Work with thought leaders and academic experts in Pharmaceutical Science
Companies can greatly benefit from working with experts in the field of Pharmaceutical Science. These researchers bring a wealth of knowledge and experience that can contribute to various aspects of a company's operations. Here are some ways companies can collaborate with academic researchers in Pharmaceutical Science: 1. Research and Development: Academic researchers can provide valuable insights and expertise in developing new drugs, formulations, and delivery systems. They can contribute to the discovery of novel compounds, conduct preclinical and clinical trials, and optimize drug efficacy and safety. 2. Innovation and Technology Transfer: Pharmaceutical Science researchers can help companies stay at the forefront of innovation by transferring cutting-edge technologies and research findings. They can assist in the development of new drug delivery methods, formulation techniques, and manufacturing processes. 3. Regulatory Compliance: Academic researchers are well-versed in regulatory requirements and can assist companies in navigating complex regulatory frameworks. They can provide guidance on compliance with FDA regulations, quality control, and safety standards. 4. Collaboration on Grants and Funding: Academic researchers often have access to funding opportunities and can collaborate with companies on grant applications. They can help companies secure research grants and funding for collaborative projects. 5. Education and Training: Pharmaceutical Science researchers can provide training and education to company employees. They can conduct workshops, seminars, and training programs to enhance the knowledge and skills of the company's workforce.
Researchers on NotedSource with backgrounds in Pharmaceutical Science include Keisha Walters, Elvira Forte, Joel T. Nadler, Aimee Eggler, Professor(Dr) Sanjay Rout, Katie Barr, Maurice O'Sullivan, Yuan Yang, VIJAYASSHEKAR MANUKONDA, Giuseppe Maria de Peppo, Ratshilumela Steve Dima, Kamal Al-Malah, Ph.D., Morgan Edwards, Jessica D. Hess, Ph.D., and Thaddeus Allen.
Keisha Walters
University of Arkansas
Education
Clemson University
PhD, Chemical Engineering / 2005
Clemson University
BS, Biological Sciences / 1996
Clemson University
M.S., Chemical Engineering / May, 2001
Experience
University of Arkansas College of Engineering
Endowed Chair and Professor of Chemical Engineering / August, 2021 — Present
University of Oklahoma
Professor of Chemical, Biological and Materials Engineering / 2016 — 2021
Developing a world-class research program in stimuli reponsive polymers and polymer-grafted nanoparticles for biomedical, energy, and environmental applications. Committed to balance and excellence in research scholarship, teaching scholarship, and service to the profession. Passionate about instilling a love of learning and curiosity about how the world works physically in future generations.
Mississippi State University
Professor of Engineering / 2005 — 2016
Professor of Chemical Engineering who is committed to research, teaching, and service. My research is focused on polymer and nanoparticle-based material design, including ‘smart’ stimuli responsive polymers, polymer-nanoparticle constructs for biomedical and energy applications, and bio-based products such as polymers and fuels.
Most Relevant Research Expertise
Other Research Expertise (34)
About
Most Relevant Publications (2+)
102 total publications
Mesoporous Silica Nanoparticles: Properties and Strategies for Enhancing Clinical Effect
Pharmaceutics / Apr 17, 2021
Frickenstein, A. N., Hagood, J. M., Britten, C. N., Abbott, B. S., McNally, M. W., Vopat, C. A., Patterson, E. G., MacCuaig, W. M., Jain, A., Walters, K. B., & McNally, L. R. (2021). Mesoporous Silica Nanoparticles: Properties and Strategies for Enhancing Clinical Effect. Pharmaceutics, 13(4), 570. https://doi.org/10.3390/pharmaceutics13040570
Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa
Journal of Nanobiotechnology / Mar 17, 2016
Vasquez, E. S., Feugang, J. M., Willard, S. T., Ryan, P. L., & Walters, K. B. (2016). Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa. Journal of Nanobiotechnology, 14(1). https://doi.org/10.1186/s12951-016-0168-y
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Elvira Forte
Scientific strategist • Senior Scientist • Senior Scientific Editor
Education
Sapienza University of Rome
PhD, Pasteurian Sciences / January, 2011
Sapienza University of Rome
Master, Medical, Molecular and Cellular Biotechnology / October, 2006
Sapienza University of Rome
Bachelor, Biotechnology / October, 2004
Experience
Springer Nature
Associate/Senior Editor / June, 2021 — February, 2024
Helped shape and launch a new journal, Nature Cardiovascular Research, which publishes exceptional advances in the fields of cardiac, vascular, and blood biology, covering fundamental, translational, clinical, and public health research. • Assessed the novelty and impact of manuscripts within all the topics covered by the journal and chaperoned the whole revision process until acceptance for over 40% of all the content published by the journal since its start, with optimal processing times and excellent feedback from the authors. • Interfaced with scientists around the World, provided scientific guidance on how to improve manuscripts, or recommended more appropriate journals to publish with. Commissioned Comments, Reviews, News and Views on current topics, and summarized novel scientific findings in meaningful snippets and Research Highlights. • Contributed to the training and supervision of 2 Associate Editors; covered the Chief Editor's functions when needed.
Research Fellow/Associate Research Scientist / January, 2017 — June, 2021
• Analyzed the dynamic cellular changes during the fibrotic repair post-myocardial infarction, using cutting-edge techniques such as single-cell RNAseq with 10xChromium. Learned how to perform myocardial infarction in mice and assess the cardiac function via echography; analyze scRNAseq data using the Seurat package on R studio. • Completed a project aimed to characterize similarities and differences among fibroblasts from different organs cultured in the same conditions. Through cytometric, transcriptomic analysis, functional assays, shRNA and CRISPR-Cas9-mediated in vitro gene knockdowns we showed that fibroblasts isolated from different organs retain the expression of key transcription factors reflecting their embryological origin. • Collaborated with other laboratories in the Institute to design new mice models that could possibly recapitulate the symptoms of COVID-19; to analyze the response of mice with diverse genetic backgrounds to stressors.
Post-doctoral fellow/ Co-joint lecturer / May, 2013 — November, 2016
Developed projects aimed at understanding the embryological origin and function of a population of putative progenitor cells, cardiac colony forming unit fibroblasts cCFU-F, identified 2 years before in the lab (PMID: 22136928). • Performed cell lineage tracing and designed in vitro and in vivo cellular assays to assess the functional and immunomodulatory properties of PDGFRa+ fibroblasts in homeostasis and post-myocardial infarction with or without treatment with the PDGF-AB ligands. The data, presented in 3 international conferences and included in a preprint manuscript, have supported the use of a short-term treatment with PDGF-AB in a preclinical model of acute myocardial infarction in pigs. • Co-supervised 2 Ph.D. students at University of New South Wales
Scientific Editor / March, 2024 — Present
Consultant freelancer position within a team of former journal editors and grants specialists • Helped scientists increase the impact of their science by providing advice, in-depth editing, and feedback on manuscripts.
Most Relevant Research Expertise
Other Research Expertise (26)
About
Most Relevant Publications (1+)
63 total publications
A Chemical Biology Approach to Myocardial Regeneration
Journal of Cardiovascular Translational Research / Mar 22, 2011
Willems, E., Lanier, M., Forte, E., Lo, F., Cashman, J., & Mercola, M. (2011). A Chemical Biology Approach to Myocardial Regeneration. Journal of Cardiovascular Translational Research, 4(3), 340–350. https://doi.org/10.1007/s12265-011-9270-6
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Joel T. Nadler
Former Professor of Psychology, SIUE: Senior Consultant PDRI
Education
Southern Illinois University Carbondale
Ph.D., Applied (Industrial / Organizational) Psychology / August, 2010
Experience
Southern Illinois University Edwardsville
Professor: Director I/O Masters Program / August, 2010 — August, 2022
AON Assessment Solutions
Senior Consultant / July, 2022 — March, 2024
PDRI
Senior Consultant / April, 2024 — Present
Most Relevant Research Expertise
Other Research Expertise (18)
About
Most Relevant Publications (2+)
47 total publications
Sex Differences in Delaying Family: Effects on Job and Life Satisfaction
Journal of Psychology Research / Jun 28, 2011
Joshua Doerner, Joel T. Nadler, & Meghan R. Lowery. (2011). Sex Differences in Delaying Family: Effects on Job and Life Satisfaction. Journal of Psychology Research, 1(6). https://doi.org/10.17265/2159-5542/2011.06.006
Research Report: Implicit and Explicit Measures of Sexism Predicting Men’s Interviewing Behaviors
Journal of Organizational Psychology / Dec 30, 2020
Research Report: Implicit and Explicit Measures of Sexism Predicting Men’s Interviewing Behaviors. (2020). Journal of Organizational Psychology, 20(5). https://doi.org/10.33423/jop.v20i5.3693
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Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
Education
University of California, Santa Cruz
BS, Chemistry / May, 1996
University of Wisconsin–Madison
Ph.D., Biochemistry / May, 2002
Experience
Villanova University
Associate Professor of Chemistry / 2019 — Present
Villanova University
Assistant Professor / 2012 — 2019
Purdue University
Research Assistant Professor / 2010 — 2012
Most Relevant Research Expertise
Other Research Expertise (18)
About
Most Relevant Publications (2+)
25 total publications
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding
Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013
Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112
Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds
Molecules / Apr 03, 2000
Peterson, C., Tsao, R., Eggler, A., & Coats, J. (2000). Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds. Molecules, 5(12), 648–654. https://doi.org/10.3390/50400648
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Professor(Dr) Sanjay Rout
Industry Expert Dr. Sanjay - Former Honorary Chancellor, Leading Chair Professor and Advisory Consultant for Research and Development Forums.
Education
The Wharton Business School
Business Analytics
Magadh University
Ph.D, Management / March, 2017
Institute of management technology
PGDSCM, Management / October, 2009
Experience
Mahavideha University
Chancellor / June, 2021 — March, 2023
Innovation Solution Lab
CEO / October, 2019 — May, 2021
Spiritual Data
Board of Directors / July, 2023 — Present
Board of directors
Most Relevant Research Expertise
Other Research Expertise (14)
About
Most Relevant Publications (1+)
32 total publications
Some Current Publications
Restoration: Studies in English Literary Culture, 1660-1700 / Jan 01, 2013
Smith, M. (2013). Some Current Publications. Restoration: Studies in English Literary Culture, 1660-1700, 37(2), 91–100. https://doi.org/10.1353/rst.2013.0019
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Katie Barr
Bioinformatician and developer with strong academic and commercial experience
Education
University of Leeds
Ph.D, Quantum Information / December, 2013
University of Manchester
MSc, Mathematical logic and the theory of computation / December, 2009
University of Bristol
BSc, Physics and Philosophy with study in Continental Europe / July, 2008
Experience
Earlham Institute
Scientific programmer / November, 2015 — July, 2018
Genome assembly algorithm development
University of Manchester
Post doc bioinformatician in Nanomedicine group / June, 2019 — October, 2020
Wise range of bioinformatics tasks, mostly in RNASeq and Proteomics
Kromek
Associate Principal Scientist- Bioinformatics / November, 2020 — Present
Environmental metagenomics pipeline development for pathogen detection
Most Relevant Research Expertise
Other Research Expertise (11)
About
Most Relevant Publications (2+)
9 total publications
Deep Tissue Translocation of Graphene Oxide Sheets in Human Glioblastoma 3D Spheroids and an Orthotopic Xenograft Model
Advanced Therapeutics / Oct 09, 2020
de Lázaro, I., Sharp, P., Gurcan, C., Ceylan, A., Stylianou, M., Kisby, T., Chen, Y., Vranic, S., Barr, K., Taheri, H., Ozen, A., Bussy, C., Yilmazer, A., & Kostarelos, K. (2020). Deep Tissue Translocation of Graphene Oxide Sheets in Human Glioblastoma 3D Spheroids and an Orthotopic Xenograft Model. Advanced Therapeutics, 4(1). Portico. https://doi.org/10.1002/adtp.202000109
Graphene Oxide Nanoscale Platform Enhances the Anti‐Cancer Properties of Bortezomib in Glioblastoma Models
Advanced Healthcare Materials / Nov 11, 2022
Sharp, P. S., Stylianou, M., Arellano, L. M., Neves, J. C., Gravagnuolo, A. M., Dodd, A., Barr, K., Lozano, N., Kisby, T., & Kostarelos, K. (2022). Graphene Oxide Nanoscale Platform Enhances the Anti‐Cancer Properties of Bortezomib in Glioblastoma Models. Advanced Healthcare Materials, 12(3). Portico. https://doi.org/10.1002/adhm.202201968
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Maurice O'Sullivan
University College Cork, School of Food and Nutritional Sciences
Education
Sensory and Consumer Science / March, 2002
Experience
Univsersity College Cork
Most Relevant Research Expertise
Other Research Expertise (33)
About
Most Relevant Publications (1+)
85 total publications
Dietary Compounds Influencing the Sensorial, Volatile and Phytochemical Properties of Bovine Milk
Molecules / Dec 19, 2019
Clarke, H. J., Griffin, C., Rai, D. K., O’Callaghan, T. F., O’Sullivan, M. G., Kerry, J. P., & Kilcawley, K. N. (2019). Dietary Compounds Influencing the Sensorial, Volatile and Phytochemical Properties of Bovine Milk. Molecules, 25(1), 26. https://doi.org/10.3390/molecules25010026
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Yuan Yang
Assistant Professor at Columbia University
Education
Stanford University
PhD, Materials Science and Engineering / June, 2012
Peking University
B.S., Physics / July, 2007
Experience
Columbia University
Assistant Professor / July, 2012 — Present
Massachusetts Institute of Technology
Postdoc / July, 2012 — June, 2015
Most Relevant Research Expertise
Other Research Expertise (32)
About
Most Relevant Publications (2+)
142 total publications
Characterization of Water Self-Diffusion in Human Stratum Corneum
Journal of Pharmaceutical Sciences / Apr 01, 2018
Kodiweera, C., Yang, Y., & Bunge, A. L. (2018). Characterization of Water Self-Diffusion in Human Stratum Corneum. Journal of Pharmaceutical Sciences, 107(4), 1131–1142. https://doi.org/10.1016/j.xphs.2017.12.011
Characterization of Water and a Model Lipophilic Compound in Human Stratum Corneum by NMR Spectroscopy and Equilibrium Sorption
Journal of Pharmaceutical Sciences / Nov 01, 2016
Kodiweera, C., Romonchuk, W. J., Yang, Y., & Bunge, A. L. (2016). Characterization of Water and a Model Lipophilic Compound in Human Stratum Corneum by NMR Spectroscopy and Equilibrium Sorption. Journal of Pharmaceutical Sciences, 105(11), 3376–3386. https://doi.org/10.1016/j.xphs.2016.08.010
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VIJAYASSHEKAR MANUKONDA
Biotechnologist with core competence in biochemistry/cell-biology/molecular biology
Education
Jawaharlal Nehru Technological University, Hyderabad
BIOTECHNOLOGY / February, 2014
Experience
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Most Relevant Research Expertise
Other Research Expertise (15)
About
Most Relevant Publications (2+)
15 total publications
Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors
Bioorganic & Medicinal Chemistry Letters / May 01, 2013
Chandrasekharappa, A. P., Badiger, S. E., Dubey, P. K., Panigrahi, S. K., & Manukonda, S. R. V. V. V. (2013). Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters, 23(9), 2579–2584. https://doi.org/10.1016/j.bmcl.2013.02.109
Design and Synthesis of Novel 2- Substituted Benzothiazole Compounds as PTP1B Inhibitors
Letters in Drug Design & Discovery / Mar 31, 2014
Chandrasekharappa, A., Badiger, S., Dubey, P., Panigrahi, S., & Manukonda, S. (2014). Design and Synthesis of Novel 2- Substituted Benzothiazole Compounds as PTP1B Inhibitors. Letters in Drug Design & Discovery, 11(4), 444–453. https://doi.org/10.2174/15701808113106660076
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Giuseppe Maria de Peppo
Research Director
Education
Ph.D, Stem Cells and Tissue Engineering / May, 2011
Politecnico di Milano
Master of Science, Material Science / February, 2006
Università degli Studi di Roma "La Sapienza"
Bachelor of Science, Biotechnology / September, 2003
Most Relevant Research Expertise
Other Research Expertise (21)
About
Most Relevant Publications (2+)
33 total publications
Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro
International Journal of Nanomedicine / May 01, 2014
de Peppo, G. M., Agheli, H., Karlsson, C., Ekstrom, K., Brisby, H., Lenneras, M., Gustafsson, S., Sjövall, P., Johansson, A., Olsson, E., Lausmaa, J., Thomsen, P., & Petronis, S. (2014). Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro. International Journal of Nanomedicine, 2499. https://doi.org/10.2147/ijn.s58805
A Polymer Canvas with the Stiffness of the Bone Matrix to Study and Control Mesenchymal Stem Cell Response
Advanced Healthcare Materials / Jan 13, 2023
Zanut, A., Li, R., Deng, R., Liu, X., Rejhon, M., Chen, W., Weck, M., de Peppo, G. M., & Riedo, E. (2023). A Polymer Canvas with the Stiffness of the Bone Matrix to Study and Control Mesenchymal Stem Cell Response. Advanced Healthcare Materials, 12(10). Portico. https://doi.org/10.1002/adhm.202201503
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Ratshilumela Steve Dima
CSIR
Education
University of Venda
PHD PHYSICS, PHYSICS
University of Venda
MSC PHYSICS, PHYSICS / December, 2017
University of Venda
BSC HONOURS (PHYSICS), PHYSICS / December, 2015
Experience
Council for Scientific and Industrial Research, South Africa
Senior Researcher / February, 2021 — Present
Council for Scientific and Industrial Research
PHD Fellow / February, 2019 — Present
University of Venda
Part-Time Physics Lecture / March, 2018 — January, 2019
DST-NRF Research Intern / April, 2017 — February, 2018
Most Relevant Research Expertise
Other Research Expertise (19)
About
Most Relevant Publications (1+)
13 total publications
Phase Separation of Br-Doped CsPbI3: A Combined Cluster Expansion, Monte Carlo, and DFT Study
Molecules / Dec 22, 2023
Maleka, P., Dima, R., Tshwane, D., Ntwaeaborwa, O., & Maphanga, R. (2023). Phase Separation of Br-Doped CsPbI3: A Combined Cluster Expansion, Monte Carlo, and DFT Study. Molecules, 29(1), 92. https://doi.org/10.3390/molecules29010092
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Kamal Al-Malah, Ph.D.
Aspen Plus and MATLAB Expert as Related to Modeling, Simulation, Design, and Economics of Chemical Processes
Education
Oregon State University
Ph.D., Chemical Engineering / September, 1993
Oregon State University
M.S., Chemical Engineering / March, 1991
Yarmouk University
B.S., Chemical Engineering / January, 1987
Experience
Higher Colleges of Technology
Faculty Member / August, 2015 — December, 2021
King Faisal University
Faculty Member / September, 2014 — June, 2015
University of Hail
Dept. Head/Faculty Member / September, 2009 — June, 2014
Most Relevant Research Expertise
Other Research Expertise (35)
About
Most Relevant Publications (1+)
41 total publications
OPTIMIZATION OF DRUG SOLUBILITY USING ASPEN PLUS: ACETYLSALICYLIC ACID (ASPIRIN) SOLUBILITY – A SECOND CASE STUDY
Asian Journal of Pharmaceutical and Clinical Research / Mar 17, 2020
AL-MALAH, K. I. (2020). OPTIMIZATION OF DRUG SOLUBILITY USING ASPEN PLUS: ACETYLSALICYLIC ACID (ASPIRIN) SOLUBILITY – A SECOND CASE STUDY. Asian Journal of Pharmaceutical and Clinical Research, 178–184. https://doi.org/10.22159/ajpcr.2020.v13i4.37143
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Morgan Edwards
Assistant Professor at University of Wisconsin--Madison and Director of the Climate Action Lab
Education
Massachusetts Institute of Technology
Data, Systems, and Society / June, 2017
Massachusetts Institute of Technology
S.M., Technology and Policy / June, 2013
University of North Carolina at Chapel Hill
B.S., Environmental Science and Economics / December, 2010
Experience
University of Wisconsin--Madison
Assistant Professor / August, 2020 — Present
University of Maryland
President's Postdoctoral Fellow / July, 2018 — June, 2020
Most Relevant Research Expertise
Other Research Expertise (16)
About
Most Relevant Publications (1+)
17 total publications
Satellite Data Applications for Sustainable Energy Transitions
Frontiers in Sustainability / Oct 03, 2022
Edwards, M. R., Holloway, T., Pierce, R. B., Blank, L., Broddle, M., Choi, E., Duncan, B. N., Esparza, Á., Falchetta, G., Fritz, M., Gibbs, H. K., Hundt, H., Lark, T., Leibrand, A., Liu, F., Madsen, B., Maslak, T., Pandey, B., Seto, K. C., & Stackhouse, P. W. (2022). Satellite Data Applications for Sustainable Energy Transitions. Frontiers in Sustainability, 3. https://doi.org/10.3389/frsus.2022.910924
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Jessica D. Hess, Ph.D.
T32 Postdoctoral Fellow at City of Hope Beckman Research Institute
Education
The University of Texas at El Paso
Graduate Certificate (Technical and Professional Writing) / March, 2023
The University of Texas at El Paso Department of Biological Sciences
Ph.D., Biological Sciences / December, 2022
Virginia Commonwealth University
B.S., Chemistry / May, 2015
Experience
City of Hope Beckman Research Institute
T32 Postdoctoral Fellow / January, 2023 — Present
The University of Texas at El Paso
Graduate Research & Teaching Assistant / August, 2017 — December, 2022
Most Relevant Research Expertise
Other Research Expertise (12)
About
Most Relevant Publications (1+)
11 total publications
Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells
European Journal of Pharmaceutical Sciences / Nov 01, 2020
Tilekar, K., Upadhyay, N., Schweipert, M., Hess, J. D., Macias, L. H., Mrowka, P., Meyer-Almes, F.-J., Aguilera, R. J., Iancu, C. V., Choe, J., & Ramaa, C. S. (2020). Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells. European Journal of Pharmaceutical Sciences, 154, 105512. https://doi.org/10.1016/j.ejps.2020.105512
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Thaddeus Allen
Professional who facilitates science, strategy and team building in biotech with a knack for deconstructing complexity to provide insight and direction.
Education
University of Toronto
PhD, Department of Medical Biophysics - Molecular and Cellular Biology of Cancer / April, 2004
University of Toronto
MSc, Department of Medical Biophysics - Molecular and Cellular Biology of Cancer / October, 1998
BSc, Biology/Pharmacology Co-op Program / May, 1995
Experience
The One Health Company
Scientific Writing Consultant / February, 2024 — Present
Science-based writing projects - The One Health Company offers next-generation sequencing screening of the canine cancer genome, coupled with matching targeted therapeutics.
Oncology Lead / August, 2018 — February, 2020
Product development, science consulting and writing projects related to PR, publications, legal and regulatory.
Tradewind BioScience, Inc.
CEO / January, 2018 — June, 2023
Startup that built an antibody for ovarian cancer treatment.
Anticancer Bioscience, Ltd.
VP Translational Biology and Business Development / August, 2018 — October, 2023
Hybrid position - responsible for both the mentoring of scientific teams researching small molecule drugs (MOA, PK, in vivo, etc.) and worked on strategic business development projects. Notably, the outward face of the company for partnering, vendor interactions and as a legal liaison.
Most Relevant Research Expertise
Other Research Expertise (24)
About
Most Relevant Publications (3+)
50 total publications
In-vitro metabolism of LXY18, an orally available, potent blocker of AURKB relocation in mitosis
Journal of Pharmaceutical and Biomedical Analysis / Aug 01, 2023
Li, J., Choudhry, N., Lv, G., Nimishetti, N., Reddy, M. C., Liu, H., Allen, T. D., Zhang, J., & Yang, D. (2023). In-vitro metabolism of LXY18, an orally available, potent blocker of AURKB relocation in mitosis. Journal of Pharmaceutical and Biomedical Analysis, 232, 115415. https://doi.org/10.1016/j.jpba.2023.115415
Integrating a phenotypic screening with a structural simplification strategy to identify 4-phenoxy-quinoline derivatives to potently disrupt the mitotic localization of Aurora kinase B
Bioorganic & Medicinal Chemistry / Feb 01, 2023
Lv, G., Shi, Q., Zhang, T., Li, J., Long, Y., Zhang, W., Choudhry, N., Yang, K., Li, H., Kalashova, J., Yang, C., Zhou, X., Reddy, M. C., Anantoju, K. K., Zhang, S., Zhang, J., Allen, T. D., Liu, H., Nimishetti, N., & Yang, D. (2023). Integrating a phenotypic screening with a structural simplification strategy to identify 4-phenoxy-quinoline derivatives to potently disrupt the mitotic localization of Aurora kinase B. Bioorganic & Medicinal Chemistry, 80, 117173. https://doi.org/10.1016/j.bmc.2023.117173
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects
Journal of Natural Products / Aug 18, 2021
Li, J., Yan, Z., Li, H., Shi, Q., Ahire, V., Zhang, S., Nimishetti, N., Yang, D., Allen, T. D., & Zhang, J. (2021). The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. Journal of Natural Products, 84(8), 2312–2320. https://doi.org/10.1021/acs.jnatprod.1c00429
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Example Pharmaceutical Science projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on Pharmaceutical Science?
Development of Novel Drug Delivery System
An academic researcher in Pharmaceutical Science can collaborate with a company to develop a novel drug delivery system. This project can involve the design and optimization of drug carriers, such as nanoparticles or liposomes, to improve drug stability, targeting, and release. The researcher can contribute expertise in formulation development, characterization techniques, and in vitro/in vivo evaluation.
Evaluation of Drug Efficacy and Safety
A company can collaborate with a Pharmaceutical Science researcher to evaluate the efficacy and safety of their drug candidates. The researcher can design and conduct preclinical and clinical trials, analyze the data, and provide insights on drug efficacy, dosage optimization, and potential side effects. This collaboration can help the company make informed decisions regarding drug development and regulatory submissions.
Optimization of Manufacturing Processes
Pharmaceutical Science researchers can collaborate with companies to optimize their manufacturing processes. They can analyze the existing manufacturing methods, identify areas for improvement, and propose strategies to enhance efficiency, reduce costs, and ensure product quality. This collaboration can lead to streamlined production processes and improved manufacturing outcomes.
Development of Personalized Medicine
Academic researchers in Pharmaceutical Science can collaborate with companies to develop personalized medicine approaches. They can contribute expertise in pharmacogenomics, biomarker identification, and drug response prediction. This collaboration can lead to the development of tailored treatment strategies, improved patient outcomes, and enhanced therapeutic efficacy.
Drug Formulation Optimization
A company can benefit from collaborating with a Pharmaceutical Science researcher to optimize their drug formulations. The researcher can analyze the physicochemical properties of the drug, evaluate different formulation approaches, and optimize drug solubility, stability, and bioavailability. This collaboration can result in improved drug formulations with enhanced therapeutic performance.