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Work with thought leaders and academic experts in Immunology

Companies can greatly benefit from working with experts in the field of Immunology. These researchers can provide valuable insights and expertise to enhance research and development efforts. They can help in the development of new drugs and therapies, conduct preclinical and clinical trials, and provide guidance on regulatory compliance. Additionally, Immunology experts can contribute to the understanding of disease mechanisms, identify potential biomarkers, and develop diagnostic tools. Their knowledge can also be applied in the fields of personalized medicine, immunotherapy, and vaccine development. Collaborating with Immunology researchers can lead to breakthrough discoveries, improved patient outcomes, and a competitive advantage in the healthcare industry.

Researchers on NotedSource with backgrounds in Immunology include Regan Hamel, Theresa Higgins, Dr. Lindsey Kuehm, Ph.D., Michael W Harman, Ping Luo, Elvira Forte, Susan Song, MD/PhD, Odion Ikhimiukor, Boris Leibovitch, Mohammad Imran Khan, Dr. David Siderovski, Ph.D., Dr. Justin Whalley, Ph.D, Rosani Matoso Silva, Ph.D., and Lindsay Webb, PhD.

Regan Hamel

Cambridge
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
Most Relevant Research Expertise
Immunology
Other Research Expertise (12)
single cell biology
transcriptomics
Cellular and Molecular Neuroscience
Cell Biology
Developmental Biology
And 7 more
About
Regan Hamel has an MPhil and PhD in Clinical Neurosciences from University of Cambridge. She also has a Bachelor of Science in Neurosciences from McGill University. Her PhD with Stefano Pluchino and John Marioni focused on single cell transcriptomics in the context of neuroinflammation. Since 2021 she has worked as a Bioinformatics scientist at Mogrify Ltd, applying a multitude of computational biology techniques (including single cell omics, bulk RNAseq, and predictive modelling) in the context of cell reprogramming
Most Relevant Publications (2+)

12 total publications

Metabolic Control of Smoldering Neuroinflammation

Frontiers in Immunology / Jun 23, 2021

Peruzzotti-Jametti, L., Willis, C. M., Hamel, R., Krzak, G., & Pluchino, S. (2021). Metabolic Control of Smoldering Neuroinflammation. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.705920

Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury

Frontiers in Immunology / Aug 24, 2022

Yao, X.-Q., Chen, J.-Y., Yu, Z.-H., Huang, Z.-C., Hamel, R., Zeng, Y.-Q., Huang, Z.-P., Tu, K.-W., Liu, J.-H., Lu, Y.-M., Zhou, Z.-T., Pluchino, S., Zhu, Q.-A., & Chen, J.-T. (2022). Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.964138

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Theresa Higgins

Auburn
Research Assistant II || Doctoral Student in Immunology
Most Relevant Research Expertise
immunology
Other Research Expertise (11)
osteosarcoma
cancer
CAR T
oncolytic virus
animal behavior
And 6 more
About
I am a current PhD student and experienced laboratory technician in molecular biology, with a strong background in avian behavior and ecology. My current research is focused on oncolytic virus and CAR T immunotherapies as treatment for osteosarcoma in a canine model. Additionally, I am passionate about scientific communication through interdisciplinary work and the arts.

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Dr. Lindsey Kuehm, Ph.D.

St. Louis, Missouri, United States of America
PhD immunologist specializing in cancer immunotherapy
Most Relevant Research Expertise
Immunology
Other Research Expertise (6)
Cancer Immunotherapy
CAR-T Cell Therapy
Cancer Research
T Cell Biology
Infectious Disease
And 1 more
About
I am passionate about science and bench to beside clinical research with 14 years of immunology and microbiology experience in both academia and industry.  My past research has focused on T cell immunology, CAR-T cells, and checkpoint blockade cancer immunotherapy. I am also very interested in researching immunotherapy for infectious diseases. My experiences have lead to finely tuned presentation skills and I have many years of experience mentoring high schoolers, undergrads, graduate, medical students, and other scientists.

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Michael W Harman

East Greenwich, RI, Rhode Island, United States of America
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Expertise
Immunology
Other Research Expertise (13)
Bacteria & Cell Bio-Physics
Biomechanics
Infectious Diseases
Microbiology
Parasitology
And 8 more
About
Highly skilled, energetic, and motivated professional empowered by over a decade of cross-disciplinary engineering and scientific applications experience. Presenting elegant solutions to prevalent biomedical challenges. Motivated by driving deliverable outcomes from complex research studies through effective leadership, active consulting work, and innovative problem-solving techniques. Seeking to make an immediate impact in a fast-paced biotechnology environment capitalizing on my advanced comprehension, continued professional growth, strategic product development expertise, and active network of personal connections across all areas of science, engineering, medicine, manufacturing and healthcare.
Most Relevant Publications (1+)

15 total publications

The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks

Infection and Immunity / Aug 01, 2011

Caimano, M. J., Kenedy, M. R., Kairu, T., Desrosiers, D. C., Harman, M., Dunham-Ems, S., Akins, D. R., Pal, U., & Radolf, J. D. (2011). The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks. Infection and Immunity, 79(8), 3117–3130. https://doi.org/10.1128/iai.05136-11

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Ping Luo

Toronto, Ontario, Canada
Bioinformatics Specialist at Princess Margaret Cancer Centre with experience in deep learning
Most Relevant Research Expertise
Immunology
Other Research Expertise (21)
single-cell genomics
deep learning
complex network analysis
Genetics (clinical)
Genetics
And 16 more
About
8 years of science and engineering experience integrating multi-omics data to identify biomarkers for cancer studies. Seeking to apply data analytics expertise to develop new diagnosis and treatment strategies.
Most Relevant Publications (1+)

23 total publications

Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma

Blood / Nov 05, 2021

Coffey, D. G., Maura, F., Gonzalez-Kozlova, E., Diaz-Mejia3, J., Luo, P., Zhang, Y., Xu, Y., Warren, E. H., Smith, E. L., Cho, H. J., Lesokhin, A., Diamond, B., Kazandjian, D., Pugh, T. J., Green, D. J., Gnjatic, S., & Landgren, O. (2021). Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma. Blood, 138(Supplement 1), 329–329. https://doi.org/10.1182/blood-2021-154506

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Elvira Forte

New York, New York, United States of America
Scientific strategist • Senior Scientist • Senior Scientific Editor
Most Relevant Research Expertise
Immunology
Other Research Expertise (26)
fibrosis
inflammation
cardiomyopathies
Physiology
Cardiology and Cardiovascular Medicine
And 21 more
About
Motivated and growth-driven biomedical scientist with over 15 years of experience in the cardiovascular field. Strong background in cell and molecular biology, data analysis, and interpretation. Seeking #newopportunities to deliver value as a Senior Scientist, Associate Principal Scientist, Scientific Liaison, or Scientific Consultant within a company that combines new technologies such as single-cell omics and AI for drug discovery and personalized medicine. <br> Throughout my career, I've used various in vivo and in vitro models to investigate the molecular and cellular mechanisms of fibrosis and inflammation in the heart, and how these mechanisms are affected in mice with different genetic backgrounds. My experience includes project management and mentoring. I completed three projects involving international collaborations, supervised two junior researchers, and taught cellular and molecular techniques to at least six professionals. As one of the launching editors and senior editor at Nature Cardiovascular Research, I oversaw the quality of the content published in the journal and the editorial process. I collaborated with authors, reviewers, and editors to ensure the highest standards of scientific rigor, relevance, and innovation. I also contributed to the journal's vision, strategy, and outreach, promoting the latest advances and discoveries in the cardiovascular and hematology fields. This experience has sharpened my analytical and communication skills and broadened my understanding of the field, covering a wide range of studies, from basic research to clinical, epidemiological, and public health research. My mission is to advance the knowledge and practice of cardiovascular medicine and to bridge the gap between research and clinical applications. Keywords: cardiovascular, #fibrosis, inflammation, cardioimmunology, RNA, single-cell biology, #transcriptomics, imaging, animal models, small animal surgery, and scientific writing.
Most Relevant Publications (2+)

63 total publications

HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice

The Journal of Immunology / Dec 15, 2023

Racine, J. J., Misherghi, A., Dwyer, J. R., Maser, R., Forte, E., Bedard, O., Sattler, S., Pugliese, A., Landry, L., Elso, C., Nakayama, M., Mannering, S., Rosenthal, N., & Serreze, D. V. (2023). HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. The Journal of Immunology, 211(12), 1792–1805. https://doi.org/10.4049/jimmunol.2300303

Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti–PD-1 Immune Checkpoint Inhibitor Cancer Therapy

The Journal of Immunology / Mar 01, 2024

Racine, J. J., Bachman, J. F., Zhang, J.-G., Misherghi, A., Khadour, R., Kaisar, S., Bedard, O., Jenkins, C., Abbott, A., Forte, E., Rainer, P., Rosenthal, N., Sattler, S., & Serreze, D. V. (2024). Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti–PD-1 Immune Checkpoint Inhibitor Cancer Therapy. The Journal of Immunology, 212(8), 1287–1306. https://doi.org/10.4049/jimmunol.2300841

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Susan Song, MD/PhD

Pittsburgh, Pennsylvania, United States of America
Research Assistant Professor in Neuroscience at University of Pittsburgh
Most Relevant Research Expertise
Immunology
Other Research Expertise (15)
microglia
white matter
neurodegenerative disease
Cellular and Molecular Neuroscience
Neurology
And 10 more
About
Susan Song, MD/PhD, is a highly accomplished neuroscientist, with extensive education and experience in the field. She received her MD/PhD in Neurology and Neuroscience from Southern Medical University in 2015, where she conducted groundbreaking research on the molecular mechanisms of neurodegenerative diseases. Following this, she completed a post-doctoral fellowship in Neuroscience at the University of Pittsburgh, where she continued to excel in her research and received numerous awards and grants for her work. Dr. Song's expertise lies in studying the underlying causes and potential treatments for various neurological diseases, such as ischemic stroke, traumatic brain injury, glioblastoma, Alzheimer's disease, and multiple sclerosis. She has a deep understanding of the brain and nervous system, and is constantly seeking new ways to unravel the complexities of these diseases. Dr. Song has held several prestigious positions throughout her career, including her current position as Research Assistant Professor at the University of Pittsburgh. She has published numerous articles in top scientific journals and presented her research at international conferences. Her findings have contributed greatly to the field of neurology and have the potential to improve the lives of millions of people suffering from neurological disorders. Overall, Dr. Song is a highly respected and accomplished physician-scientist who is making significant contributions to the field of neurology. With her extensive education, diverse experience, and unwavering dedication to her patients, she is a true leader in the field and a valuable asset to the medical community.
Most Relevant Publications (2+)

20 total publications

Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function

Journal of Neuroinflammation / Aug 28, 2021

Liu, Q., Bhuiyan, M. I. H., Liu, R., Song, S., Begum, G., Young, C. B., Foley, L. M., Chen, F., Hitchens, T. K., Cao, G., Chattopadhyay, A., He, L., & Sun, D. (2021). Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02234-8

Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury

Journal of Neuroinflammation / Oct 05, 2022

Song, S., Hasan, M. N., Yu, L., Paruchuri, S. S., Bielanin, J. P., Metwally, S., Oft, H. C. M., Fischer, S. G., Fiesler, V. M., Sen, T., Gupta, R. K., Foley, L. M., Hitchens, T. K., Dixon, C. E., Cambi, F., Sen, N., & Sun, D. (2022). Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. Journal of Neuroinflammation, 19(1). https://doi.org/10.1186/s12974-022-02608-6

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Odion Ikhimiukor

Albany, New York, United States of America
Postdoctoral Research Scientist at University at Albany, State University of New York
Most Relevant Research Expertise
Immunology
Other Research Expertise (23)
Pathogen Genomics
Bioinformatics
Molecular Biology
Epidemiology
Environmental Microbiology
And 18 more
About
A postdoctoral research scientist with over 9 years experience in bacterial genomics, microbiology, bioinformatics and antimicrobial resistance research. I’m seeking a Research Scientist or Epidemiologist role at public health genomics laboratories and I am the perfect fit for these roles because I have the following skills: molecular biology, research & development, strategic planning, project management, documentation, outbreak investigation, and cross-functional collaboration skills. I have leveraged my skills to work in a collaborative team-oriented environment to accomplish project goals related to examining the evolution of antimicrobial resistance as evidenced by over 7 national and international collaborations including the New York State Department of Health. I am also a proactive problem-solver adopting innovative and scientific thinking strategies in molecular biology to fulfill project objectives resulting in scientific discoveries including uncovering 1 novel hotspot for the dissemination of resistance in bacteria. I have gained mentorship expertise in promoting data reproducibility, and innovative research methodology in antimicrobial resistance research as evidenced by mentoring 10 professionals on evolutionary genomics, epidemiological statistics, and antimicrobial stewardship. I have also worked collaboratively with a team to apply pathogen genomics, bioinformatics, and leadership skills as demonstrated by working with over 10 highly collaborative teams including the Africa CDC. In addition, I have the following qualifications: Cross-functional collaborator and experience elucidating methods and frequencies of horizontal gene transfer and antimicrobial resistance spread in bacterial species, as demonstrated by 26 peer-reviewed publications including 1 in Nature Microbiology. Experience in leading and managing project details and tasks as evidenced by over 20 projects in pathogen genomics, epidemiology, antimicrobial resistance surveillance, and global health. Astute communication skills in bacterial epidemiology and antimicrobial resistance research resulting in 20 presentations and 6 travel awards to deliver such presentations, including the Bill and Melinda Gates Foundation. I want to serve an organization that prizes community, collaboration and humility among its employees. I’m excited to be on a team built around impact, innovation and a strong, positive reputation. I know I will thrive at a company where responsibility is valued, as well as self-improvement and time-management. I want to be a part of an organization that infuses growth into their brand, culture and market and who I can help make a difference in the world.
Most Relevant Publications (1+)

27 total publications

A bottom-up view of antimicrobial resistance transmission in developing countries

Nature Microbiology / May 30, 2022

Ikhimiukor, O. O., Odih, E. E., Donado-Godoy, P., & Okeke, I. N. (2022). A bottom-up view of antimicrobial resistance transmission in developing countries. Nature Microbiology, 7(6), 757–765. https://doi.org/10.1038/s41564-022-01124-w

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Boris Leibovitch

New York, New York, United States of America
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Most Relevant Research Expertise
Immunology
Other Research Expertise (8)
Cancer Research
Cell Biology
Developmental Biology
Molecular Biology
Hematology
And 3 more
About
I am experienced molecular and cell biologist with deep genetics background who worked many years in USA and Russia on the bench and as teacher. Both types of work had demanded extremely broad knowledge and understanding of developments in the fields. Participation in grant writing, editorial/reviewer work for scientific journals and consulting colleagues on these subjects added a lot to my broad experience as the scientist.
Most Relevant Publications (1+)

22 total publications

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Blood / Mar 15, 2008

Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122

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Mohammad Imran Khan

College Park, Maryland, United States of America
Postdoctoral Associate at University of Maryland College Park in the Department of Nutrition and Food Science
Most Relevant Research Expertise
Immunology
Other Research Expertise (22)
Biomedical Engineering
Nanotechology
Wound healing
Infection and Immunity
Bioengineering
And 17 more
About
Research work is focused on the formulation of nanoparticles encapsulated materials which could be useful for tissue engineering, stem cells, drug delivery and biomechanics to create biologically inspired tissue and organ constructs. Furthermore, 3D material may play significant role in the healing of complex tissues and organs in vitro and in vivo.
Most Relevant Publications (1+)

11 total publications

Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency

Medical Microbiology and Immunology / Oct 05, 2018

Khan, Md. I., Behera, S. K., Paul, P., Das, B., Suar, M., Jayabalan, R., Fawcett, D., Poinern, G. E. J., Tripathy, S. K., & Mishra, A. (2018). Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency. Medical Microbiology and Immunology, 208(5), 609–629. https://doi.org/10.1007/s00430-018-0564-z

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Dr. David Siderovski, Ph.D.

Fort Worth
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
Most Relevant Research Expertise
Immunology
Other Research Expertise (25)
Regulator of G protein Signaling (RGS) proteins
Pharmacology
Molecular Biology
Cellular and Molecular Neuroscience
Molecular Medicine
And 20 more
About
Dr. David Siderovski is a renowned scientist and academic, with a career spanning over two decades. He received his Ph.D. in Medical Biophysics from the University of Toronto in 1997, where he specialized in signal transduction and cellular signaling pathways. After completing his doctorate, Dr. Siderovski held various faculty positions at prestigious universities, including the University of North Carolina at Chapel Hill, West Virginia University School of Medicine, and the University of North Texas Health Science Center. At these institutions, Dr. Siderovski has made significant contributions to the field of pharmacology through his research on G protein-coupled receptors (GPCRs) and RGS proteins, which are key regulators of GPCR cellular signaling. His work has helped to advance the understanding of RGS proteins and their roles in various diseases, including cancer, cardiovascular disorders, and neurological disorders. In addition to his research, Dr. Siderovski is also a dedicated educator and mentor. He has taught and mentored numerous undergraduate, graduate, and medical students, and has served as a mentor for postdoctoral fellows and junior faculty members. He is known for his passion and enthusiasm for science and his ability to inspire and guide the next generation of scientists. Dr. Siderovski has received numerous awards and honors for his contributions to the scientific community. He was the recipient of the Abel Award in 2004 from the American Society of Pharmacology & Experimental Therapeutics for his pioneering discoveries of the RGS proteins and the GoLoco motif. He has also served on editorial boards of several scientific journals (including a decade at *J.Biol.Chem.*) and has been a member of various scientific committees, NIH study section panels, and pharma/biotech advisory boards, including for Inspire, Wyeth, and BellBrook Labs. Overall, Dr. David Siderovski is a highly accomplished and respected scientist and educator, whose research has had a significant impact on the field of pharmacology. His dedication and passion for science continue to inspire and influence the next generation of researchers in this field.
Most Relevant Publications (2+)

94 total publications

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

Immunity / Jun 01, 2012

Lei, Y., Wen, H., Yu, Y., Taxman, D. J., Zhang, L., Widman, D. G., Swanson, K. V., Wen, K.-W., Damania, B., Moore, C. B., Giguère, P. M., Siderovski, D. P., Hiscott, J., Razani, B., Semenkovich, C. F., Chen, X., & Ting, J. P.-Y. (2012). The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy. Immunity, 36(6), 933–946. https://doi.org/10.1016/j.immuni.2012.03.025

A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis

PLoS Pathogens / Feb 23, 2012

Bosch, D. E., Willard, F. S., Ramanujam, R., Kimple, A. J., Willard, M. D., Naqvi, N. I., & Siderovski, D. P. (2012). A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis. PLoS Pathogens, 8(2), e1002553. https://doi.org/10.1371/journal.ppat.1002553

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Dr. Justin Whalley, Ph.D

North Chicago, Illinois, United States of America
Assistant Professor of Bioinformatics, with experience in finding the quintessential features in large, multi-layered 'omic datasets.
Research Expertise (19)
Genomics
Bioinformatics
Immunity
Tensor decomposition
Cancer
And 14 more
About
Dr. Justin P. Whalley was educated in the UK (M.Sci. Mathematics, University of Bristol) and France (Ph.D. Bioinformatics, University of Évry). He moved to Spain to work as a postdoc at the National Center for Genomic Analysis (CNAG). During his time there, he ran the Quality Control working group for the Pan-Cancer Analysis of Whole Genomes project to assess the data coming in and reduce batch effects. This involved collaboration with researchers from the Broad Institute of MIT and Harvard, the German Cancer Research Center and the Wellcome Sanger Institute in the UK. He returned to the UK to work as a [Senior Bioinformatician at the University of Oxford](https://www.well.ox.ac.uk/people/jpw/). His time there coincided with the global pandemic and he was deeply involved in the COvid-19 Multi-omics Blood ATlas (COMBAT) consortium as the lead for the Integration (Tensor) working group. Dr. Whalley became a member of the [faculty of the Chicago Medical School at Rosalind Franklin University of Medicine and Science](https://www.rosalindfranklin.edu/academics/faculty/justin-p-whalley/) in January 2023.

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Rosani Matoso Silva, Ph.D.

Fulbrigther Humphrey Fellow 2023-2024 from Brazil
Most Relevant Research Expertise
Immunology
Other Research Expertise (7)
Zootecnia
Food Animals
Animal Science and Zoology
Safety, Risk, Reliability and Quality
Food Science
And 2 more
About
Rosani Matoso Silva is a scientific researcher and activist committed to advancing diversity and black and indigenous leadership in the fields of science and technology (S&T). Her passion and dedication to these causes led her to establish the Mancala Institute, where she serves as the director of research, spearheading innovative projects aimed at developing technological solutions to address social and racial disparities across Brazil. Rosani’s research is deeply influenced by her belief in the need for innovative methods to effectively monitor food insecurity, a critical issue affecting countless vulnerable communities. Rosani was selected for the prestigious Humphrey Fellowship program for 2023-2024, an opportunity that reflects her exceptional commitment and leadership potential. During the program, she seeks to enhance her leadership development, networking, and negotiation skills. Her goal is to build a supportive network with American organizations focused on achieving food security and sovereignty for vulnerable communities, thus expanding the impact of her work and contributing to the creation of a more just and inclusive future. Rosani Matoso Silva is a driving force in the fight for inclusion and social justice in the fields of science and technology, with an unwavering dedication to creating a world where diversity is not only recognized but valued and promoted.
Most Relevant Publications (1+)

16 total publications

Anaphylaxis to lipid transfer protein from sunflower seeds

Allergy / Sep 07, 2010

Yagami, A. (2010). Anaphylaxis to lipid transfer protein from sunflower seeds. Allergy, 65(10), 1340–1341. Portico. https://doi.org/10.1111/j.1398-9995.2010.02337.x

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Lindsay Webb, PhD

Immunologist and cancer biologist passionate about driving innovative research to improve patient health
Most Relevant Research Expertise
Immunology
Other Research Expertise (6)
Cancer Research
Immunology and Allergy
Molecular Medicine
Pharmacology
Oncology
And 1 more
About
Immunologist with expertise in T cell biology and molecular mechanisms of inflammation and anti-tumor immunity. Expert in drug development of biologics and cell therapies from early discovery to IND-enabling studies for oncology and autoimmune indications.
Most Relevant Publications (7+)

11 total publications

203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Ding, J., Webb, L., Patterson, T., Fleury, M., Zieba, A., Horton, H., Hofmeister, R., Gutierrez, D., & Tighe, R. (2021). 203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A214–A214. https://doi.org/10.1136/jitc-2021-sitc2021.203

173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Fleury, M., McCarthy, D., Horton, H., Anderson, C., Watt, A., Zieba, A., Webb, L., Ding, J., Tighe, R., Hofmeister, R., & Gutierrez, D. (2021). 173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A185–A185. https://doi.org/10.1136/jitc-2021-sitc2021.173

M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation

Cancer Immunology Research / Dec 13, 2023

Xu, C., Zhou, X., Webb, L., Yalavarthi, S., Zheng, W., Saha, S., Schweickhardt, R., Soloviev, M., Jenkins, M. H., Brandstetter, S., Belousova, N., Alimzhanov, M., Rabinovich, B., Deshpande, A. M., Brewis, N., & Helming, L. (2023). M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation. Cancer Immunology Research, 12(2), 195–213. https://doi.org/10.1158/2326-6066.cir-23-0243

Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models

Cancer Immunology Research / Jan 01, 2022

Xu, C., Webb, L., Yalavarthi, S., Bourin, C., & Moisan, J. (2022). Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models. Cancer Immunology Research, 10(1_Supplement), P077–P077. https://doi.org/10.1158/2326-6074.tumimm21-p077

757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity

Journal for ImmunoTherapy of Cancer / Nov 01, 2021

Xu, C., Rabinovich, B., Deshpande, A., Zhou, X., Pipp, F. C., Schweickhardt, R., Webb, L., Yalavarthi, S., Bourin, C., Ghatak, P., Safi, B., Wollerton, F., Brewis, N., Munoz-Olaya, J., Belousova, N., Alimzhanov, M., Hubensack, M., Halle, J.-P., Blaukat, A., & Moisan, J. (2021). 757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A792–A792. https://doi.org/10.1136/jitc-2021-sitc2021.757

NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms

Frontiers in Immunology / Mar 19, 2019

Webb, L. M., Narvaez Miranda, J., Amici, S. A., Sengupta, S., Nagy, G., & Guerau-de-Arellano, M. (2019). NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.00524

PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis

The Journal of Immunology / Feb 15, 2017

Webb, L. M., Amici, S. A., Jablonski, K. A., Savardekar, H., Panfil, A. R., Li, L., Zhou, W., Peine, K., Karkhanis, V., Bachelder, E. M., Ainslie, K. M., Green, P. L., Li, C., Baiocchi, R. A., & Guerau-de-Arellano, M. (2017). PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. The Journal of Immunology, 198(4), 1439–1451. https://doi.org/10.4049/jimmunol.1601702

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Example Immunology projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Immunology?

Development of Novel Immunotherapies

An Immunology expert can collaborate with a pharmaceutical company to develop novel immunotherapies for the treatment of cancer and autoimmune diseases. Their expertise in understanding the immune system and its response to diseases can help in identifying new targets and designing effective therapies.

Drug Discovery and Development

Companies can collaborate with Immunology researchers to discover and develop new drugs. These experts can provide insights into disease mechanisms, identify potential drug targets, and evaluate the efficacy and safety of drug candidates through preclinical and clinical trials.

Biomarker Identification

Immunology experts can assist companies in identifying biomarkers that can be used for disease diagnosis, prognosis, and monitoring. These biomarkers can help in early detection, personalized treatment approaches, and assessing treatment response.

Vaccine Development

Collaborating with Immunology researchers can accelerate the development of vaccines. Their knowledge of immune responses to pathogens can aid in the design and optimization of vaccines, ensuring their effectiveness and safety.

Personalized Medicine

Immunology experts can contribute to the field of personalized medicine by understanding individual variations in immune responses. This knowledge can help in tailoring treatment approaches based on a patient's immune profile, leading to improved therapeutic outcomes.