Work with thought leaders and academic experts in Immunology
Companies can greatly benefit from working with experts in the field of Immunology. These researchers can provide valuable insights and expertise to enhance research and development efforts. They can help in the development of new drugs and therapies, conduct preclinical and clinical trials, and provide guidance on regulatory compliance. Additionally, Immunology experts can contribute to the understanding of disease mechanisms, identify potential biomarkers, and develop diagnostic tools. Their knowledge can also be applied in the fields of personalized medicine, immunotherapy, and vaccine development. Collaborating with Immunology researchers can lead to breakthrough discoveries, improved patient outcomes, and a competitive advantage in the healthcare industry.
Researchers on NotedSource with backgrounds in Immunology include Regan Hamel, Dr. David Siderovski, Ph.D., Shariq Usmani, PhD, Michael W Harman, Ping Luo, Theresa Higgins, Dr. Lindsey Kuehm, Ph.D., Joseph Bucukovski, Ph.D., Boris Leibovitch, Mohammad Imran Khan, Elvira Forte, Susan Song, MD/PhD, Odion Ikhimiukor, and Brendan Monogue, Ph.D..
Regan Hamel
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
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Other Research Expertise (12)
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Most Relevant Publications (2+)
12 total publications
Metabolic Control of Smoldering Neuroinflammation
Frontiers in Immunology / Jun 23, 2021
Peruzzotti-Jametti, L., Willis, C. M., Hamel, R., Krzak, G., & Pluchino, S. (2021). Metabolic Control of Smoldering Neuroinflammation. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.705920
Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury
Frontiers in Immunology / Aug 24, 2022
Yao, X.-Q., Chen, J.-Y., Yu, Z.-H., Huang, Z.-C., Hamel, R., Zeng, Y.-Q., Huang, Z.-P., Tu, K.-W., Liu, J.-H., Lu, Y.-M., Zhou, Z.-T., Pluchino, S., Zhu, Q.-A., & Chen, J.-T. (2022). Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.964138
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Dr. David Siderovski, Ph.D.
Professor of Computational Pharmacology; Chair of HSC SBS Dept. of Pharmacology & Neuroscience
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Other Research Expertise (25)
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Most Relevant Publications (2+)
94 total publications
The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy
Immunity / Jun 01, 2012
Lei, Y., Wen, H., Yu, Y., Taxman, D. J., Zhang, L., Widman, D. G., Swanson, K. V., Wen, K.-W., Damania, B., Moore, C. B., Giguère, P. M., Siderovski, D. P., Hiscott, J., Razani, B., Semenkovich, C. F., Chen, X., & Ting, J. P.-Y. (2012). The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy. Immunity, 36(6), 933–946. https://doi.org/10.1016/j.immuni.2012.03.025
A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
PLoS Pathogens / Feb 23, 2012
Bosch, D. E., Willard, F. S., Ramanujam, R., Kimple, A. J., Willard, M. D., Naqvi, N. I., & Siderovski, D. P. (2012). A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis. PLoS Pathogens, 8(2), e1002553. https://doi.org/10.1371/journal.ppat.1002553
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Shariq Usmani, PhD
Massachusetts General Hospital, Harvard Medical School
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Other Research Expertise (9)
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Most Relevant Publications (7+)
22 total publications
Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein
PLoS Pathogens / Dec 20, 2012
Sauter, D., Unterweger, D., Vogl, M., Usmani, S. M., Heigele, A., Kluge, S. F., Hermkes, E., Moll, M., Barker, E., Peeters, M., Learn, G. H., Bibollet-Ruche, F., Fritz, J. V., Fackler, O. T., Hahn, B. H., & Kirchhoff, F. (2012). Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein. PLoS Pathogens, 8(12), e1003093. https://doi.org/10.1371/journal.ppat.1003093
Liquefaction of Semen Generates and Later Degrades a Conserved Semenogelin Peptide That Enhances HIV Infection
Journal of Virology / Jul 01, 2014
Roan, N. R., Liu, H., Usmani, S. M., Neidleman, J., Müller, J. A., Avila-Herrera, A., Gawanbacht, A., Zirafi, O., Chu, S., Dong, M., Kumar, S. T., Smith, J. F., Pollard, K. S., Fändrich, M., Kirchhoff, F., Münch, J., Witkowska, H. E., & Greene, W. C. (2014). Liquefaction of Semen Generates and Later Degrades a Conserved Semenogelin Peptide That Enhances HIV Infection. Journal of Virology, 88(13), 7221–7234. https://doi.org/10.1128/jvi.00269-14
Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4 + T Cell Counts in Viremic HIV-2 Infection
Journal of Virology / May 01, 2012
Khalid, M., Yu, H., Sauter, D., Usmani, S. M., Schmokel, J., Feldman, J., Gruters, R. A., van der Ende, M. E., Geyer, M., Rowland-Jones, S., Osterhaus, A. D., & Kirchhoff, F. (2012). Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4 + T Cell Counts in Viremic HIV-2 Infection. Journal of Virology, 86(9), 4906–4920. https://doi.org/10.1128/jvi.06856-11
Molecular basis of early epithelial response to streptococcal exotoxin: role of STIM1 and Orai1 proteins
Cellular Microbiology / Dec 13, 2011
Usmani, S. M., von Einem, J., Frick, M., Miklavc, P., Mayenburg, M., Husmann, M., Dietl, P., & Wittekindt, O. H. (2011). Molecular basis of early epithelial response to streptococcal exotoxin: role of STIM1 and Orai1 proteins: Streptolysin O activates SOC entry. Cellular Microbiology, 14(3), 299–315. https://doi.org/10.1111/j.1462-5822.2011.01724.x
Lentiviral Nef Proteins Manipulate T Cells in a Subset-Specific Manner
Journal of Virology / Feb 15, 2015
Yu, H., Khalid, M., Heigele, A., Schmökel, J., M. Usmani, S., van der Merwe, J., Münch, J., Silvestri, G., & Kirchhoff, F. (2015). Lentiviral Nef Proteins Manipulate T Cells in a Subset-Specific Manner. Journal of Virology, 89(4), 1986–2001. https://doi.org/10.1128/jvi.03104-14
Cancer cells relax and resist cytotoxic attack
Immunity / May 01, 2021
Usmani, S. M., & Mempel, T. R. (2021). Cancer cells relax and resist cytotoxic attack. Immunity, 54(5), 853–855. https://doi.org/10.1016/j.immuni.2021.04.017
HIV-enhancing Amyloids Are Prevalent in Fresh Semen and Are a Determinant for Semen's Ability to Enhance HIV Infection: Relevance for HIV Transmission
AIDS Research and Human Retroviruses / Oct 01, 2014
Usmani, S., Liu, H., Pilcher, C. D., Witkowska, H. E., Kirchhoff, F., Greene, W. C., Münch, J., & Roan, N. R. (2014). HIV-enhancing Amyloids Are Prevalent in Fresh Semen and Are a Determinant for Semen’s Ability to Enhance HIV Infection: Relevance for HIV Transmission. AIDS Research and Human Retroviruses, 30(S1), A183–A184. https://doi.org/10.1089/aid.2014.5392.abstract
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Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
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Other Research Expertise (13)
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15 total publications
The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks
Infection and Immunity / Aug 01, 2011
Caimano, M. J., Kenedy, M. R., Kairu, T., Desrosiers, D. C., Harman, M., Dunham-Ems, S., Akins, D. R., Pal, U., & Radolf, J. D. (2011). The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks. Infection and Immunity, 79(8), 3117–3130. https://doi.org/10.1128/iai.05136-11
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Ping Luo
Bioinformatics Specialist at Princess Margaret Cancer Centre with experience in deep learning
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Other Research Expertise (21)
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Most Relevant Publications (1+)
23 total publications
Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma
Blood / Nov 05, 2021
Coffey, D. G., Maura, F., Gonzalez-Kozlova, E., Diaz-Mejia3, J., Luo, P., Zhang, Y., Xu, Y., Warren, E. H., Smith, E. L., Cho, H. J., Lesokhin, A., Diamond, B., Kazandjian, D., Pugh, T. J., Green, D. J., Gnjatic, S., & Landgren, O. (2021). Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma. Blood, 138(Supplement 1), 329–329. https://doi.org/10.1182/blood-2021-154506
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Boris Leibovitch
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
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Other Research Expertise (8)
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22 total publications
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
Blood / Mar 15, 2008
Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122
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Mohammad Imran Khan
Postdoctoral Associate at University of Maryland College Park in the Department of Nutrition and Food Science
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Other Research Expertise (22)
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11 total publications
Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency
Medical Microbiology and Immunology / Oct 05, 2018
Khan, Md. I., Behera, S. K., Paul, P., Das, B., Suar, M., Jayabalan, R., Fawcett, D., Poinern, G. E. J., Tripathy, S. K., & Mishra, A. (2018). Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency. Medical Microbiology and Immunology, 208(5), 609–629. https://doi.org/10.1007/s00430-018-0564-z
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Elvira Forte
Scientific strategist • Senior Scientist • Senior Scientific Editor
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63 total publications
HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice
The Journal of Immunology / Dec 15, 2023
Racine, J. J., Misherghi, A., Dwyer, J. R., Maser, R., Forte, E., Bedard, O., Sattler, S., Pugliese, A., Landry, L., Elso, C., Nakayama, M., Mannering, S., Rosenthal, N., & Serreze, D. V. (2023). HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. The Journal of Immunology, 211(12), 1792–1805. https://doi.org/10.4049/jimmunol.2300303
Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti–PD-1 Immune Checkpoint Inhibitor Cancer Therapy
The Journal of Immunology / Mar 01, 2024
Racine, J. J., Bachman, J. F., Zhang, J.-G., Misherghi, A., Khadour, R., Kaisar, S., Bedard, O., Jenkins, C., Abbott, A., Forte, E., Rainer, P., Rosenthal, N., Sattler, S., & Serreze, D. V. (2024). Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti–PD-1 Immune Checkpoint Inhibitor Cancer Therapy. The Journal of Immunology, 212(8), 1287–1306. https://doi.org/10.4049/jimmunol.2300841
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Susan Song, MD/PhD
Research Assistant Professor in Neuroscience at University of Pittsburgh
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20 total publications
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function
Journal of Neuroinflammation / Aug 28, 2021
Liu, Q., Bhuiyan, M. I. H., Liu, R., Song, S., Begum, G., Young, C. B., Foley, L. M., Chen, F., Hitchens, T. K., Cao, G., Chattopadhyay, A., He, L., & Sun, D. (2021). Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02234-8
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury
Journal of Neuroinflammation / Oct 05, 2022
Song, S., Hasan, M. N., Yu, L., Paruchuri, S. S., Bielanin, J. P., Metwally, S., Oft, H. C. M., Fischer, S. G., Fiesler, V. M., Sen, T., Gupta, R. K., Foley, L. M., Hitchens, T. K., Dixon, C. E., Cambi, F., Sen, N., & Sun, D. (2022). Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. Journal of Neuroinflammation, 19(1). https://doi.org/10.1186/s12974-022-02608-6
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Odion Ikhimiukor
Postdoctoral Research Scientist at University at Albany, State University of New York
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Other Research Expertise (23)
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27 total publications
A bottom-up view of antimicrobial resistance transmission in developing countries
Nature Microbiology / May 30, 2022
Ikhimiukor, O. O., Odih, E. E., Donado-Godoy, P., & Okeke, I. N. (2022). A bottom-up view of antimicrobial resistance transmission in developing countries. Nature Microbiology, 7(6), 757–765. https://doi.org/10.1038/s41564-022-01124-w
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Example Immunology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Immunology?
Development of Novel Immunotherapies
An Immunology expert can collaborate with a pharmaceutical company to develop novel immunotherapies for the treatment of cancer and autoimmune diseases. Their expertise in understanding the immune system and its response to diseases can help in identifying new targets and designing effective therapies.
Drug Discovery and Development
Companies can collaborate with Immunology researchers to discover and develop new drugs. These experts can provide insights into disease mechanisms, identify potential drug targets, and evaluate the efficacy and safety of drug candidates through preclinical and clinical trials.
Biomarker Identification
Immunology experts can assist companies in identifying biomarkers that can be used for disease diagnosis, prognosis, and monitoring. These biomarkers can help in early detection, personalized treatment approaches, and assessing treatment response.
Vaccine Development
Collaborating with Immunology researchers can accelerate the development of vaccines. Their knowledge of immune responses to pathogens can aid in the design and optimization of vaccines, ensuring their effectiveness and safety.
Personalized Medicine
Immunology experts can contribute to the field of personalized medicine by understanding individual variations in immune responses. This knowledge can help in tailoring treatment approaches based on a patient's immune profile, leading to improved therapeutic outcomes.