., Suggs, S., Gutstein, H. B., & Siderovski, D. P. (1997). Molecular Cloning and Expression Analysis of RatRgs12andRgs14. Biochemical and Biophysical Research Communications, 233(3), 770–777. https://doi.org/10.1006/bbrc.1997.6537
The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics / Sep 01, 2007
Kimple, A. J., Willard, F. S., Giguère, P. M., Johnston, C. A., Mocanu, V., & Siderovski, D. P. (2007). The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774(9), 1213–1220. https://doi.org/10.1016/j.bbapap.2007.06.002
A direct fluorescence-based assay for RGS domain GTPase accelerating activity
Analytical Biochemistry / May 01, 2005
Willard, F. S., Kimple, A. J., Johnston, C. A., & Siderovski, D. P. (2005). A direct fluorescence-based assay for RGS domain GTPase accelerating activity. Analytical Biochemistry, 340(2), 341–351. https://doi.org/10.1016/j.ab.2005.02.015
Covalent immobilization of histidine-tagged proteins for surface plasmon resonance
Analytical Biochemistry / Jun 01, 2006
Willard, F. S., & Siderovski, D. P. (2006). Covalent immobilization of histidine-tagged proteins for surface plasmon resonance. Analytical Biochemistry, 353(1), 147–149. https://doi.org/10.1016/j.ab.2006.02.004
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Ajay Badhan
Research Biologist, Lethbridge Research Center, Canada
Education
Ph.D., Microbiology
Experience
Agriculture Agri-food Canada
Biologist / May, 2015 — Present
Most Relevant Research Expertise
Other Research Expertise (26)
About
Most Relevant Publications (1+)
29 total publications
Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses
Computational and Structural Biotechnology Journal / Jan 01, 2022
Badhan, A., Low, K. E., Jones, D. R., Xing, X., Milani, M. R. M., Polo, R. O., Klassen, L., Venketachalam, S., Hahn, M. G., Abbott, D. W., & McAllister, T. A. (2022). Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses. Computational and Structural Biotechnology Journal, 20, 148–164. https://doi.org/10.1016/j.csbj.2021.12.009
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Example Biophysics projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Biophysics?
Drug Discovery
A Biophysics expert can contribute to the development of new drugs by studying the interactions between molecules and biological systems. They can provide insights into the structure and function of proteins, identify potential drug targets, and optimize drug candidates for efficacy and safety.
Medical Device Development
Biophysics researchers can play a crucial role in the development of medical devices. They can apply their knowledge of biophysical principles to design and optimize devices such as biosensors, imaging systems, and prosthetics. Their expertise can ensure the accuracy, sensitivity, and reliability of these devices.
Bioinformatics
Biophysics experts can contribute to the field of bioinformatics by analyzing and interpreting large-scale biological data. They can develop computational models and algorithms to study complex biological systems, predict protein structures, and analyze genomic data. Their expertise can help companies extract valuable insights from big data and make informed decisions.
Biotechnology
Biophysics researchers can contribute to the advancement of biotechnology by applying their knowledge of physical and chemical principles to manipulate biological systems. They can develop innovative techniques for gene editing, protein engineering, and biomaterial synthesis. Their expertise can drive breakthroughs in areas such as personalized medicine, agriculture, and renewable energy.
Biophysical Characterization
Companies can benefit from collaborating with Biophysics experts for the characterization of biomolecules and biological systems. They can use techniques such as spectroscopy, microscopy, and mass spectrometry to study the structure, dynamics, and interactions of biomolecules. This information is crucial for understanding disease mechanisms, optimizing drug formulations, and improving the performance of biotechnological processes.