Work with thought leaders and academic experts in Cell Biology
Companies can greatly benefit from working with experts in the field of Cell Biology. These researchers can provide valuable insights and expertise to enhance research and development efforts. They can help in developing innovative solutions and technologies, improving product quality and safety, and optimizing manufacturing processes. Additionally, collaborating with Cell Biology experts can lead to the discovery of new applications and opportunities in various industries such as pharmaceuticals, biotechnology, agriculture, and environmental sciences. By leveraging their knowledge and skills, companies can gain a competitive edge, accelerate scientific advancements, and drive business growth.
Researchers on NotedSource with backgrounds in Cell Biology include Boris Leibovitch, Michael W Harman, Regan Hamel, Sheed Itaman, Dr. Hannah Actor-Engel, Ph.D., Luca Delfinis, Burcu Vitrinel, Ph.D., John M Baust, Ph.D, Denver Ncube, Ph.D., THANGASAMY SAMINATHAN, Dr. David Siderovski, Ph.D., Martin Tsui, and Odion Ikhimiukor.
Boris Leibovitch
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Education
Moscow Region State University
PhD, Molecular Biology / April, 1978
Moscow Region State University
MS, Genetics / July, 1972
Moscow Region State University
BS, Genetics / April, 1971
Experience
NYU Langone Medical Center
Associate Research Scientist / June, 2021 — September, 2022
Wet lab research and teaching Molecular and Cell Biology in MD program
Icahn School of Medicine at Mount Sinai
Assistant Professor / July, 2004 — June, 2021
Wet lab research and teaching Molecular and Cell Biology in MD program
Washington University in St. Louis
Post-doctoral Research Associate / June, 1994 — June, 2004
Wet lab research and teaching Molecular and Cell Biology in MS program
Most Relevant Research Expertise
Other Research Expertise (8)
About
Most Relevant Publications (3+)
22 total publications
Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors
Developmental Biology / Jan 01, 2011
Marzan, C. V., Kupumbati, T. S., Bertran, S. P., Samuels, T., Leibovitch, B., Mira-y-Lopez, R., Ossowski, L., & Farias, E. F. (2011). Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors. Developmental Biology, 349(2), 125–136. https://doi.org/10.1016/j.ydbio.2010.10.018
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
Blood / Mar 15, 2008
Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122
GAGA Factor and the TFIID Complex Collaborate in Generating an Open Chromatin Structure at the Drosophila melanogaster hsp26 Promoter
Molecular and Cellular Biology / Sep 01, 2002
Leibovitch, B. A., Lu, Q., Benjamin, L. R., Liu, Y., Gilmour, D. S., & Elgin, S. C. R. (2002). GAGA Factor and the TFIID Complex Collaborate in Generating an Open Chromatin Structure at the Drosophila melanogaster hsp26 Promoter. Molecular and Cellular Biology, 22(17), 6148–6157. https://doi.org/10.1128/mcb.22.17.6148-6157.2002
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Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Education
University of Connecticut
BS, Biomedical Engineering, Biofluid Mechanics Track / May, 2008
University of Connecticut
MS, Biomedical Engineering, Biomechanics Concentration / December, 2009
University of Arizona
Ph.D, Biochemistry, Molecular and Cellular Biology / December, 2015
Experience
Brown University
Postdoctoral Research Fellow / May, 2016 — August, 2018
Critical lead asset driving preclinical collaborative cell biomechanics study managing 30 personnel between immunology, pathobiology, and experimental soft matter mechanics laboratories.
Rhode Island Hospital
Postdoctoral Research Fellow / May, 2016 — August, 2018
Critical lead asset driving preclinical collaborative cell biomechanics study managing 30 personnel between immunology, pathobiology, and experimental soft matter mechanics laboratories.
Ximedica
Research & Development Engineer / September, 2018 — October, 2019
Provided technical subject matter expertise to enhance the clinical performance of novel medical products being designed.
Research & Development Engineering Manager / October, 2019 — July, 2020
Grew a team of Research & Development Engineers out of our traditional designer, mechanical, and electrical engineering departments to form a novel team within the organization and supported each of their individual professional development needs.
Most Relevant Research Expertise
Other Research Expertise (13)
About
Most Relevant Publications (1+)
15 total publications
Measuring DNA content in live cells by fluorescence microscopy
Cell Division / Sep 04, 2018
Gomes, C. J., Harman, M. W., Centuori, S. M., Wolgemuth, C. W., & Martinez, J. D. (2018). Measuring DNA content in live cells by fluorescence microscopy. Cell Division, 13(1). https://doi.org/10.1186/s13008-018-0039-z
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Regan Hamel
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
Education
University of Cambridge
PhD, Clinical Neurosciences / September, 2021
University of Cambridge
MPhil, Clinical Neurosciences / September, 2018
McGill University
Bachelor of Science, Neurosciences / June, 2017
Experience
Mogrify Ltd
Bioinformatics scientist / August, 2021 — June, 2023
Senior Bioinformatics Scientist / July, 2023 — Present
Most Relevant Research Expertise
Other Research Expertise (12)
About
Most Relevant Publications (1+)
12 total publications
Stem Cell Therapies for Progressive Multiple Sclerosis
Frontiers in Cell and Developmental Biology / Jul 09, 2021
Smith, J. A., Nicaise, A. M., Ionescu, R.-B., Hamel, R., Peruzzotti-Jametti, L., & Pluchino, S. (2021). Stem Cell Therapies for Progressive Multiple Sclerosis. Frontiers in Cell and Developmental Biology, 9. https://doi.org/10.3389/fcell.2021.696434
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Dr. Hannah Actor-Engel, Ph.D.
University of Colorado Anschutz
Education
University of Colorado Denver
PhD, Neuroscience / 2023
New York University
Bachelor of Science, Neural Science / May, 2015
Experience
New York University
Junior Research Scientist / August, 2015 — May, 2017
Most Relevant Research Expertise
Other Research Expertise (5)
About
Most Relevant Publications (1+)
8 total publications
α4-GABAA receptors of hippocampal pyramidal neurons are associated with resilience against activity-based anorexia for adolescent female mice but not for males
Molecular and Cellular Neuroscience / Jul 01, 2018
Chen, Y.-W., Actor-Engel, H., & Aoki, C. (2018). α4-GABAA receptors of hippocampal pyramidal neurons are associated with resilience against activity-based anorexia for adolescent female mice but not for males. Molecular and Cellular Neuroscience, 90, 33–48. https://doi.org/10.1016/j.mcn.2018.04.008
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Luca Delfinis
PhD candidate in physiology researching the mechanisms that drive muscle dysfunction in cancer
Education
Wilfrid Laurier University
BSc, Kinesiology & Physical Education / April, 2018
York University
MSc, Molecular, Cellular and Integrative Physiology / August, 2020
York University
PhD, Molecular, Cellular and Integrative Physiology / August, 2024 (anticipated)
Experience
York University
Teaching Assistant / September, 2018 — Present
KINE 2049 (Research Methods in Kinesiology) and KINE 3012 (Human Physiology II)
Wilfrid Laurier University
Supplemental Instruction Senior Mentor / April, 2017 — April, 2018
Oversee teaching assistants with their teaching programs
Most Relevant Research Expertise
Other Research Expertise (2)
About
Most Relevant Publications (1+)
4 total publications
Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime
American Journal of Physiology-Cell Physiology / May 01, 2023
Bellissimo, C. A., Delfinis, L. J., Hughes, M. C., Turnbull, P. C., Gandhi, S., DiBenedetto, S. N., Rahman, F. A., Tadi, P., Amaral, C. A., Dehghani, A., Cobley, J. N., Quadrilatero, J., Schlattner, U., & Perry, C. G. R. (2023). Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime. American Journal of Physiology-Cell Physiology, 324(5), C1141–C1157. https://doi.org/10.1152/ajpcell.00377.2022
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Burcu Vitrinel, Ph.D.
Cross-functional life sciences strategy professional with a Ph.D. in genetics
Education
New York University
Ph.D., Developmental Genetics / May, 2021
M.Sc., Molecular Medicine / September, 2015
Sabancı University
B.Sc., Bioengineering / May, 2013
Experience
Putnam Associates
Life Sciences Consultant / July, 2021 — November, 2023
Most Relevant Research Expertise
Other Research Expertise (15)
About
Most Relevant Publications (2+)
10 total publications
Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity
Cell Systems / Dec 01, 2020
Shim, W. J., Sinniah, E., Xu, J., Vitrinel, B., Alexanian, M., Andreoletti, G., Shen, S., Sun, Y., Balderson, B., Boix, C., Peng, G., Jing, N., Wang, Y., Kellis, M., Tam, P. P. L., Smith, A., Piper, M., Christiaen, L., Nguyen, Q., … Palpant, N. J. (2020). Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity. Cell Systems, 11(6), 625-639.e13. https://doi.org/10.1016/j.cels.2020.11.001
The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans
Aging Cell / Aug 09, 2019
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A., & Tursun, B. (2019). The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Aging Cell, 18(6). Portico. https://doi.org/10.1111/acel.13012
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John M Baust, Ph.D
Proven success in delivering best-in-class services across scientific, commercial and education environments.
Education
Harvard Medical School
Post Doc
Binghamton University
Ph.D.
Cornell University
BS
Experience
Cell Preservation Services (United States)
President
Most Relevant Research Expertise
Other Research Expertise (16)
About
Most Relevant Publications (18+)
68 total publications
Molecular Mechanisms of Cellular Demise Associated with Cryopreservation Failure
Cell Preservation Technology / May 01, 2002
Baust, J. M. (2002). Molecular Mechanisms of Cellular Demise Associated with Cryopreservation Failure. Cell Preservation Technology, 1(1), 17–31. https://doi.org/10.1089/15383440260073266
Gene Activation of the Apoptotic Caspase Cascade Following Cryogenic Storage
Cell Preservation Technology / May 01, 2002
Baust, J. M., Van Buskirk, R., & Baust, J. G. (2002). Gene Activation of the Apoptotic Caspase Cascade Following Cryogenic Storage. Cell Preservation Technology, 1(1), 63–80. https://doi.org/10.1089/15383440260073301
Transplantation Diagnostics: A Preliminary Analysis Using Protein Microarray to Determine Kidney Status Prior To and Following Implantation
Cell Preservation Technology / Jun 01, 2004
Baust, J. M., Mathew, A. J., Snyder, K. K., Liu, E. H., van Buskirk, R. G., Hardy, M. A., & Baust, J. G. (2004). Transplantation Diagnostics: A Preliminary Analysis Using Protein Microarray to Determine Kidney Status Prior To and Following Implantation. Cell Preservation Technology, 2(2), 81–90. https://doi.org/10.1089/153834404774101936
Long-Term Function of Cryopreserved Rat Hepatocytes in a Coculture System
Cell Transplantation / Mar 01, 2004
Sugimachi, K., Sosef, M. N., Baust, J. M., Fowler, A., Tompkins, R. G., & Toner, M. (2004). Long-Term Function of Cryopreserved Rat Hepatocytes in a Coculture System. Cell Transplantation, 13(2), 187–195. https://doi.org/10.3727/000000004773301799
Cellular Components of the Coronary Vasculature Exhibit Differential Sensitivity to Low Temperature Insult
Cell Preservation Technology / Dec 01, 2002
Hollister, W. R., Baust, J. M., Van Buskirk, R. G., & Baust, J. G. (2002). Cellular Components of the Coronary Vasculature Exhibit Differential Sensitivity to Low Temperature Insult. Cell Preservation Technology, 1(4), 269–280. https://doi.org/10.1089/15383440260682099
Effect of Cell Substrate Interactions on the Desiccation Behavior of Human Fibroblasts
Cell Preservation Technology / Sep 01, 2004
Baust, J. M., Fowler, A., & Toner, M. (2004). Effect of Cell Substrate Interactions on the Desiccation Behavior of Human Fibroblasts. Cell Preservation Technology, 2(3), 188–197. https://doi.org/10.1089/cpt.2004.2.188
Enhanced Hypothermic Storage of Neonatal Cardiomyocytes
Cell Preservation Technology / Mar 01, 2005
Snyder, K. K., Baust, J. M., Van Buskirk, R. G., & Baust, J. G. (2005). Enhanced Hypothermic Storage of Neonatal Cardiomyocytes. Cell Preservation Technology, 3(1), 61–74. https://doi.org/10.1089/cpt.2005.3.61
Involvement of the Cysteine Protease Calpain Family in Cell Death After Cryopreservation
Cell Preservation Technology / Mar 01, 2006
Robilotto, A. T., Baust, J. M., Buskirk, R. V., & Baust, J. G. (2006). Involvement of the Cysteine Protease Calpain Family in Cell Death After Cryopreservation. Cell Preservation Technology, 4(1), 17–30. https://doi.org/10.1089/cpt.2006.4.17
Cardiomyocyte Responses to Thermal Excursions: Implications for Electrophysiological Cardiac Mapping
Cell Preservation Technology / Jun 01, 2007
Snyder, K. K., Baust, J. M., Van Buskirk, R. G., & Baust, J. G. (2007). Cardiomyocyte Responses to Thermal Excursions: Implications for Electrophysiological Cardiac Mapping. Cell Preservation Technology, 5(2), 116–128. https://doi.org/10.1089/cpt.2007.9995
Activation of Mitochondrial-Associated Apoptosis Contributes to Cryopreservation Failure
Cell Preservation Technology / Sep 01, 2007
Baust, J. M., Vogel, M. J., Snyder, K. K., Van Buskirk, R. G., & Baust, J. G. (2007). Activation of Mitochondrial-Associated Apoptosis Contributes to Cryopreservation Failure. Cell Preservation Technology, 5(3), 155–164. https://doi.org/10.1089/cpt.2007.9990
Preliminary Report: Evaluation of Storage Conditions and Cryococktails during Peripheral Blood Mononuclear Cell Cryopreservation
Cell Preservation Technology / Dec 01, 2007
Cosentino, L. M., Corwin, W., Baust, J. M., Diaz-Mayoral, N., Cooley, H., Shao, W., van Buskirk, R., & Baust, J. G. (2007). Preliminary Report: Evaluation of Storage Conditions and Cryococktails during Peripheral Blood Mononuclear Cell Cryopreservation. Cell Preservation Technology, 5(4), 189–204. https://doi.org/10.1089/cpt.2007.9987
Changing Paradigms in Biopreservation
Biopreservation and Biobanking / Mar 01, 2009
Baust, J. M., Snyder, K. K., VanBuskirk, R. G., & Baust, J. G. (2009). Changing Paradigms in Biopreservation. Biopreservation and Biobanking, 7(1), 3–12. https://doi.org/10.1089/bio.2009.0701.jmb
In VitroAssessment of Apoptosis and Necrosis Following Cold Storage in a Human Airway Cell Model
Biopreservation and Biobanking / Mar 01, 2009
Corwin, W. L., Baust, J. M., VanBuskirk, R. G., & Baust, J. G. (2009). In VitroAssessment of Apoptosis and Necrosis Following Cold Storage in a Human Airway Cell Model. Biopreservation and Biobanking, 7(1), 19–27. https://doi.org/10.1089/bio.2009.0002
How Much Will the Biobanking Industry Come to Rely on Private Companies?
Biopreservation and Biobanking / Dec 01, 2010
Clark, B. J., Baust, J. M., & Stacey, G. (2010). How Much Will the Biobanking Industry Come to Rely on Private Companies? Biopreservation and Biobanking, 8(4), 179–180. https://doi.org/10.1089/bio.2010.8415
Implications of Differential Stress Response Activation Following Non-Frozen Hepatocellular Storage
Biopreservation and Biobanking / Feb 01, 2013
Corwin, W. L., Baust, J. M., Baust, J. G., & Van Buskirk, R. G. (2013). Implications of Differential Stress Response Activation Following Non-Frozen Hepatocellular Storage. Biopreservation and Biobanking, 11(1), 33–44. https://doi.org/10.1089/bio.2012.0045
Integrating Molecular Control to Improve Cryopreservation Outcome
Biopreservation and Biobanking / Apr 01, 2017
Baust, J. G., Snyder, K. K., Van Buskirk, R., & Baust, J. M. (2017). Integrating Molecular Control to Improve Cryopreservation Outcome. Biopreservation and Biobanking, 15(2), 134–141. https://doi.org/10.1089/bio.2016.0119
Best practices in cell culture: an overview
In Vitro Cellular & Developmental Biology - Animal / Aug 14, 2017
Baust, J. M., Buehring, G. C., Campbell, L., Elmore, E., Harbell, J. W., Nims, R. W., Price, P., Reid, Y. A., & Simione, F. (2017). Best practices in cell culture: an overview. In Vitro Cellular & Developmental Biology - Animal, 53(8), 669–672. https://doi.org/10.1007/s11626-017-0177-7
Best practices for cryopreserving, thawing, recovering, and assessing cells
In Vitro Cellular & Developmental Biology - Animal / Nov 02, 2017
Baust, J. M., Campbell, L. H., & Harbell, J. W. (2017). Best practices for cryopreserving, thawing, recovering, and assessing cells. In Vitro Cellular & Developmental Biology - Animal, 53(10), 855–871. https://doi.org/10.1007/s11626-017-0201-y
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THANGASAMY SAMINATHAN
I have mix of expertise in Molecular Biology, Mapping and Functional Genomics, and Groundwater Remediation
Education
Academia Sinica
PhD Biotechnology, Taiwan International Graduate Program / January, 2011
Tamil Nadu Agricultural University
MSc Agriculture (Plant Breeding and Genetics), Center for Plant Breeding and Genetics / August, 2000
Tamil Nadu Agricultural University
BSc Agriculture, Anbil Dharmalingam Agricultural College and Research Institute / November, 1996
Experience
West Virginia Department of Environmental Protection
Environmental Resource Analyst / February, 2018 — Present
West Virginia State University
Associate Adjunct Faculty / May, 2013 — Present
Academia Sinica
Postdoctoral Research Fellow / February, 2011 — April, 2013
Most Relevant Research Expertise
Other Research Expertise (10)
About
Most Relevant Publications (1+)
29 total publications
Rice LGD1 containing RNA binding activity affects growth and development through alternative promoters
The Plant Journal / May 25, 2012
Thangasamy, S., Chen, P., Lai, M., Chen, J., & Jauh, G. (2012). Rice LGD1 containing RNA binding activity affects growth and development through alternative promoters. The Plant Journal, 71(2), 288–302. Portico. https://doi.org/10.1111/j.1365-313x.2012.04989.x
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Dr. David Siderovski, Ph.D.
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Education
University of Toronto
Ph.D., Medical Biophysics / November, 1997
Experience
University of North Carolina at Chapel Hill
Professor / January, 1999 — June, 2012
West Virginia University School of Medicine
E.J. Van Liere Endowed Medicine Professor and Chairman / July, 2012 — February, 2020
Chair of the Dept. of Physiology and Pharmacology
University of North Texas Health Science Center
Professor & Chair / March, 2020 — Present
Most Relevant Research Expertise
Other Research Expertise (25)
About
Most Relevant Publications (27+)
94 total publications
G-protein signaling: back to the future
Cellular and Molecular Life Sciences / Mar 01, 2005
McCudden, C. R., Hains, M. D., Kimple, R. J., Siderovski, D. P., & Willard, F. S. (2005). G-protein signaling: back to the future. Cellular and Molecular Life Sciences, 62(5), 551–577. https://doi.org/10.1007/s00018-004-4462-3
The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
International Journal of Biological Sciences / Jan 01, 2005
Siderovski, D. P., & Willard, F. S. (2005). The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits. International Journal of Biological Sciences, 51–66. https://doi.org/10.7150/ijbs.1.51
Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism
Nature Cell Biology / Jul 22, 2002
Lambert, J. M., Lambert, Q. T., Reuther, G. W., Malliri, A., Siderovski, D. P., Sondek, J., Collard, J. G., & Der, C. J. (2002). Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. Nature Cell Biology, 4(8), 621–625. https://doi.org/10.1038/ncb833
RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity
Journal of Biological Chemistry / Aug 01, 2001
Kimple, R. J., De Vries, L., Tronchère, H., Behe, C. I., Morris, R. A., Farquhar, M. G., & Siderovski, D. P. (2001). RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity. Journal of Biological Chemistry, 276(31), 29275–29281. https://doi.org/10.1074/jbc.m103208200
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
Journal of Biological Chemistry / Jul 01, 1998
Snow, B. E., Hall, R. A., Krumins, A. M., Brothers, G. M., Bouchard, D., Brothers, C. A., Chung, S., Mangion, J., Gilman, A. G., Lefkowitz, R. J., & Siderovski, D. P. (1998). GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain. Journal of Biological Chemistry, 273(28), 17749–17755. https://doi.org/10.1074/jbc.273.28.17749
LGN regulates mitotic spindle orientation during epithelial morphogenesis
Journal of Cell Biology / Apr 12, 2010
Zheng, Z., Zhu, H., Wan, Q., Liu, J., Xiao, Z., Siderovski, D. P., & Du, Q. (2010). LGN regulates mitotic spindle orientation during epithelial morphogenesis. Journal of Cell Biology, 189(2), 275–288. https://doi.org/10.1083/jcb.200910021
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
DNA and Cell Biology / Feb 01, 1994
SIDEROVSKI, D. P., HEXIMER, S. P., & FORSDYKE, D. R. (1994). A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells. DNA and Cell Biology, 13(2), 125–147. https://doi.org/10.1089/dna.1994.13.125
Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits
Journal of Biological Chemistry / Dec 01, 2001
Wing, M. R., Houston, D., Kelley, G. G., Der, C. J., Siderovski, D. P., & Harden, T. K. (2001). Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits. Journal of Biological Chemistry, 276(51), 48257–48261. https://doi.org/10.1074/jbc.c100574200
Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins
Nature Cell Biology / Oct 16, 2005
Wang, H., Ng, K. H., Qian, H., Siderovski, D. P., Chia, W., & Yu, F. (2005). Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins. Nature Cell Biology, 7(11), 1091–1098. https://doi.org/10.1038/ncb1317
Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells
Journal of Biological Chemistry / Jul 01, 2002
Wang, Q., Liu, M., Mullah, B., Siderovski, D. P., & Neubig, R. R. (2002). Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells. Journal of Biological Chemistry, 277(28), 24949–24958. https://doi.org/10.1074/jbc.m203802200
PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation
Journal of Biological Chemistry / Jan 01, 2010
Nakamura, K., Kimple, A. J., Siderovski, D. P., & Johnson, G. L. (2010). PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation. Journal of Biological Chemistry, 285(3), 2077–2089. https://doi.org/10.1074/jbc.m109.065102
Molecular Cloning and Expression Analysis of RatRgs12andRgs14
Biochemical and Biophysical Research Communications / Apr 01, 1997
Snow, B. E., Antonio, L., Suggs, S., Gutstein, H. B., & Siderovski, D. P. (1997). Molecular Cloning and Expression Analysis of RatRgs12andRgs14. Biochemical and Biophysical Research Communications, 233(3), 770–777. https://doi.org/10.1006/bbrc.1997.6537
Clathrin Adaptor AP2 Regulates Thrombin Receptor Constitutive Internalization and Endothelial Cell Resensitization
Molecular and Cellular Biology / Apr 01, 2006
Paing, M. M., Johnston, C. A., Siderovski, D. P., & Trejo, J. (2006). Clathrin Adaptor AP2 Regulates Thrombin Receptor Constitutive Internalization and Endothelial Cell Resensitization. Molecular and Cellular Biology, 26(8), 3231–3242. https://doi.org/10.1128/mcb.26.8.3231-3242.2006
Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins
Journal of Biological Chemistry / Dec 01, 2001
Snyder, J. T., Rossman, K. L., Baumeister, M. A., Pruitt, W. M., Siderovski, D. P., Der, C. J., Lemmon, M. A., & Sondek, J. (2001). Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins. Journal of Biological Chemistry, 276(49), 45868–45875. https://doi.org/10.1074/jbc.m106731200
Telomerase-Associated Protein TEP1 Is Not Essential for Telomerase Activity or Telomere Length Maintenance In Vivo
Molecular and Cellular Biology / Nov 01, 2000
Liu, Y., Snow, B. E., Hande, M. P., Baerlocher, G., Kickhoefer, V. A., Yeung, D., Wakeham, A., Itie, A., Siderovski, D. P., Lansdorp, P. M., Robinson, M. O., & Harrington, L. (2000). Telomerase-Associated Protein TEP1 Is Not Essential for Telomerase Activity or Telomere Length Maintenance In Vivo. Molecular and Cellular Biology, 20(21), 8178–8184. https://doi.org/10.1128/mcb.20.21.8178-8184.2000
Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq
Journal of Biological Chemistry / Jun 01, 2001
Evanko, D. S., Thiyagarajan, M. M., Siderovski, D. P., & Wedegaertner, P. B. (2001). Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq. Journal of Biological Chemistry, 276(26), 23945–23953. https://doi.org/10.1074/jbc.m101154200
A Set of Human Putative Lymphocyte G0/G1Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes
DNA and Cell Biology / Oct 01, 1990
SIDEROVSKI, D. P., BLUM, S., FORSDYKE, R. E., & FORSDYKE, D. R. (1990). A Set of Human Putative Lymphocyte G0/G1Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes. DNA and Cell Biology, 9(8), 579–587. https://doi.org/10.1089/dna.1990.9.579
Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)
Journal of Biological Chemistry / Jul 01, 2009
Kimple, A. J., Soundararajan, M., Hutsell, S. Q., Roos, A. K., Urban, D. J., Setola, V., Temple, B. R. S., Roth, B. L., Knapp, S., Willard, F. S., & Siderovski, D. P. (2009). Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2). Journal of Biological Chemistry, 284(29), 19402–19411. https://doi.org/10.1074/jbc.m109.024711
Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif
Biochemical Journal / Mar 15, 2004
KIMPLE, R. J., WILLARD, F. S., HAINS, M. D., JONES, M. B., NWEKE, G. K., & SIDEROVSKI, D. P. (2004). Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. Biochemical Journal, 378(3), 801–808. https://doi.org/10.1042/bj20031686
Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane
Molecular Biology of the Cell / Sep 01, 2006
Dho, S. E., Trejo, J., Siderovski, D. P., & McGlade, C. J. (2006). Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane. Molecular Biology of the Cell, 17(9), 4142–4155. https://doi.org/10.1091/mbc.e06-02-0097
Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13
Journal of Biological Chemistry / Dec 01, 2001
Blake, B. L., Wing, M. R., Zhou, J. Y., Lei, Q., Hillmann, J. R., Behe, C. I., Morris, R. A., Harden, T. K., Bayliss, D. A., Miller, R. J., & Siderovski, D. P. (2001). Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13. Journal of Biological Chemistry, 276(52), 49267–49274. https://doi.org/10.1074/jbc.m106565200
A direct fluorescence-based assay for RGS domain GTPase accelerating activity
Analytical Biochemistry / May 01, 2005
Willard, F. S., Kimple, A. J., Johnston, C. A., & Siderovski, D. P. (2005). A direct fluorescence-based assay for RGS domain GTPase accelerating activity. Analytical Biochemistry, 340(2), 341–351. https://doi.org/10.1016/j.ab.2005.02.015
A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding
Journal of Biological Chemistry / Dec 01, 2008
Willard, F. S., Zheng, Z., Guo, J., Digby, G. J., Kimple, A. J., Conley, J. M., Johnston, C. A., Bosch, D., Willard, M. D., Watts, V. J., Lambert, N. A., Ikeda, S. R., Du, Q., & Siderovski, D. P. (2008). A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding. Journal of Biological Chemistry, 283(52), 36698–36710. https://doi.org/10.1074/jbc.m804936200
Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research / Sep 01, 2005
McCudden, C. R., Willard, F. S., Kimple, R. J., Johnston, C. A., Hains, M. D., Jones, M. B., & Siderovski, D. P. (2005). Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1745(2), 254–264. https://doi.org/10.1016/j.bbamcr.2005.05.002
The effect of RGS12 on PDGFβ receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells
Cellular Signalling / Jul 01, 2006
Sambi, B. S., Hains, M. D., Waters, C. M., Connell, M. C., Willard, F. S., Kimple, A. J., Pyne, S., Siderovski, D. P., & Pyne, N. J. (2006). The effect of RGS12 on PDGFβ receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells. Cellular Signalling, 18(7), 971–981. https://doi.org/10.1016/j.cellsig.2005.08.003
Covalent immobilization of histidine-tagged proteins for surface plasmon resonance
Analytical Biochemistry / Jun 01, 2006
Willard, F. S., & Siderovski, D. P. (2006). Covalent immobilization of histidine-tagged proteins for surface plasmon resonance. Analytical Biochemistry, 353(1), 147–149. https://doi.org/10.1016/j.ab.2006.02.004
Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia
Journal of Biological Chemistry / Dec 01, 2012
Cohen, S. P., Buckley, B. K., Kosloff, M., Garland, A. L., Bosch, D. E., Cheng, G., Radhakrishna, H., Brown, M. D., Willard, F. S., Arshavsky, V. Y., Tarran, R., Siderovski, D. P., & Kimple, A. J. (2012). Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia. Journal of Biological Chemistry, 287(50), 41706–41719. https://doi.org/10.1074/jbc.m112.423806
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Martin Tsui
University of California, San Francisco
Education
Florida State University
Ph.D., Molecular Biophysics / July, 2017
University of California, San Diego
B.S., Chemistry / June, 2012
Experience
Stealth
Founder & CEO / January, 2023 — Present
Genome engineering
Amazon
Senior Scientist / December, 2021 — February, 2023
Molecular Diagnostics
Van Andel Institute
Postdoctoral Fellow / September, 2020 — April, 2021
Cryo-EM of membrane proteins
Most Relevant Research Expertise
Other Research Expertise (15)
About
Most Relevant Publications (2+)
16 total publications
Structure Principles of CRISPR-Cas Surveillance and Effector Complexes
Annual Review of Biophysics / Jun 22, 2015
Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
Nature Chemical Biology / Oct 20, 2020
Bracken, C. J., Lim, S. A., Solomon, P., Rettko, N. J., Nguyen, D. P., Zha, B. S., Schaefer, K., Byrnes, J. R., Zhou, J., Lui, I., Liu, J., Pance, K., Azumaya, C. M., Braxton, J. R., Brilot, A. F., Gupta, M., Li, F., Lopez, K. E., … Melo, A. (2020). Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2. Nature Chemical Biology, 17(1), 113–121. https://doi.org/10.1038/s41589-020-00679-1
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Odion Ikhimiukor
Postdoctoral Research Scientist at University at Albany, State University of New York
Education
University of Ibadan
PhD Microbiology, Bacterial genomics, Bioinformatics, Microbiology
University of Ibadan
Master of Science (M. Sc.), Environmental Microbiology / April, 2015
University of Abuja
Bachelor of Science (B.Sc.), Microbiology / March, 2011
Experience
University at Albany, State University of New York
Postdoctoral Associate
National Institute for Pharmaceutical Research and Development
FCT Emergency Services, Asokoro District Hospital
Most Relevant Research Expertise
Other Research Expertise (23)
About
Most Relevant Publications (2+)
27 total publications
A bottom-up view of antimicrobial resistance transmission in developing countries
Nature Microbiology / May 30, 2022
Ikhimiukor, O. O., Odih, E. E., Donado-Godoy, P., & Okeke, I. N. (2022). A bottom-up view of antimicrobial resistance transmission in developing countries. Nature Microbiology, 7(6), 757–765. https://doi.org/10.1038/s41564-022-01124-w
Phylogenetic lineages and antimicrobial resistance determinants of clinical Klebsiella oxytoca spanning local to global scales
Microbiology Spectrum / Oct 17, 2023
Ikhimiukor, O. O., Souza, S. S. R., Akintayo, I. J., Marcovici, M. M., Workman, A., Martin, I. W., & Andam, C. P. (2023). Phylogenetic lineages and antimicrobial resistance determinants of clinical Klebsiella oxytoca spanning local to global scales. Microbiology Spectrum, 11(5). https://doi.org/10.1128/spectrum.00549-23
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Example Cell Biology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Cell Biology?
Drug Discovery and Development
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Cancer Research and Treatment
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Environmental Monitoring and Remediation
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