Work with thought leaders and academic experts in Pharmacology

Companies can greatly benefit from working with experts in the field of Pharmacology. These researchers possess in-depth knowledge of drug interactions, mechanisms of action, and therapeutic applications. By collaborating with them, companies can enhance their research and development efforts, gain insights into new drug targets, optimize drug formulations, and improve clinical trial design. Pharmacology experts can also provide valuable guidance in regulatory affairs, ensuring compliance with safety and efficacy standards. Additionally, their expertise can help companies identify potential drug-drug interactions and adverse effects, leading to safer and more effective medications. Overall, partnering with Pharmacology thought leaders can accelerate innovation, improve product quality, and drive business growth.

Researchers on NotedSource with backgrounds in Pharmacology include Aimee Eggler, Gwendolyn Thomas, Ph.D., CSCS, USAW-L1, Denver Ncube, Ph.D., Dr. David Siderovski, Ph.D., Regan Hamel, Dushani L. Palliyaguru, Ph.D., Dr. Everson A Nunes, Ph.D., Elvira Forte, Susan Song, MD/PhD, Katie Barr, and Lindsay Webb, PhD.

Aimee Eggler

Villanova, Pennsylvania, United States of America
20 Years Experience
Professor of Chemistry and Biochemistry at Villanova University
Education

University of California, Santa Cruz

BS, Chemistry / May, 1996

Santa Cruz, California, United States of America

University of Wisconsin–Madison

Ph.D., Biochemistry / May, 2002

Madison, Wisconsin, United States of America
Experience

Villanova University

Associate Professor of Chemistry / 2019 — Present

Villanova University

Assistant Professor / 2012 — 2019

Purdue University

Research Assistant Professor / 2010 — 2012

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (18)
Biochemistry
Physiology (medical)
Toxicology
Organic Chemistry
Clinical Biochemistry
And 13 more
About
Dr. Eggler has 20 years of experience in the field of redox biology, with a focus on the Nrf2 transcription factor, a master regulator of antioxidant, detoxification and anti-inflammatory genes. She is also an award-winning educator and the recipient of the Villanova University Junior Faculty Excellence in Teaching award. Her interests in education include innovation in teaching metabolism from a logic-based perspective.
Most Relevant Publications (1+)

25 total publications

Solving the Problem of Assessing Synergy and Antagonism for Non-Traditional Dosing Curve Compounds Using the DE/ZI Method: Application to Nrf2 Activators

Frontiers in Pharmacology / Jun 07, 2021

Repash, E. M., Pensabene, K. M., Palenchar, P. M., & Eggler, A. L. (2021). Solving the Problem of Assessing Synergy and Antagonism for Non-Traditional Dosing Curve Compounds Using the DE/ZI Method: Application to Nrf2 Activators. Frontiers in Pharmacology, 12. https://doi.org/10.3389/fphar.2021.686201

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Gwendolyn Thomas, Ph.D., CSCS, USAW-L1

Philadelphia, Pennsylvania, United States of America
17 Years Experience
Resistance Exercise Physiologist/Performance Enhancement/Optimizing RE Prescription
Education

University of Connecticut

Ph.D., Kinesiology (Exercise Endocrinology, Exercise Physiology, Resistance Exercise) / May, 2010

Storrs, Connecticut, United States of America

University of Connecticut

M.A., Strength and Conditioning / May, 2007

Storrs, Connecticut, United States of America
Experience

Penn State University

Assistant Research Professor / September, 2019 — August, 2023

Principal Investigator of the Exercise Prescription Lab. The lab (PI: Thomas) conducts interdisciplinary and translational research on chronic diseases, publishing in peer-reviewed journals. Transform population health outcomes through data, analytics, and actionable insights. Chair the regulatory review board, overseeing IRB Administration, running meetings, and approving research protocols. Expertise in institutional, FDA, and Federal regulatory work.

Penn State Integrative Physiology

Faculty Member / September, 2019 — Present

Faculty Member In Integrative Physiology

Syracuse University

Assistant Professor / August, 2016 — August, 2019

Independent Principal Investigator: Assumed responsibility for all research studies conducted in my lab, including but not limited to oversight and training of research assistants (25), training of research assistants (30), and generating independent, high quality, reproducible results. Responsible for the management and integrity of design, conduct and reporting of the research project and for managing, monitoring and ensuring the integrity of collaborative relationships. Curriculum Committee Chair:Led Curriculum Committee and Departmental Leadership to develop Master’s Degree in Strength and Conditioning through certifying agency, the National Strength and Conditioning Association (NSCA).

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (30)
resistance exercise
obesity
breast cancer
chronic disease
inflammation
And 25 more
About
My work has focused on how we can use data to support decisions to individualize monitoring to optimize human performance.  My work has demonstrated that a one size fits all approach is not the way to optimize performance in any setting.  My monitoring approach is one that utilizes a network physiology paradigm, which focuses on nonlinear dynamic interactions. In my athlete monitoring I focus on leveraging EMA and wearables; biological sampling and resistance exercise and conditioning prescribed to elicit a specific biological response.    Additionally, as a practitioner it is important to understand the limitations of athlete monitoring, which is another area research and practice has focused.  This is an important skillset that is currently being utilized by the in a project entitled “Integrating mHealth and Physical Function to Develop a Predictors of Injury and Optimal Performance Model in Special Military Operators “with the Rangers in the 3/75 Ranger Battalion.  This approach is one that quantifies factors such as dosage variables of training and lifestyle factors (sleep, nutrition, life stress).  Using this data, we are working on individualizing acute training sessions to optimize readiness and performance enhancement.   During my time at Syracuse University, I was the professor of record to teach the NSCA CSCS preparation course and lead the strength and conditioning program.  We were developing a master’s in exercise science and I was in the process of working on certification with the NSCA.  We also worked closely with athletics to secure strength and conditioning assistantships to allow for student funding.  I am currently on several NSCA committees, which include the Education and Women’s Committee (next certification cycle).    I am particularly adept at all phases of the athletic performance enhancement and these experiences have given me expertise in evidence based program design, linear and non-linear periodization, exercise endocrinology, resistance exercise physiology and acute and chronic training readiness and non-training parameters
Most Relevant Publications (1+)

51 total publications

Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women

Steroids / Nov 01, 2009

Vingren, J. L., Kraemer, W. J., Hatfield, D. L., Volek, J. S., Ratamess, N. A., Anderson, J. M., Häkkinen, K., Ahtiainen, J., Fragala, M. S., & Thomas, G. A. (2009). Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Steroids, 74(13–14), 1033–1039. https://doi.org/10.1016/j.steroids.2009.08.002

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Denver Ncube, Ph.D.

Morrisville, North Carolina, United States of America
8 Years Experience
Computational biologist/bioinformatician with a passion for extracting meaningful insight from complex biological data.
Education

University of Zimbabwe Faculty of Veterinary Science

Master of Science in Anatomy , Department of Veterinary Science / July, 2012

Harare

University of Zimbabwe College of Health Sciences

BSc Honours(Intercalated) in Human Anatomy, Anatomy / February, 2009

Harare

University of Oregon

Ph.D., Biology / August, 2021

Eugene, Oregon, United States of America
Experience

University of Oregon

Neuroscientist / June, 2021 — Present

University of Oregon

Graduate Student / August, 2016 — June, 2021

Flagship Biosciences

Computational Biologist / March, 2023 — Present

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (4)
Neuroscience
Cell Biology
Anatomy
Toxicology
About
With over 8 years of experience in neuroscience and bioinformatics, I am a computational biologist who is passionate about applying data science and machine learning to unravel the molecular and cellular mechanisms of complex diseases, such as cancer and neurodegenerative disorders.
Most Relevant Publications (1+)

6 total publications

Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats

Journal of Toxicology / Jan 01, 2017

Khoza, S., Moyo, I., & Ncube, D. (2017). Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats. Journal of Toxicology, 2017, 1–9. https://doi.org/10.1155/2017/6746989

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Dr. David Siderovski, Ph.D.

Fort Worth
25 Years Experience
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Education

University of Toronto

Ph.D., Medical Biophysics / November, 1997

Toronto, Ontario, Canada
Experience

University of North Carolina at Chapel Hill

Professor / January, 1999 — June, 2012

West Virginia University School of Medicine

E.J. Van Liere Endowed Medicine Professor and Chairman / July, 2012 — February, 2020

Chair of the Dept. of Physiology and Pharmacology

University of North Texas Health Science Center

Professor & Chair / March, 2020 — Present

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (25)
Regulator of G protein Signaling (RGS) proteins
Molecular Biology
Cellular and Molecular Neuroscience
Molecular Medicine
Cell Biology
And 20 more
About
Dr. David Siderovski is a renowned scientist and academic, with a career spanning over two decades. He received his Ph.D. in Medical Biophysics from the University of Toronto in 1997, where he specialized in signal transduction and cellular signaling pathways. After completing his doctorate, Dr. Siderovski held various faculty positions at prestigious universities, including the University of North Carolina at Chapel Hill, West Virginia University School of Medicine, and the University of North Texas Health Science Center. At these institutions, Dr. Siderovski has made significant contributions to the field of pharmacology through his research on G protein-coupled receptors (GPCRs) and RGS proteins, which are key regulators of GPCR cellular signaling. His work has helped to advance the understanding of RGS proteins and their roles in various diseases, including cancer, cardiovascular disorders, and neurological disorders. In addition to his research, Dr. Siderovski is also a dedicated educator and mentor. He has taught and mentored numerous undergraduate, graduate, and medical students, and has served as a mentor for postdoctoral fellows and junior faculty members. He is known for his passion and enthusiasm for science and his ability to inspire and guide the next generation of scientists. Dr. Siderovski has received numerous awards and honors for his contributions to the scientific community. He was the recipient of the Abel Award in 2004 from the American Society of Pharmacology & Experimental Therapeutics for his pioneering discoveries of the RGS proteins and the GoLoco motif. He has also served on editorial boards of several scientific journals (including a decade at *J.Biol.Chem.*) and has been a member of various scientific committees, NIH study section panels, and pharma/biotech advisory boards, including for Inspire, Wyeth, and BellBrook Labs. Overall, Dr. David Siderovski is a highly accomplished and respected scientist and educator, whose research has had a significant impact on the field of pharmacology. His dedication and passion for science continue to inspire and influence the next generation of researchers in this field.
Most Relevant Publications (7+)

94 total publications

G-protein signaling: back to the future

Cellular and Molecular Life Sciences / Mar 01, 2005

McCudden, C. R., Hains, M. D., Kimple, R. J., Siderovski, D. P., & Willard, F. S. (2005). G-protein signaling: back to the future. Cellular and Molecular Life Sciences, 62(5), 551–577. https://doi.org/10.1007/s00018-004-4462-3

Regulators of G-Protein signalling as new central nervous system drug targets

Nature Reviews Drug Discovery / Mar 01, 2002

Neubig, R. R., & Siderovski, D. P. (2002). Regulators of G-Protein signalling as new central nervous system drug targets. Nature Reviews Drug Discovery, 1(3), 187–197. https://doi.org/10.1038/nrd747

Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets

Pharmacological Reviews / Jul 07, 2011

Kimple, A. J., Bosch, D. E., Giguère, P. M., & Siderovski, D. P. (2011). Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets. Pharmacological Reviews, 63(3), 728–749. https://doi.org/10.1124/pr.110.003038

Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights

Molecular Pharmacology / Apr 12, 2007

Johnston, C. A., & Siderovski, D. P. (2007). Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights. Molecular Pharmacology, 72(2), 219–230. https://doi.org/10.1124/mol.107.034348

Chronic Olanzapine Treatment Causes Differential Expression of Genes in Frontal Cortex of Rats as Revealed by DNA Microarray Technique

Neuropsychopharmacology / Jan 11, 2006

Fatemi, S. H., Reutiman, T. J., Folsom, T. D., Bell, C., Nos, L., Fried, P., Pearce, D. A., Singh, S., Siderovski, D. P., Willard, F. S., & Fukuda, M. (2006). Chronic Olanzapine Treatment Causes Differential Expression of Genes in Frontal Cortex of Rats as Revealed by DNA Microarray Technique. Neuropsychopharmacology, 31(9), 1888–1899. https://doi.org/10.1038/sj.npp.1301002

Gα12/13- and Rho-Dependent Activation of Phospholipase C-ϵ by Lysophosphatidic Acid and Thrombin Receptors

Molecular Pharmacology / Mar 22, 2006

Hains, M. D., Wing, M. R., Maddileti, S., Siderovski, D. P., & Harden, T. K. (2006). Gα12/13- and Rho-Dependent Activation of Phospholipase C-ϵ by Lysophosphatidic Acid and Thrombin Receptors. Molecular Pharmacology, 69(6), 2068–2075. https://doi.org/10.1124/mol.105.017921

Induction of Regulator of G-Protein Signaling 2 Expression by Long-Acting β2-Adrenoceptor Agonists and Glucocorticoids in Human Airway Epithelial Cells

Journal of Pharmacology and Experimental Therapeutics / Oct 25, 2013

Holden, N. S., George, T., Rider, C. F., Chandrasekhar, A., Shah, S., Kaur, M., Johnson, M., Siderovski, D. P., Leigh, R., Giembycz, M. A., & Newton, R. (2013). Induction of Regulator of G-Protein Signaling 2 Expression by Long-Acting β2-Adrenoceptor Agonists and Glucocorticoids in Human Airway Epithelial Cells. Journal of Pharmacology and Experimental Therapeutics, 348(1), 12–24. https://doi.org/10.1124/jpet.113.204586

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Regan Hamel

Cambridge
6 Years Experience
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
Education

University of Cambridge

PhD, Clinical Neurosciences / September, 2021

Cambridge

University of Cambridge

MPhil, Clinical Neurosciences / September, 2018

Cambridge

McGill University

Bachelor of Science, Neurosciences / June, 2017

Montreal
Experience

Mogrify Ltd

Bioinformatics scientist / August, 2021 — June, 2023

Senior Bioinformatics Scientist / July, 2023 — Present

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (12)
single cell biology
transcriptomics
Cellular and Molecular Neuroscience
Cell Biology
Developmental Biology
And 7 more
About
Regan Hamel has an MPhil and PhD in Clinical Neurosciences from University of Cambridge. She also has a Bachelor of Science in Neurosciences from McGill University. Her PhD with Stefano Pluchino and John Marioni focused on single cell transcriptomics in the context of neuroinflammation. Since 2021 she has worked as a Bioinformatics scientist at Mogrify Ltd, applying a multitude of computational biology techniques (including single cell omics, bulk RNAseq, and predictive modelling) in the context of cell reprogramming
Most Relevant Publications (1+)

12 total publications

Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice

Molecular Therapy / Dec 01, 2020

Braga, A., Bandiera, S., Verheyen, J., Hamel, R., Rutigliani, C., Edenhofer, F., Smith, J. A., & Pluchino, S. (2020). Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Molecular Therapy, 28(12), 2677–2690. https://doi.org/10.1016/j.ymthe.2020.08.001

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Dushani L. Palliyaguru, Ph.D.

Baltimore, MD, Maryland, United States of America
16 Years Experience
Toxicologist | Aging, Nutrition and Metabolism Research Scientist | Systems Biologist
Education

University of Pittsburgh

Ph.D., Environmental and Occupational Health (Toxicology) / May, 2016

Pittsburgh, Pennsylvania, United States of America

Clark University

B.A., Biochemistry and Molecular Biology, Mathematics / May, 2009

Worcester, Massachusetts, United States of America
Experience

National Institute on Aging Intramural Research Program, Translational Gerontology Branch

IRTA Postdoctoral Fellow, K99/R00 Grant Recipient / September, 2018 — Present

-Leading, managing and coordinating large population longitudinal studies within US Federal Government and Industry partnerships - Successfully writing, submitting, and managing grants and manuscripts to ensure continuity of research initiatives -Hiring, mentoring, and supervising research fellows and technicians -Applying epidemiological, machine learning and data science methods to multi-omics data to characterize biomarkers of aging and aging-related diseases -Testing nutritional and pharmacological compounds for lifespan extension, and prevention of chronic diseases (eg. Alzheimer’s)

University of Pittsburgh, Department of Pharmacology and Chemical Biology

Postdoctoral Fellow / May, 2016 — September, 2018

Identified a novel urinary biomarker of cruciferous vegetable intake in cancer prevention clinical trials using liquid chromatography mass spectrometry -Led and managed project that showed broccoli-derived sulforaphane prevented breast cancer through altering gene expression and lipidomics profiles

Healthcare Ready

Health Policy Fellow / January, 2017 — January, 2018

-Synthesized data, mined literature and wrote Toolkits/ Issue Brief on “Pharmacy and Emergency Preparedness: A Landscape Analysis”

Research Expertise (17)
Nutrition
aging
Oncology
Hematology
Molecular Biology
And 12 more
About
·   Highly productive scientist with 13 years of multidisciplinary experience in toxicology, molecular nutrition, and aging/ disease biomarkers ·   Excellent communicator with proven record of advanced writing and presentation skills - manuscripts, conference presentations, and grants ·   Extensive experience in large study design, supervision and coordination, big data analysis, and management of junior scientists

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Dr. Everson A Nunes, Ph.D.

Hamilton, Ontario, Canada
19 Years Experience
Post-Doctoral Fellow at McMaster University | former Associate Professor - Physiological Sciences
Education

Universidade Federal do Paraná - Campus Centro Politécnico

PhD, Physiological Sciences / December, 2009

Curitiba

Universidade Federal do Paraná - Campus Centro Politécnico

BSc - Human Nutrition / December, 2007

Curitiba

Universidade Federal do Paraná - Campus Centro Politécnico

MSc, Physiological Sciences / March, 2005

Curitiba
Experience

McMaster University

Post Doctoral Fellow / September, 2019 — Present

Post-Doctoral Research Fellow / September, 2015 — August, 2016

Universidade Federal de Santa Catarina

Associate professor / October, 2013 — April, 2022

Assistant Professor / October, 2010 — September, 2013

Universidade Federal do Paraná

Post-Doctoral Fellow / December, 2009 — September, 2010

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (39)
skeletal muscle
nutrition
physical activity
obesity
cancer
And 34 more
About
Dr. Everson A Nunes is a highly accomplished researcher and educator in the field of physiological sciences. He received his Ph.D. in Cellular and Molecular Biology with a focus on Physiological Sciences from Universidade Federal do Paraná in 2009, after completing a BSc in Human Nutrition and an MSc in Physiological Sciences. He also holds a specialization in Exercise Physiology and a BSc in Biological Sciences from Universidade Federal do Paraná. Dr. Nunes has a strong background in research, having completed two post-doctoral fellowships at McMaster University and Universidade Federal do Paraná. He has also held positions as an associate professor and assistant professor at Universidade Federal de Santa Catarina. He has published numerous articles in peer-reviewed journals, and his research focuses on the effects of exercise and nutrition on physiological processes in the human body. In addition to his research, Dr. Nunes is also a dedicated educator. He has taught at various universities in Brazil, including Universidade Federal de Santa Catarina, Universidade Gama Filho, Faculdades Integradas Espírita, Pontificia Universidade Católica do Paraná, and Faculdade do Litoral Sul. He is known for his dynamic teaching style and his ability to engage students in complex physiological concepts. Dr. Nunes is a member of several professional organizations, including the American Society for Nutrition, the Canadian Society of Exercise Physiology, the Canadian Nutrition Society and the Brazilian Society of Physiology. He is also a regular speaker at national and international conferences, sharing his expertise and research findings with colleagues and students. Overall, Dr. Nunes is a highly qualified and experienced professional in physiological sciences, metabolism, cancer and nutrition. His dedication to research and education makes him a valuable asset to any institution.
Most Relevant Publications (2+)

97 total publications

Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats

Canadian Journal of Physiology and Pharmacology / Oct 01, 2014

dos Santos, C., Ferreira, F. B. D., Gonçalves-Neto, L. M., Taboga, S. R., Boschero, A. C., & Rafacho, A. (2014). Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats. Canadian Journal of Physiology and Pharmacology, 92(10), 867–878. https://doi.org/10.1139/cjpp-2014-0259

Implications of Palmitoleic Acid (Palmitoleate) On Glucose Homeostasis, Insulin Resistance and Diabetes

Current Drug Targets / Mar 30, 2017

Nunes, E., & Rafacho, A. (2017). Implications of Palmitoleic Acid (Palmitoleate) On Glucose Homeostasis, Insulin Resistance and Diabetes. Current Drug Targets, 18(6), 619–628. https://doi.org/10.2174/1389450117666151209120345

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Elvira Forte

New York, New York, United States of America
15 Years Experience
Scientific strategist • Senior Scientist • Senior Scientific Editor
Education

Sapienza University of Rome

PhD, Pasteurian Sciences / January, 2011

Rome

Sapienza University of Rome

Master, Medical, Molecular and Cellular Biotechnology / October, 2006

Rome

Sapienza University of Rome

Bachelor, Biotechnology / October, 2004

Rome
Experience

Springer Nature

Associate/Senior Editor / June, 2021 — February, 2024

Helped shape and launch a new journal, Nature Cardiovascular Research, which publishes exceptional advances in the fields of cardiac, vascular, and blood biology, covering fundamental, translational, clinical, and public health research. • Assessed the novelty and impact of manuscripts within all the topics covered by the journal and chaperoned the whole revision process until acceptance for over 40% of all the content published by the journal since its start, with optimal processing times and excellent feedback from the authors. • Interfaced with scientists around the World, provided scientific guidance on how to improve manuscripts, or recommended more appropriate journals to publish with. Commissioned Comments, Reviews, News and Views on current topics, and summarized novel scientific findings in meaningful snippets and Research Highlights. • Contributed to the training and supervision of 2 Associate Editors; covered the Chief Editor's functions when needed.

Research Fellow/Associate Research Scientist / January, 2017 — June, 2021

• Analyzed the dynamic cellular changes during the fibrotic repair post-myocardial infarction, using cutting-edge techniques such as single-cell RNAseq with 10xChromium. Learned how to perform myocardial infarction in mice and assess the cardiac function via echography; analyze scRNAseq data using the Seurat package on R studio. • Completed a project aimed to characterize similarities and differences among fibroblasts from different organs cultured in the same conditions. Through cytometric, transcriptomic analysis, functional assays, shRNA and CRISPR-Cas9-mediated in vitro gene knockdowns we showed that fibroblasts isolated from different organs retain the expression of key transcription factors reflecting their embryological origin. • Collaborated with other laboratories in the Institute to design new mice models that could possibly recapitulate the symptoms of COVID-19; to analyze the response of mice with diverse genetic backgrounds to stressors.

Post-doctoral fellow/ Co-joint lecturer / May, 2013 — November, 2016

Developed projects aimed at understanding the embryological origin and function of a population of putative progenitor cells, cardiac colony forming unit fibroblasts cCFU-F, identified 2 years before in the lab (PMID: 22136928). • Performed cell lineage tracing and designed in vitro and in vivo cellular assays to assess the functional and immunomodulatory properties of PDGFRa+ fibroblasts in homeostasis and post-myocardial infarction with or without treatment with the PDGF-AB ligands. The data, presented in 3 international conferences and included in a preprint manuscript, have supported the use of a short-term treatment with PDGF-AB in a preclinical model of acute myocardial infarction in pigs. • Co-supervised 2 Ph.D. students at University of New South Wales

Scientific Editor / March, 2024 — Present

Consultant freelancer position within a team of former journal editors and grants specialists • Helped scientists increase the impact of their science by providing advice, in-depth editing, and feedback on manuscripts.

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (26)
fibrosis
inflammation
cardiomyopathies
Physiology
Cardiology and Cardiovascular Medicine
And 21 more
About
Motivated and growth-driven biomedical scientist with over 15 years of experience in the cardiovascular field. Strong background in cell and molecular biology, data analysis, and interpretation. Seeking #newopportunities to deliver value as a Senior Scientist, Associate Principal Scientist, Scientific Liaison, or Scientific Consultant within a company that combines new technologies such as single-cell omics and AI for drug discovery and personalized medicine. <br> Throughout my career, I've used various in vivo and in vitro models to investigate the molecular and cellular mechanisms of fibrosis and inflammation in the heart, and how these mechanisms are affected in mice with different genetic backgrounds. My experience includes project management and mentoring. I completed three projects involving international collaborations, supervised two junior researchers, and taught cellular and molecular techniques to at least six professionals. As one of the launching editors and senior editor at Nature Cardiovascular Research, I oversaw the quality of the content published in the journal and the editorial process. I collaborated with authors, reviewers, and editors to ensure the highest standards of scientific rigor, relevance, and innovation. I also contributed to the journal's vision, strategy, and outreach, promoting the latest advances and discoveries in the cardiovascular and hematology fields. This experience has sharpened my analytical and communication skills and broadened my understanding of the field, covering a wide range of studies, from basic research to clinical, epidemiological, and public health research. My mission is to advance the knowledge and practice of cardiovascular medicine and to bridge the gap between research and clinical applications. Keywords: cardiovascular, #fibrosis, inflammation, cardioimmunology, RNA, single-cell biology, #transcriptomics, imaging, animal models, small animal surgery, and scientific writing.
Most Relevant Publications (1+)

63 total publications

New Perspectives to Repair a Broken Heart

Cardiovascular &amp; Hematological Agents in Medicinal Chemistry / Apr 01, 2009

Gaetani, R., Barile, L., Forte, E., Chimenti, I., Ionta, V., Di Consiglio, A., Miraldi, F., Frati, G., Messina, E., & Giacomello, A. (2009). New Perspectives to Repair a Broken Heart. Cardiovascular &amp; Hematological Agents in Medicinal Chemistry, 7(2), 91–107. https://doi.org/10.2174/187152509787847128

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Susan Song, MD/PhD

Pittsburgh, Pennsylvania, United States of America
9 Years Experience
Research Assistant Professor in Neuroscience at University of Pittsburgh
Education

Southern Medical University

MD/PhD, Neurology, Neuroscience / June, 2015

Guangzhou

University of Pittsburgh

Post-doc, Neuroscience / December, 2019

Pittsburgh, Pennsylvania, United States of America
Experience

University of Pittsburgh

Research Assistant Professor / January, 2022 — Present

Research Instructor / January, 2020 — December, 2021

Postdoctoral Scholar / October, 2015 — December, 2019

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (15)
microglia
white matter
neurodegenerative disease
Cellular and Molecular Neuroscience
Neurology
And 10 more
About
Susan Song, MD/PhD, is a highly accomplished neuroscientist, with extensive education and experience in the field. She received her MD/PhD in Neurology and Neuroscience from Southern Medical University in 2015, where she conducted groundbreaking research on the molecular mechanisms of neurodegenerative diseases. Following this, she completed a post-doctoral fellowship in Neuroscience at the University of Pittsburgh, where she continued to excel in her research and received numerous awards and grants for her work. Dr. Song's expertise lies in studying the underlying causes and potential treatments for various neurological diseases, such as ischemic stroke, traumatic brain injury, glioblastoma, Alzheimer's disease, and multiple sclerosis. She has a deep understanding of the brain and nervous system, and is constantly seeking new ways to unravel the complexities of these diseases. Dr. Song has held several prestigious positions throughout her career, including her current position as Research Assistant Professor at the University of Pittsburgh. She has published numerous articles in top scientific journals and presented her research at international conferences. Her findings have contributed greatly to the field of neurology and have the potential to improve the lives of millions of people suffering from neurological disorders. Overall, Dr. Song is a highly respected and accomplished physician-scientist who is making significant contributions to the field of neurology. With her extensive education, diverse experience, and unwavering dedication to her patients, she is a true leader in the field and a valuable asset to the medical community.

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Katie Barr

Warrington
8 Years Experience
Bioinformatician and developer with strong academic and commercial experience
Education

University of Leeds

Ph.D, Quantum Information / December, 2013

Leeds

University of Manchester

MSc, Mathematical logic and the theory of computation / December, 2009

Manchester

University of Bristol

BSc, Physics and Philosophy with study in Continental Europe / July, 2008

Bristol
Experience

Earlham Institute

Scientific programmer / November, 2015 — July, 2018

Genome assembly algorithm development

University of Manchester

Post doc bioinformatician in Nanomedicine group / June, 2019 — October, 2020

Wise range of bioinformatics tasks, mostly in RNASeq and Proteomics

Kromek

Associate Principal Scientist- Bioinformatics / November, 2020 — Present

Environmental metagenomics pipeline development for pathogen detection

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (11)
Computer Science Applications
Atomic and Molecular Physics, and Optics
Bioengineering
Pharmacology (medical)
Biochemistry (medical)
And 6 more
About
Katie Barr is a bioinformatician with a strong background in computer science. She received her Ph.D in Quantum Information from the University of Leeds in 2013. She also holds an MSc in Mathematical logic and the theory of computation from the University of Manchester, and a BSc in Physics and Philosophy with study in Continental Europe from the University of Bristol. Katie has extensive experience working in the fields of bioinformatics and software development. She has worked as a scientific programmer at the Earlham Institute, a postdoctoral bioinformatician in the Nanomedicine group at the University of Manchester, and is now an Associate Principal Scientist in Bioinformatics at Kromek. Katie is passionate about using her knowledge and skills to improve the lives of others and she is dedicated to the advancement of science and technology. She believes in the power of collaboration and works to create meaningful partnerships between industry and academia.
Most Relevant Publications (1+)

9 total publications

Deep Tissue Translocation of Graphene Oxide Sheets in Human Glioblastoma 3D Spheroids and an Orthotopic Xenograft Model

Advanced Therapeutics / Oct 09, 2020

de Lázaro, I., Sharp, P., Gurcan, C., Ceylan, A., Stylianou, M., Kisby, T., Chen, Y., Vranic, S., Barr, K., Taheri, H., Ozen, A., Bussy, C., Yilmazer, A., & Kostarelos, K. (2020). Deep Tissue Translocation of Graphene Oxide Sheets in Human Glioblastoma 3D Spheroids and an Orthotopic Xenograft Model. Advanced Therapeutics, 4(1). Portico. https://doi.org/10.1002/adtp.202000109

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Lindsay Webb, PhD

9 Years Experience
Immunologist and cancer biologist passionate about driving innovative research to improve patient health
Education

University of Cincinnati

BS, Cell and Molecular Biology / May, 2014

Cincinnati, Ohio, United States of America

The Ohio State University

Ph.D., Biomedical Sciences/ Immunology / December, 2018

Columbus, Ohio, United States of America
Experience

Dynamic Cell Therapies

Principal Scientist / May, 2023 — Present

TCR2 Therapeutics

Senior Scientist / May, 2021 — May, 2023

EMD Serono

Scientist / June, 2019 — May, 2021

Most Relevant Research Expertise
Pharmacology
Other Research Expertise (6)
Cancer Research
Immunology and Allergy
Molecular Medicine
Oncology
Immunology
And 1 more
About
Immunologist with expertise in T cell biology and molecular mechanisms of inflammation and anti-tumor immunity. Expert in drug development of biologics and cell therapies from early discovery to IND-enabling studies for oncology and autoimmune indications.
Most Relevant Publications (3+)

11 total publications

203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Ding, J., Webb, L., Patterson, T., Fleury, M., Zieba, A., Horton, H., Hofmeister, R., Gutierrez, D., & Tighe, R. (2021). 203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A214–A214. https://doi.org/10.1136/jitc-2021-sitc2021.203

173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Fleury, M., McCarthy, D., Horton, H., Anderson, C., Watt, A., Zieba, A., Webb, L., Ding, J., Tighe, R., Hofmeister, R., & Gutierrez, D. (2021). 173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A185–A185. https://doi.org/10.1136/jitc-2021-sitc2021.173

757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Xu, C., Rabinovich, B., Deshpande, A., Zhou, X., Pipp, F. C., Schweickhardt, R., Webb, L., Yalavarthi, S., Bourin, C., Ghatak, P., Safi, B., Wollerton, F., Brewis, N., Munoz-Olaya, J., Belousova, N., Alimzhanov, M., Hubensack, M., Halle, J.-P., Blaukat, A., & Moisan, J. (2021). 757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A792–A792. https://doi.org/10.1136/jitc-2021-sitc2021.757

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Example Pharmacology projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Pharmacology?

Optimizing Drug Formulations

A pharmaceutical company can collaborate with a Pharmacology expert to optimize the formulation of a drug, ensuring its stability, bioavailability, and therapeutic efficacy. The researcher can provide insights into the physicochemical properties of the drug, recommend suitable excipients, and suggest formulation strategies to enhance drug delivery and absorption.

Identifying New Drug Targets

By partnering with a Pharmacology researcher, a biotechnology company can identify novel drug targets for various diseases. The expert can analyze disease mechanisms, molecular pathways, and receptor interactions to identify potential therapeutic targets. This collaboration can lead to the development of innovative drugs with improved efficacy and specificity.

Improving Clinical Trial Design

A contract research organization (CRO) can collaborate with a Pharmacology expert to improve the design of clinical trials. The researcher can provide insights into appropriate dosing regimens, patient selection criteria, and outcome measures. This collaboration can enhance the efficiency and reliability of clinical trials, leading to faster drug approvals and reduced development costs.

Assessing Drug Safety and Efficacy

A pharmaceutical company can work with a Pharmacology expert to assess the safety and efficacy of their drugs. The researcher can conduct preclinical studies, evaluate drug-drug interactions, and assess potential adverse effects. This collaboration can help identify and mitigate safety risks, ensuring the development of safe and effective medications.

Navigating Regulatory Affairs

Companies can collaborate with Pharmacology experts to navigate the complex landscape of regulatory affairs. These researchers can provide guidance on regulatory requirements, assist in preparing documentation for regulatory submissions, and ensure compliance with safety and efficacy standards. This collaboration can streamline the regulatory process and expedite the approval of new drugs.